Sirt1 ELISA Kit for Mouse(Mus musculus) | EIAab.comSirt1 ELISA Kit for Mouse(Mus musculus)

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Sirt1 (Gene name),

NAD-dependent protein deacetylase sirtuin-1 (Protein name ), SIR1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Sirt1(Sir2l1);

Protein name:

NAD-dependent protein deacetylase sirtuin-1;

Alternative:

SIR2-like protein 1;Regulatory protein SIR2 homolog 1;SIR2alpha(Sir2);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Found in a complex with PCAF and MYOD1 Component of the eNoSC complex, composed of SIRT1, SUV39H1 and RRP8. Interacts with HES1, HEY2 and PML. Interacts with RPS19BP1/AROS. Interacts with CCAR2 (via N-terminus); the interaction disrupts the interaction between SIRT1 and p53/TP53. Interacts with SETD7; the interaction induces the dissociation of SIRT1 from p53/TP53 and increases p53/TP53 activity. Interacts with MYCN, NR1I2, CREBZF, TSC2, TLE1, FOS, JUN, NR0B2, PPARG, NCOR, IRS1, IRS2 and NMNAT1. Interacts with HNF1A; the interaction occurs under nutrient restriction. Interacts with SUZ12; the interaction mediates the association with the PRC4 histone methylation complex which is specific as an association with PCR2 and PCR3 complex variants is not found. Interacts with FOXO1; the interaction deacetylates FOXO1, enhances its DNA-binding ability and increases its transcriptional activity. Interacts with BCL6; leads to a epigenetic repression of specific target genes.

Function:

SirtT1 75 kDa fragment: catalytically inactive 75SirT1 may be involved in regulation of apoptosis. May be involved in protecting chondrocytes from apoptotic death by associating with cytochrome C and interfering with apoptosome assembly.

Subcellular Location:

SirtT1 75 kDa fragment Cytoplasm Mitochondrion

Protein Attributes:

Sequence length:

737

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

737:

CAGGSGFGAD | GGDQEVVNEA | IATRQELTDV | NYPSDKS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q923E4

Pfam:

PF02146

UniGene:

Mm.351459

KEGG:

mmu:93759

Uniprot:

Q923E4

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ELISA Kit for Mouse NAD-dependent protein deacetylase sirtuin-1

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E3949h

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ELISA Kit for Mouse NAD-dependent protein deacetylase sirtuin-1

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E3949h

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ELISA Kit for Mouse NAD-dependent protein deacetylase sirtuin-1

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E3949m

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ELISA Kit for Mouse NAD-dependent protein deacetylase sirtuin-1

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E3949m

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96T

CLIA Kit for Mouse NAD-dependent protein deacetylase sirtuin-1

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U3949h

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96T

CLIA Kit for Mouse NAD-dependent protein deacetylase sirtuin-1

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U3949h

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96T

CLIA Kit for Mouse NAD-dependent protein deacetylase sirtuin-1

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U3949m

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CLIA Kit for Mouse NAD-dependent protein deacetylase sirtuin-1

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U3949m

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Polyclonal Antibody for Mouse NAD-dependent protein deacetylase sirtuin-1

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P3949Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse NAD-dependent protein deacetylase sirtuin-1

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P3949Rb-m

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Polyclonal Antibody for Mouse NAD-dependent protein deacetylase sirtuin-1

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P3949Rb-m

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Polyclonal Antibody for Mouse NAD-dependent protein deacetylase sirtuin-1

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P3949Rb-h

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Monoclonal Antibody for Mouse NAD-dependent protein deacetylase sirtuin-1

Protein for Mouse NAD-dependent protein deacetylase sirtuin-1

R&D Technical Data

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Precision

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Recovery

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References

1.

"Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase."
Imai S. , Armstrong C.M. , Kaeberlein M. , Guarente L.
Nature403:795-800(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Swiss Webster / NIH.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 545-737
tissue: Mammary tumor.
3.

"Negative control of p53 by Sir2alpha promotes cell survival under stress."
Luo J. , Nikolaev A.Y. , Imai S. , Chen D. , Su F. , Shiloh A. , Guarente L. , Gu W.
Cell107:137-148(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TP53;ENZYME REGULATION;MUTAGENESIS OF HIS-355
4.

"Acetylation of TAF(I)68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription."
Muth V. , Nadaud S. , Grummt I. , Voit R.
EMBO J.20:1353-1362(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF TAF1B
5.

"The absence of SIR2alpha protein has no effect on global gene silencing in mouse embryonic stem cells."
McBurney M.W. , Yang X. , Jardine K. , Bieman M. , Th'ng J. , Lemieux M.
Mol. Cancer Res.1:402-409(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis."
McBurney M.W. , Yang X. , Jardine K. , Hixon M. , Boekelheide K. , Webb J.R. , Lansdorp P.M. , Lemieux M.
Mol. Cell. Biol.23:38-54(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;DISRUPTION PHENOTYPE
7.

"Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state."
Fulco M. , Schiltz R.L. , Iezzi S. , King M.T. , Zhao P. , Kashiwaya Y. , Hoffman E. , Veech R.L. , Sartorelli V.
Mol. Cell12:51-62(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH MYOD1 AND PCAF;MUTAGENESIS OF HIS-355
8.

"Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice."
Cheng H.-L. , Mostoslavsky R. , Saito S. , Manis J.P. , Gu Y. , Patel P. , Bronson R. , Appella E. , Alt F.W. , Chua K.F.
Proc. Natl. Acad. Sci. U.S.A.100:10794-10799(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
9.

"Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma."
Picard F. , Kurtev M. , Chung N. , Topark-Ngarm A. , Senawong T. , Machado De Oliveira R. , Leid M. , McBurney M.W. , Guarente L.
Nature429:771-776(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN ADIPODIGENESIS;FUNCTION IN FAT MOBILIZATION;INTERACTION WITH PPARG AND NCOR1
10.

"Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases."
Hallows W.C. , Lee S. , Denu J.M.
Proc. Natl. Acad. Sci. U.S.A.103:10230-10235(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF ACSS2;FUNCTION IN REGULATION OF ACCS2
11.

"SIRT1 deacetylates and positively regulates the nuclear receptor LXR."
Li X. , Zhang S. , Blander G. , Tse J.G. , Krieger M. , Guarente L.
Mol. Cell28:91-106(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF NR1H3 AND NR1H2;FUNCTION IN REGULATION OF NR1H3
12.

"SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization."
Han M.K. , Song E.K. , Guo Y. , Ou X. , Mantel C. , Broxmeyer H.E.
Cell Stem Cell2:241-251(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN APOPTOSIS
13.

"Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity."
Daitoku H. , Hatta M. , Matsuzaki H. , Aratani S. , Ohshima T. , Miyagishi M. , Nakajima T. , Fukamizu A.
Proc. Natl. Acad. Sci. U.S.A.101:10042-10047(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FOXO1;FUNCTION IN DEACETYLATION OF FOXO1;MUTAGENESIS OF HIS-355
14.

"Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses."
Chen W.Y. , Wang D.H. , Yen R.C. , Luo J. , Gu W. , Baylin S.B.
Cell123:437-448(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIC1
15.

"Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice."
Moynihan K.A. , Grimm A.A. , Plueger M.M. , Bernal-Mizrachi E. , Ford E. , Cras-Meneur C. , Permutt M.A. , Imai S.
Cell Metab.2:105-117(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF INSULIN SECRETION
16.

"SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1."
Bouras T. , Fu M. , Sauve A.A. , Wang F. , Quong A.A. , Perkins N.D. , Hay R.T. , Gu W. , Pestell R.G.
J. Biol. Chem.280:10264-10276(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
17.

"Nuclear trapping of the forkhead transcription factor FoxO1 via Sirt-dependent deacetylation promotes expression of glucogenetic genes."
Frescas D. , Valenti L. , Accili D.
J. Biol. Chem.280:20589-20595(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF FOXO1
18.

"Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1."
Rodgers J.T. , Lerin C. , Haas W. , Gygi S.P. , Spiegelman B.M. , Puigserver P.
Nature434:113-118(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF PPARGC1A;FUNCTION IN REGULATION OF GLUCOSE HOMEOSTASIS;INDUCTION
19.

"Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS."
Nisoli E. , Tonello C. , Cardile A. , Cozzi V. , Bracale R. , Tedesco L. , Falcone S. , Valerio A. , Cantoni O. , Clementi E. , Moncada S. , Carruba M.O.
Science310:314-317(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
20.

"Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage."
Wang C. , Chen L. , Hou X. , Li Z. , Kabra N. , Ma Y. , Nemoto S. , Finkel T. , Gu W. , Cress W.D. , Chen J.
Nat. Cell Biol.8:1025-1031(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH E2F1;MUTAGENESIS OF HIS-355
21.

"Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells."
Bordone L. , Motta M.C. , Picard F. , Robinson A. , Jhala U.S. , Apfeld J. , McDonagh T. , Lemieux M. , McBurney M. , Szilvasi A. , Easlon E.J. , Lin S.J. , Guarente L.
PLoS Biol.4:E31-E31(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF INSULIN SECRETION
22.

"Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1."
Wong S. , Weber J.D.
Biochem. J.407:451-460(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF RB1
23.

"Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha."
Gerhart-Hines Z. , Rodgers J.T. , Bare O. , Lerin C. , Kim S.H. , Mostoslavsky R. , Alt F.W. , Wu Z. , Puigserver P.
EMBO J.26:1913-1923(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF PPARGC1A;FUNCTION IN REGULATION OF MUSCLE METABOLISM
24.

"SIRT1 inhibits transforming growth factor beta-induced apoptosis in glomerular mesangial cells via Smad7 deacetylation."
Kume S. , Haneda M. , Kanasaki K. , Sugimoto T. , Araki S. , Isshiki K. , Isono M. , Uzu T. , Guarente L. , Kashiwagi A. , Koya D.
J. Biol. Chem.282:151-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF SMAD7
25.

"Nucleocytoplasmic shuttling of the NAD+-dependent histone deacetylase SIRT1."
Tanno M. , Sakamoto J. , Miura T. , Shimamoto K. , Horio Y.
J. Biol. Chem.282:6823-6832(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;MUTAGENESIS OF 38-ARG-ARG-39; 138-LEU--LEU-145; 227-LYS--LYS-230 AND 425-VAL--ILE-431
26.

"The direct involvement of SirT1 in insulin-induced insulin receptor substrate-2 tyrosine phosphorylation."
Zhang J.
J. Biol. Chem.282:34356-34364(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH IRS1 AND IRS2
27.

"SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation."
Vaquero A. , Scher M. , Erdjument-Bromage H. , Tempst P. , Serrano L. , Reinberg D.
Nature450:440-444(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;DISRUPTION PHENOTYPE
28.

"SIRT1 regulates circadian clock gene expression through PER2 deacetylation."
Asher G. , Gatfield D. , Stratmann M. , Reinke H. , Dibner C. , Kreppel F. , Mostoslavsky R. , Alt F.W. , Schibler U.
Cell134:317-328(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INDUCTION;INTERACTION WITH CLOCK; ARNTL AND PER2
29.

"The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control."
Nakahata Y. , Kaluzova M. , Grimaldi B. , Sahar S. , Hirayama J. , Chen D. , Guarente L.P. , Sassone-Corsi P.
Cell134:329-340(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION;INTERACTION WITH CLOCK AND ARNTL
30.

"Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt."
Fulco M. , Cen Y. , Zhao P. , Hoffman E.P. , McBurney M.W. , Sauve A.A. , Sartorelli V.
Dev. Cell14:661-673(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
31.

"sirt1-null mice develop an autoimmune-like condition."
Sequeira J. , Boily G. , Bazinet S. , Saliba S. , He X. , Jardine K. , Kennedy C. , Staines W. , Rousseaux C. , Mueller R. , McBurney M.W.
Exp. Cell Res.314:3069-3074(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
32.

"SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation."
Lan F. , Cacicedo J.M. , Ruderman N. , Ido Y.
J. Biol. Chem.283:27628-27635(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF STK11;FUNCTION IN POSSIBLE REGULATION OF STK11
33.

"Sirt1 deficiency attenuates spermatogenesis and germ cell function."
Coussens M. , Maresh J.G. , Yanagimachi R. , Maeda G. , Allsopp R.
PLoS ONE3:E1571-E1571(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
34.

"A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy."
Lee I.H. , Cao L. , Mostoslavsky R. , Lombard D.B. , Liu J. , Bruns N.E. , Tsokos M. , Alt F.W. , Finkel T.
Proc. Natl. Acad. Sci. U.S.A.105:3374-3379(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN AUTOPHAGY
35.

"Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation."
Purushotham A. , Schug T.T. , Xu Q. , Surapureddi S. , Guo X. , Li X.
Cell Metab.9:327-338(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN REGULATION OF PPARA;INTERACTION WITH PPARA
36.

"Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters."
Zhang T. , Berrocal J.G. , Frizzell K.M. , Gamble M.J. , DuMond M.E. , Krishnakumar R. , Yang T. , Sauve A.A. , Kraus W.L.
J. Biol. Chem.284:20408-20417(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NMNAT1
37.

"CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage."
Kang H. , Jung J.W. , Kim M.K. , Chung J.H.
PLoS ONE4:E6611-E6611(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-649;MUTAGENESIS OF SER-154; SER-649; SER-651 AND SER-683
38.

"Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis."
Ramsey K.M. , Yoshino J. , Brace C.S. , Abrassart D. , Kobayashi Y. , Marcheva B. , Hong H.K. , Chong J.L. , Buhr E.D. , Lee C. , Takahashi J.S. , Imai S. , Bass J.
Science324:651-654(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ARNTL
39.

"SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism."
Ponugoti B. , Kim D.H. , Xiao Z. , Smith Z. , Miao J. , Zang M. , Wu S.Y. , Chiang C.M. , Veenstra T.D. , Kemper J.K.
J. Biol. Chem.285:33959-33970(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DEACETYLATION OF SREBF1;FUNCTION IN REGULATION OF SREBF1
40.

"SIRT1 contributes to telomere maintenance and augments global homologous recombination."
Palacios J.A. , Herranz D. , De Bonis M.L. , Velasco S. , Serrano M. , Blasco M.A.
J. Cell Biol.191:1299-1313(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN TELOMERE MAINTENANCE
41.

"DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1."
Guo X. , Williams J.G. , Schug T.T. , Li X.
J. Biol. Chem.285:13223-13232(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-522;MUTAGENESIS OF THR-522
42.

"GAPDH mediates nitrosylation of nuclear proteins."
Kornberg M.D. , Sen N. , Hara M.R. , Juluri K.R. , Nguyen J.V. , Snowman A.M. , Law L. , Hester L.D. , Snyder S.H.
Nat. Cell Biol.12:1094-1100(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: S-NITROSYLATION AT CYS-387 AND CYS-390;MUTAGENESIS OF CYS-363; CYS-366; CYS-387 AND CYS-390
43.

"KRIT1 regulates the homeostasis of intracellular reactive oxygen species."
Goitre L. , Balzac F. , Degani S. , Degan P. , Marchi S. , Pinton P. , Retta S.F.
PLoS ONE5:E11786-E11786(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FOXO1
44.

"SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53."
Lynch C.J. , Shah Z.H. , Allison S.J. , Ahmed S.U. , Ford J. , Warnock L.J. , Li H. , Serrano M. , Milner J.
PLoS ONE5:E13502-E13502(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORM 2)
45.

"A nutrient-sensitive interaction between Sirt1 and HNF-1alpha regulates Crp expression."
Grimm A.A. , Brace C.S. , Wang T. , Stormo G.D. , Imai S.
Aging Cell10:305-317(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH HNF1A
46.

"Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation."
Powell M.J. , Casimiro M.C. , Cordon-Cardo C. , He X. , Yeow W.S. , Wang C. , McCue P.A. , McBurney M.W. , Pestell R.G.
Cancer Res.71:964-975(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN AUTOPHAGY;DISRUPTION PHENOTYPE
47.

"MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1."
Zhu H. , Yang Y. , Wang Y. , Li J. , Schiller P.W. , Peng T.
Cardiovasc. Res.92:75-84(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PALMITATE-INDUCED APOPTOSIS;INDUCTION;DOWN-REGULATION BY PALMITATE
48.

"Novel repressor regulates insulin sensitivity through interaction with Foxo1."
Nakae J. , Cao Y. , Hakuno F. , Takemori H. , Kawano Y. , Sekioka R. , Abe T. , Kiyonari H. , Tanaka T. , Sakai J. , Takahashi S. , Itoh H.
EMBO J.31:2275-2295(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FOXO1
49.

"BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets."
Tiberi L. , van den Ameele J. , Dimidschstein J. , Piccirilli J. , Gall D. , Herpoel A. , Bilheu A. , Bonnefont J. , Iacovino M. , Kyba M. , Bouschet T. , Vanderhaeghen P.
Nat. Neurosci.15:1627-1635(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN NEUROGENESIS;INTERACTION WITH BCL6

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