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Index > Protein center > SCN9A(Gene name) > Rabbit
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  • SCN9A (Gene name),
  • Sodium channel protein type 9 subunit alpha (Protein name ),  SCN9A_RABIT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SCN9A;
    Protein name:
    Sodium channel protein type 9 subunit alpha;
    Alternative:
    Schwann cell sodium channel;Nas;Voltage-gated sodium channel subunit alpha Nav1.7;Sodium channel protein type IX subunit alpha;
    Organism:
    Rabbit (Oryctolagus cuniculus). 
    General Annotation
    Sub Unit:
    The sodium channel consists of a large polypeptide and 2-3 smaller ones. This sequence represents a large polypeptide. Interacts with NEDD4 and NEDD4L.
    Function:
    Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.
    Subcellular Location:
    Membrane Multi-pass membrane protein In neurite terminals.
    Protein Attributes:
    Sequence length:
    1984
    Sequence:
    50:
    MAMLPPPGPQ | SFVRFTKQSL | ALIEQRIAEG | KTKEPKEEKK | DDHDEGPKPS | 
    100:
    SDLEAGKQLP | FIYGDIPAGM | VSEPLEDLDP | YYADKKTFIV | LNKGKAIFRF | 
    150:
    NATPALYILS | PFSPLRRISI | KILVHSLFSM | LIMCTILTNC | IFMTMNNPAE | 
    200:
    WTKNVEYTFT | GIYTFESLVK | IFARGFCVGE | FTFLRDPWNW | LDFIVIVFAY | 
    250:
    LTEFVNLGNV | SALRTFRVLR | ALKTISVIPG | LKTIVGALIQ | SVKKLSDVII | 
    300:
    LTVFCLSVFA | LIGLQLFMGH | LKHKCLRKIE | NETLESIMSS | IESEEDYKKY | 
    350:
    FYYLEGSKDA | LLCGFSTDSG | QCPEGYYCVK | AGRNPDYGYT | SFDTFSWAFL | 
    400:
    ALFRLMTQDY | WENLYQQTLR | AAGKTYMIFF | VVVIFLGSFY | LINLILAVVA | 
    450:
    MAYEEQNQAN | IEEAKQKELE | FQQMLDRLKK | EQEEAEAIAA | AAAEYTSIGR | 
    500:
    SRIMGLSESS | SETSKLSSKS | AKERRNRRKK | KNQKKLSSGE | EKGDDEKLSK | 
    550:
    SESEESISRK | QFHLGVEGHR | LAREKRLSAP | NQSPLSIRGS | LFSARRSSRT | 
    600:
    SLFSFKGRGK | DIGSETEFAD | DEHSIFGDNE | SRRGSLFVPQ | RPQERRSSNL | 
    650:
    SQASRSPPML | QMNGKMHSAV | DCNGVVSLVD | GPSALMLPNG | QLLPEVIIDK | 
    700:
    ATSDDSGTTQ | IRKKRRSSSY | LLSEDMLNDP | HLRQRAMSRA | SILTNTVEEL | 
    750:
    EESRQKCPSW | WYRFAHTFLI | WNCSPFWIKF | KKFIYIIVMD | PFVDLAITIC | 
    800:
    IVLNTLFMAM | EHHPMTEEFK | NVLVVGNLVF | TGIFAAEMVL | KLIAMDPYEY | 
    850:
    FQVGWNVFDS | LIVTLSLVEL | FLADVEGLSV | LRSFRLLRVF | KLAKSWPTLN | 
    900:
    MLIKIIGNSV | GPLGNLTLVL | AIIVFIFAVV | GMQLFGKSYK | ECVCKINDDC | 
    950:
    SLPRWHMNDF | FHSFLIVFRV | LCGEWIETMW | DCMEVAGQAM | CLIVYMMVMV | 
    1000:
    IGNLVVLNLF | LALLLSSFSS | DNLSAIEEDT | DANNLQIAVT | RIKKGINYVK | 
    1050:
    QTLRELILKA | FSKKPKISKE | IRQAEDLNSK | KENYISNRTL | AEMSKDYNFH | 
    1100:
    KEKDKISGFG | SSMDKYLMEE | SDHQSFIHNP | SLTVTVPIAP | GESDLENMNT | 
    1150:
    EELSSDSESE | YSKERLNRSS | SSECSTVDNA | LPGEGEEAEA | EPVNSDEPEA | 
    1200:
    CFTDGCVRRF | PCCQVSIESG | KGKIWWNIRK | TCYRIVEHSW | FESFIVLMIL | 
    1250:
    LSSGALAFED | IYIEKKKTIK | IILEYADKIF | TYIFILEMLL | KWVAYGYKTY | 
    1300:
    FTNAWCWLDF | LIVDVSLVTL | VANTLGYSDL | GPIKSLRTLR | ALRPLRALSR | 
    1350:
    FEGMRVVVNA | LIGAIPSIMN | VLLVCLIFWL | IFSIMGVNLF | AGKFYQCVNT | 
    1400:
    TDDSRFPTKQ | VSNRSECFAL | MNGSQNVRWK | NLKVNFDNVG | LRYLSLLQVA | 
    1450:
    TFKGWMDIMY | AAVDSVNVDQ | QPSYEHNLYM | YIYFVIFIIF | GSFFTLNLFI | 
    1500:
    GVIIDNFNQQ | KKKLGGQDIF | MTEEQKKYYN | AMKKLGSKKP | QKPIPRPGNK | 
    1550:
    FQGCIFDLVT | NQAFDITIMI | LICLNMVTMM | VEKEGQSDYM | TDVLYWINVV | 
    1600:
    FIILFTGECV | LKLISLRHYY | FTIGWNIFDF | VVVILSIVGM | FLAELIETYF | 
    1650:
    VSPTLFRVIR | LARIGRILRL | IKGAKGIRTL | LFALMMSLPA | LFNIGLLLFL | 
    1700:
    VMFIYAIFGM | SNFAYVKKEA | GINDMFNFET | FGNSMICLFQ | ITTSAGWDGL | 
    1750:
    LAPILNSAPP | DCDPKKVHPG | SSTEGDCGSP | SVGIFYFVSY | IIISFLVVVN | 
    1800:
    MYIAVILENF | SVATEESTEP | LSEDDFEMFY | EVWEKFDPDA | TQFIEYSKLS | 
    1850:
    DFAAALDPPL | LIAKPNKVQL | IAMDLPMVSG | DRIHCLDILF | AFTKRVLGES | 
    1900:
    GEMDSLRSQM | EERFMSANPS | KVSYEPITTT | LKRKQEDVSA | TVIQRAYRRY | 
    1950:
    RLRQNVKNIS | SIYIKEGDKD | DDLPNKGDIV | FDNVNSSSPE | KTDATASTIS | 
    1984:
    PPSYDSVTKP | DKEKYEKDKT | EKEDKGKDGK | ETKK
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rabbit Sodium channel protein type 9 subunit alpha
    Cat.:
    E15345h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rabbit Sodium channel protein type 9 subunit alpha
    MSDS:
    Please sign in first.
    ELISA Kit for Rabbit Sodium channel protein type 9 subunit alpha
    Cat.:
    E15345m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rabbit Sodium channel protein type 9 subunit alpha
    Cat.:
    E15345r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rabbit Sodium channel protein type 9 subunit alpha
    Cat.:
    U15345r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rabbit Sodium channel protein type 9 subunit alpha
    Cat.:
    U15345m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rabbit Sodium channel protein type 9 subunit alpha
    MSDS:
    Please sign in first.
    CLIA Kit for Rabbit Sodium channel protein type 9 subunit alpha
    Cat.:
    U15345h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rabbit Sodium channel protein type 9 subunit alpha
    Cat.:
    P15345Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rabbit Sodium channel protein type 9 subunit alpha
    Cat.:
    P15345Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rabbit Sodium channel protein type 9 subunit alpha
    Polyclonal Antibody for Rabbit Sodium channel protein type 9 subunit alpha
    Cat.:
    P15345Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rabbit Sodium channel protein type 9 subunit alpha
    Monoclonal Antibody for Rabbit Sodium channel protein type 9 subunit alpha
    Monoclonal Antibody for Rabbit Sodium channel protein type 9 subunit alpha
    Monoclonal Antibody for Rabbit Sodium channel protein type 9 subunit alpha
    Protein for Rabbit Sodium channel protein type 9 subunit alpha
    Protein for Rabbit Sodium channel protein type 9 subunit alpha
    Protein for Rabbit Sodium channel protein type 9 subunit alpha
    Protein for Rabbit Sodium channel protein type 9 subunit alpha

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    References
    1. 1.
      "Cloning of a sodium channel alpha subunit from rabbit Schwann cells."
      Belcher S.M. , Zerillo C.A. , Levenson R. , Ritchie J.M. , Howe J.R.
      Proc. Natl. Acad. Sci. U.S.A.92:11034-11038(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
      strain: New Zealand white.
      tissue: Schwann cell.
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