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Index > Protein center > Shbg(Gene name) > Rat
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  • Shbg (Gene name),
  • Sex hormone-binding globulin (Protein name ),  SHBG_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Shbg;
    Protein name:
    Sex hormone-binding globulin(SHBG);
    Alternative:
    Testis-specific androgen-binding protein(ABP);Sex steroid-binding protein(SBP);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
    Subcellular Location:
    Secreted In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
    Protein Attributes:
    Sequence length:
    403
    Sequence:
    50:
    MEKGEVASLR | CRLLLLLLLL | TLPPTHQGRT | LRHIDPIQSA | QDSPAKYLSN | 
    100:
    GPGQEPVTVL | TIDLTKISKP | SSSFEFRTWD | PEGVIFYGDT | NTEDDWFMLG | 
    150:
    LRDGQLEIQL | HNLWARLTVG | FGPRLNDGRW | HPVELKMNGD | SLLLWVDGKE | 
    200:
    MLCLRQVSAS | LADHPQLSMR | IALGGLLLPT | SKLRFPLVPA | LDGCIRRDIW | 
    250:
    LGHQAQLSTS | ARTSLGNCDV | DLQPGLFFPP | GTHAEFSLQD | IPQPHTDPWT | 
    300:
    FSLELGFKLV | DGAGRLLTLG | TGTNSSWLTL | HLQDQTVVLS | SEAEPKLALP | 
    350:
    LAVGLPLQLK | LDVFKVALSQ | GPKMEVLSTS | LLRLASLWRL | WSHPQGHLSL | 
    400:
    GALPGEDSSA | SFCLSDLWVQ | GQRLDIDKAL | SRSQDIWTHS | CPQSPSNDTH | 
    403:
    TSH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat SHBG
    Cat.:
    E0396h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat SHBG
    Cat.:
    E0396r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat SHBG
    Cat.:
    E0396m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat SHBG
    MSDS:
    Please sign in first.
    CLIA Kit for Rat SHBG
    MSDS:
    Please sign in first.
    CLIA Kit for Rat SHBG
    Cat.:
    U0396r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat SHBG
    Cat.:
    U0396h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat SHBG
    Cat.:
    U0396m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat SHBG
    Cat.:
    P0396Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat SHBG
    Cat.:
    P0396Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat SHBG
    Polyclonal Antibody for Rat SHBG
    Cat.:
    P0396Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat SHBG
    Monoclonal Antibody for Rat SHBG
    Monoclonal Antibody for Rat SHBG
    Monoclonal Antibody for Rat SHBG
    Protein for Rat SHBG
    Protein for Rat SHBG
    Protein for Rat SHBG
    Protein for Rat SHBG
    Cat.:
    R0396h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%

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    References
    1. 1.
      "Rat androgen-binding protein: evidence for identical subunits and amino acid sequence homology with human sex hormone-binding globulin."
      Joseph D.R. , Hall S.H. , French F.S.
      Proc. Natl. Acad. Sci. U.S.A.84:339-343(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Testis.
    2. 2.
      "The gene structure of rat androgen-binding protein: identification of potential regulatory deoxyribonucleic acid elements of a follicle-stimulating hormone-regulated protein."
      Joseph D.R. , Hall S.H. , Conti M. , French F.S.
      Mol. Endocrinol.2:3-13(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Testis.
    4. 4.
      "Alternative processing of androgen-binding protein RNA transcripts in fetal rat liver. Identification of a transcript formed by trans splicing."
      Sullivan P.M. , Petrusz P. , Szpirer C. , Joseph D.R.
      J. Biol. Chem.266:143-154(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-239;ALTERNATIVE SPLICING
      strain: Sprague-Dawley.
      tissue: Fetal liver.
    5. 5.
      "Hormonal regulation of rat androgen-binding protein (ABP) messenger ribonucleic acid and homology of human testosterone-estradiol-binding globulin and ABP complementary deoxyribonucleic acids."
      Reventos J. , Hammond G.L. , Crozat A. , Brooks D.E. , Gunsalus G.L. , Bardin C.W. , Musto N.A.
      Mol. Endocrinol.2:125-132(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-403 (ISOFORM 1)
      tissue: Testis.
    6. 6.
      "Analysis of the steroid binding domain of rat androgen-binding protein."
      Danzo B.J. , Parrott J.A. , Skinner M.K.
      Endocrinology129:690-696(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 171-181
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