SGK3 ELISA Kit for Human(Homo sapiens) | EIAab.comSGK3 ELISA Kit for Human(Homo sapiens)

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SGK3 (Gene name),

Serine/threonine-protein kinase Sgk3 (Protein name ), SGK3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SGK3(SGK2;SGKL);

Protein name:

Serine/threonine-protein kinase Sgk3;

Alternative:

Serum/glucocorticoid-regulated kinase-like;Serum/glucocorticoid-regulated kinase 3;Serum/glucocorticoid-regulated kinase-like;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Involved in the activation of potassium channels. Mediates cell IL-3-dependent survival signals.

Subcellular Location:

Cytoplasmic vesicle Early endosome Localized in vesicle-like structures and in the early endosome.

Protein Attributes:

Sequence length:

496

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

496:

TAFTEETVPY | SVCVSSDYSI | VNASVLEADD | AFVGFSYAPP | SEDLFL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.613417

SMR:

Q96BR1

String:

Q96BR1

KEGG:

hsa:100533105

MIM:

607591

Pfam:

PF00069

STRING:

9606.ENSP00000262211

Uniprot:

Q96BR1

FOR

ELISA Kit for Human Serine/threonine-protein kinase Sgk3

CLIA Kit for Human Serine/threonine-protein kinase Sgk3

Polyclonal Antibody for Human Serine/threonine-protein kinase Sgk3

Monoclonal Antibody for Human Serine/threonine-protein kinase Sgk3

Protein for Human Serine/threonine-protein kinase Sgk3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase."
Kobayashi T. , Deak M. , Morrice N. , Cohen P.
Biochem. J.344:189-197(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PHOSPHORYLATION AT THR-320;MUTAGENESIS OF SER-486
2.

"Cloning and mapping of a novel human Serum/Glucocorticoid regulated kinase-like gene, SGKL, to chromosome 8q12.3-q13.1."
Dai F. , Yu L. , He H. , Zhao Y. , Yang J. , Zhang X. , Zhao S.
Genomics62:95-97(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

Zhao Y.
Submitted (2001-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Brain.
tissue: Mammary gland.
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Mammary gland.
7.

"Human serum and glucocorticoid-inducible kinase-like kinase (SGKL) phosphorylates glycogen syntheses kinase 3 beta (GSK-3beta) at serine-9 through direct interaction."
Dai F. , Yu L. , He H. , Chen Y. , Yu J. , Yang Y. , Xu Y. , Ling W. , Zhao S.
Biochem. Biophys. Res. Commun.293:1191-1196(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PHOSPHORYLATION OF GSK3B;INTERACTION WITH GSK3B
8.

"Activation of Na+/K+-ATPase by the serum and glucocorticoid-dependent kinase isoforms."
Henke G. , Setiawan I. , Boehmer C. , Lang F.
Kidney Blood Press. Res.25:370-374(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF NA(+)/K(+) ATPASE
9.

"K(+) channel activation by all three isoforms of serum- and glucocorticoid-dependent protein kinase SGK."
Gamper N. , Fillon S. , Feng Y. , Friedrich B. , Lang P.A. , Henke G. , Huber S.M. , Kobayashi T. , Cohen P. , Lang F.
Pflugers Arch.445:60-66(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
10.

"Serum and glucocorticoid inducible kinases in the regulation of the cardiac sodium channel SCN5A."
Boehmer C. , Wilhelm V. , Palmada M. , Wallisch S. , Henke G. , Brinkmeier H. , Cohen P. , Pieske B. , Lang F.
Cardiovasc. Res.57:1079-1084(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF SCN5A
11.

"Regulation of the glutamate transporter EAAT1 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid-inducible kinase isoforms SGK1/3 and protein kinase B."
Boehmer C. , Henke G. , Schniepp R. , Palmada M. , Rothstein J.D. , Broeer S. , Lang F.
J. Neurochem.86:1181-1188(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF SLC1A3/EAAT1
12.

"Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms."
Embark H.M. , Boehmer C. , Vallon V. , Luft F. , Lang F.
Pflugers Arch.445:601-606(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF KCNE1 AND KCNQ1
13.

"The serine/threonine kinases SGK2 and SGK3 are potent stimulators of the epithelial Na+ channel alpha,beta,gamma-ENaC."
Friedrich B. , Feng Y. , Cohen P. , Risler T. , Vandewalle A. , Broeer S. , Wang J. , Pearce D. , Lang F.
Pflugers Arch.445:693-696(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF SCNN1A/ENAC
14.

"Regulation of intestinal phosphate cotransporter NaPi IIb by ubiquitin ligase Nedd4-2 and by serum- and glucocorticoid-dependent kinase 1."
Palmada M. , Dieter M. , Speil A. , Boehmer C. , Mack A.F. , Wagner H.J. , Klingel K. , Kandolf R. , Murer H. , Biber J. , Closs E.I. , Lang F.
Am. J. Physiol.287:G143-G150(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF SLC34A2/NAPI-2B;FUNCTION IN PHOSPHORYLATION OF NEDD4L
15.

"Stimulation of renal Na+ dicarboxylate cotransporter 1 by Na+/H+ exchanger regulating factor 2, serum and glucocorticoid inducible kinase isoforms, and protein kinase B."
Boehmer C. , Embark H.M. , Bauer A. , Palmada M. , Yun C.H. , Weinman E.J. , Endou H. , Cohen P. , Lahme S. , Bichler K.H. , Lang F.
Biochem. Biophys. Res. Commun.313:998-1003(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF SLC13A2/NADC1
16.

"Regulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase isoforms SGK1 and SGK3 expressed in Xenopus oocytes."
Embark H.M. , Setiawan I. , Poppendieck S. , van de Graaf S.F. , Boehmer C. , Palmada M. , Wieder T. , Gerstberger R. , Cohen P. , Yun C.C. , Bindels R.J. , Lang F.
Cell. Physiol. Biochem.14:203-212(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF TRPV5
17.

"Peroxisomal targeting as a tool for assaying protein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner."
Nilsen T. , Slagsvold T. , Skjerpen C.S. , Brech A. , Stenmark H. , Olsnes S.
J. Biol. Chem.279:4794-4801(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PDPK1;PHOSPHORYLATION BY PDPK1
18.

"Regulation of the voltage gated K+ channel Kv1.3 by the ubiquitin ligase Nedd4-2 and the serum and glucocorticoid inducible kinase SGK1."
Henke G. , Maier G. , Wallisch S. , Boehmer C. , Lang F.
J. Cell. Physiol.199:194-199(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF KCNA3/KV1.3
19.

"Regulation of CLC-Ka/barttin by the ubiquitin ligase Nedd4-2 and the serum- and glucocorticoid-dependent kinases."
Embark H.M. , Boehmer C. , Palmada M. , Rajamanickam J. , Wyatt A.W. , Wallisch S. , Capasso G. , Waldegger P. , Seyberth H.W. , Waldegger S. , Lang F.
Kidney Int.66:1918-1925(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF BSND
20.

"The serine/threonine kinases SGK1, 3 and PKB stimulate the amino acid transporter ASCT2."
Palmada M. , Speil A. , Jeyaraj S. , Boehmer C. , Lang F.
Biochem. Biophys. Res. Commun.331:272-277(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF SLC1A5/ASCT2
21.

"Regulation of the excitatory amino acid transporter EAAT5 by the serum and glucocorticoid dependent kinases SGK1 and SGK3."
Boehmer C. , Rajamanickam J. , Schniepp R. , Kohler K. , Wulff P. , Kuhl D. , Palmada M. , Lang F.
Biochem. Biophys. Res. Commun.329:738-742(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF SLC1A7/EAAT5
22.

"Stimulation of the creatine transporter SLC6A8 by the protein kinases SGK1 and SGK3."
Shojaiefard M. , Christie D.L. , Lang F.
Biochem. Biophys. Res. Commun.334:742-746(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF SLC6A8
23.

"Upregulation of HERG channels by the serum and glucocorticoid inducible kinase isoform SGK3."
Maier G. , Palmada M. , Rajamanickam J. , Shumilina E. , Boehmer C. , Lang F.
Cell. Physiol. Biochem.18:177-186(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF KCNH2/HERG
24.

"CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4."
Slagsvold T. , Marchese A. , Brech A. , Stenmark H.
EMBO J.25:3738-3749(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH ITHC/AIP4;PHOSPHORYLATION AT SER-486
25.

"Role of the Phox homology domain and phosphorylation in activation of serum and glucocorticoid-regulated kinase-3."
Tessier M. , Woodgett J.R.
J. Biol. Chem.281:23978-23989(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-320 AND SER-486;MUTAGENESIS OF ARG-90 AND LYS-191
26.

"Regulation of the epithelial calcium channel TRPV6 by the serum and glucocorticoid-inducible kinase isoforms SGK1 and SGK3."
Boehmer C. , Palmada M. , Kenngott C. , Lindner R. , Klaus F. , Laufer J. , Lang F.
FEBS Lett.581:5586-5590(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF TRPV6
27.

"Identification of Flightless-I as a substrate of the cytokine-independent survival kinase CISK."
Xu J. , Liao L. , Qin J. , Xu J. , Liu D. , Songyang Z.
J. Biol. Chem.284:14377-14385(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PHOSPHORYLATION OF FLII;INTERACTION WITH FLII
28.

"The serum and glucocorticoid inducible kinases SGK1-3 stimulate the neutral amino acid transporter SLC6A19."
Boehmer C. , Sopjani M. , Klaus F. , Lindner R. , Laufer J. , Jeyaraj S. , Lang F. , Palmada M.
Cell. Physiol. Biochem.25:723-732(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF SLC6A19
29.

"Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids."
He P. , Lee S.J. , Lin S. , Seidler U. , Lang F. , Fejes-Toth G. , Naray-Fejes-Toth A. , Yun C.C.
Mol. Biol. Cell22:3812-3825(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF SLC9A3/NHE3;SUBCELLULAR LOCATION
30.

"SGK3 is an estrogen-inducible kinase promoting estrogen-mediated survival of breast cancer cells."
Wang Y. , Zhou D. , Phung S. , Masri S. , Smith D. , Chen S.
Mol. Endocrinol.25:72-82(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;TISSUE SPECIFICITY
31.

"Sgk kinases and their role in epithelial transport."
Loffing J. , Flores S.Y. , Staub O.
Annu. Rev. Physiol.68:461-490(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
32.

"Second AKT: the rise of SGK in cancer signalling."
Bruhn M.A. , Pearson R.B. , Hannan R.D. , Sheppard K.E.
Growth Factors28:394-408(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
33.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] VAL-92
34.

"Patterns of somatic mutation in human cancer genomes."
Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] PRO-355

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