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Index > Protein center > SMUG1(Gene name) > Bovine
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  • SMUG1 (Gene name),
  • Single-strand selective monofunctional uracil DNA glycosylase (Protein name ),  SMUG1_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SMUG1;
    Protein name:
    Single-strand selective monofunctional uracil DNA glycosylase;
    Alternative:

    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Responsible for recognizing base lesions in the genome and initiating base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. The activity is greater against mismatches (U/G) than against matches (U/A). Excised uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine) and other oxidized damage. The activity is damage specificity and salt concentration-dependent. The general order of the preference for ssDNA and dsDNA is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at the low salt concentration. At the high concentration dsDNA (G pair) > dsDNA (A pair) > ssDNA.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    272
    Sequence:
    50:
    MAVPQPFPSG | PHLQPAGALM | EPQPSPRSLA | EGFLQEELRL | NDELRQLQFS | 
    100:
    ELVGIVYNPV | EYAWEPHRSY | VTRYCQGPKQ | VLFLGMNPGP | FGMAQTGVPF | 
    150:
    GEVSVVRDWL | GLGGPVRTPP | QEHPKRPVLG | LECPQSEVSG | ARFWGFFRNL | 
    200:
    CGQPEVFFRH | CFVHNLCPLL | LLAPSGRNIT | PAELPAKQRE | QLLGVCDAAL | 
    250:
    CRQVQLLGVR | LVVGVGRVAE | QRARRALASL | MPEVQVEGLL | HPSPRSPQAN | 
    272:
    KGWEAVAKER | LNELGLLPLL | TS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    ELISA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    ELISA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    ELISA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    CLIA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    CLIA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    CLIA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    CLIA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Polyclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Polyclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Polyclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Polyclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Monoclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Monoclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Monoclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Monoclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Protein for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Protein for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Protein for Bovine Single-strand selective monofunctional uracil DNA glycosylase
    Protein for Bovine Single-strand selective monofunctional uracil DNA glycosylase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Linkage analysis reveals two independent loci for ocular disorders in a local Japanese Black cattle population."
      Ihara N. , Fujita T. , Shiga K. , Itoh M. , Watanabe T. , Sugimoto Y.
      Anim. Genet.36:132-134(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Pancreas.
    2. 2.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Fetal brain.
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