Protein name:
Single-strand selective monofunctional uracil DNA glycosylase ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Function:
Responsible for recognizing base lesions in the genome and initiating base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. The activity is greater against mismatches (U/G) than against matches (U/A). Excised uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine) and other oxidized damage. The activity is damage specificity and salt concentration-dependent. The general order of the preference for ssDNA and dsDNA is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at the low salt concentration. At the high concentration dsDNA (G pair) > dsDNA (A pair) > ssDNA.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MAVPQPFPSG | PHLQPAGALM | EPQPSPRSLA | EGFLQEELRL | NDELRQLQFS |
100:
ELVGIVYNPV | EYAWEPHRSY | VTRYCQGPKQ | VLFLGMNPGP | FGMAQTGVPF |
150:
GEVSVVRDWL | GLGGPVRTPP | QEHPKRPVLG | LECPQSEVSG | ARFWGFFRNL |
200:
CGQPEVFFRH | CFVHNLCPLL | LLAPSGRNIT | PAELPAKQRE | QLLGVCDAAL |
250:
CRQVQLLGVR | LVVGVGRVAE | QRARRALASL | MPEVQVEGLL | HPSPRSPQAN |
272:
KGWEAVAKER | LNELGLLPLL | TS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Bovine
ELISA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
ELISA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
ELISA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
ELISA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
CLIA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
CLIA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
CLIA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
CLIA Kit for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Polyclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Polyclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Polyclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Polyclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Monoclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Monoclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Monoclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Monoclonal Antibody for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Protein for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Protein for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Protein for Bovine Single-strand selective monofunctional uracil DNA glycosylase
Protein for Bovine Single-strand selective monofunctional uracil DNA glycosylase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Pancreas .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Fetal brain .