Smad9 ELISA Kit for Mouse(Mus musculus) | EIAab.comSmad9 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Smad9(Gene name) > Mouse

Smad9 (Gene name),

Mothers against decapentaplegic homolog 9 (Protein name ), SMAD9_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Smad9(Madh8;Madh9;Smad8);

Protein name:

Mothers against decapentaplegic homolog 9(MAD homolog 9;Mothers against DPP homolog 9);

Alternative:

Smad8;SMAD family member 9(SMAD 9;Smad9);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interaction with the co-SMAD SMAD4. Interacts with PEBP2-alpha subunit.

Function:

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.

Subcellular Location:

Cytoplasm Nucleus Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.

Protein Attributes:

Sequence length:

430

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

430:

IEIHLHGPLQ | WLDKVLTQMG | SPHNPISSVS |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9JIW5

KEGG:

mmu:55994

UniGene:

Mm.244353

Pfam:

PF03165

SMR:

Q9JIW5

Uniprot:

Q9JIW5

FOR

ELISA Kit for Mouse MAD homolog 9

CLIA Kit for Mouse MAD homolog 9

Polyclonal Antibody for Mouse MAD homolog 9

Monoclonal Antibody for Mouse MAD homolog 9

Protein for Mouse MAD homolog 9

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Mouse Smad8 phosphorylation downstream of BMP receptors ALK-2, ALK-3, and ALK-6 induces its association with Smad4 and transcriptional activity."
Kawai S. , Faucheu C. , Gallea S. , Spinella-Jaegle S. , Atfi A. , Baron R. , Roman-Roman S.
Biochem. Biophys. Res. Commun.271:682-687(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION;VARIANT 214-SER-GLU-215 DEL
tissue: Embryo.
2.

Kawai S. , Roman-Roman S.
Submitted (2002-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO 115 AND 135
3.

"Mouse Smad8 protein mRNA alternative form (6-bp insert in linker region)."
Kawai S. , Roman-Roman S.
Submitted (2002-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6J.
tissue: Embryo.

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