Sik2 ELISA Kit for Mouse(Mus musculus) | EIAab.comSik2 ELISA Kit for Mouse(Mus musculus)

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Sik2 (Gene name),

Serine/threonine-protein kinase SIK2 (Protein name ), SIK2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Sik2(Snf1lk2);

Protein name:

Serine/threonine-protein kinase SIK2;

Alternative:

Serine/threonine-protein kinase SNF1-like kinase 2;Salt-inducible protein kinase 2(SIK-2);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with and phosphorylates TORC2/CRTC2.

Function:

Phosphorylates 'Ser-789' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

931

Sequence:

50:

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931:

LSELPGLFDC | EMVEAVDPQH | NGVVSCLARE | T

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q8CFH6

UniGene:

Mm.104932

KEGG:

mmu:235344

String:

Q8CFH6

Pfam:

PF00069

Uniprot:

Q8CFH6

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ELISA Kit for Mouse Serine/threonine-protein kinase SIK2

Cat.:

E3357h

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Manual:

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96T

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ELISA Kit for Mouse Serine/threonine-protein kinase SIK2

MSDS:

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ELISA Kit for Mouse Serine/threonine-protein kinase SIK2

Cat.:

E3357m

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96T

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CLIA Kit for Mouse Serine/threonine-protein kinase SIK2

MSDS:

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CLIA Kit for Mouse Serine/threonine-protein kinase SIK2

Cat.:

U3357h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Serine/threonine-protein kinase SIK2

Cat.:

U3357m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Serine/threonine-protein kinase SIK2

Cat.:

P3357Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Serine/threonine-protein kinase SIK2

Cat.:

P3357Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Serine/threonine-protein kinase SIK2

Monoclonal Antibody for Mouse Serine/threonine-protein kinase SIK2

Protein for Mouse Serine/threonine-protein kinase SIK2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Adipose-specific expression, phosphorylation of Ser794 in insulin receptor substrate-1, and activation in diabetic animals of salt-inducible kinase-2."
Horike N. , Takemori H. , Katoh Y. , Doi J. , Min L. , Asano T. , Sun X.J. , Yamamoto H. , Kasayama S. , Muraoka M. , Nonaka Y. , Okamoto M.
J. Biol. Chem.278:18440-18447(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MUTAGENESIS OF LYS-49
tissue: Adipose tissue.
2.

"Silencing the constitutive active transcription factor CREB by the LKB1-SIK signaling cascade."
Katoh Y. , Takemori H. , Lin X.-Z. , Tamura M. , Muraoka M. , Satoh T. , Tsuchiya Y. , Min L. , Doi J. , Miyauchi A. , Witters L.A. , Nakamura H. , Okamoto M.
FEBS J.273:2730-2748(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ENZYME REGULATION;PHOSPHORYLATION AT THR-175 AND SER-587;MUTAGENESIS OF LYS-49 AND THR-175

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