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Index > Protein center > Smyd1(Gene name) > Mouse
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  • Smyd1 (Gene name),
  • SET and MYND domain-containing protein 1 (Protein name ),  SMYD1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Smyd1(Bop);
    Protein name:
    SET and MYND domain-containing protein 1;
    Alternative:
    Zinc finger protein BOP(m-BOP);CD8b-opposite;Zinc finger protein BOP(m-BOP);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with HDAC1, HDAC2 and HDAC3.
    Function:
    Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.
    Subcellular Location:
    Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    490
    Sequence:
    50:
    MTIGSMENVE | VFTSEGKGRG | LKATKEFWAA | DVIFAERAYS | AVVFDSLINF | 
    100:
    VCHTCFKRQE | KLHRCGQCKF | AHYCDRTCQK | DAWLNHKNEC | AAIKKYGKVP | 
    150:
    NENIRLAARI | MWRVEREGTG | LTEGCLVSVD | DLQNHVEHFG | EEEQKELRVD | 
    200:
    VDTFLQYWPP | QSQQFSMQYI | SHIFGVINCN | GFTLSDQRGL | QAVGVGIFPN | 
    250:
    LGLVNHDCWP | NCTVIFNNGN | HEAVKSMFHT | QMRIELRALG | KISEGEELTV | 
    300:
    SYIDFLHLSE | ERRRQLKKQY | YFDCSCEHCQ | KGLKDDLFLA | AKEDPKPSQE | 
    350:
    VVKEMIQFSK | DTLEKIDKAR | SEGLYHEVVK | LCRECLEKQE | PVFADTNLYV | 
    400:
    LRLLSIASEV | LSYLQAYEEA | SHYARRMVDG | YMKLYHHNNA | QLGMAVMRAG | 
    450:
    LTNWHAGHIE | VGHGMICKAY | AILLVTHGPS | HPITKDLEAM | RMQTEMELRM | 
    490:
    FRQNEFMYHK | MREAALNNQP | MQVMAEPSNE | PAPALFHKKQ | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    String:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse SET and MYND domain-containing protein 1
    ELISA Kit for Mouse SET and MYND domain-containing protein 1
    CLIA Kit for Mouse SET and MYND domain-containing protein 1
    CLIA Kit for Mouse SET and MYND domain-containing protein 1
    Polyclonal Antibody for Mouse SET and MYND domain-containing protein 1
    Polyclonal Antibody for Mouse SET and MYND domain-containing protein 1
    Monoclonal Antibody for Mouse SET and MYND domain-containing protein 1
    Monoclonal Antibody for Mouse SET and MYND domain-containing protein 1
    Protein for Mouse SET and MYND domain-containing protein 1
    Protein for Mouse SET and MYND domain-containing protein 1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The Bop gene adjacent to the mouse CD8b gene encodes distinct zinc-finger proteins expressed in CTLs and in muscle."
      Hwang I. , Gottlieb P.D.
      J. Immunol.158:1165-1174(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3);TISSUE SPECIFICITY;VARIANTS ARG-95; LEU-160 AND THR-344
      strain: BALB/c.
      strain: C57BL/6.
      tissue: Skeletal muscle.
      tissue: Spleen.
    2. 2.
      Gottlieb P.D. , Hwang I.
      Submitted (1999-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO N-TERMINUS
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Heart.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFOFRM 1)
      strain: C57BL/6.
      tissue: Eye.
    6. 6.
      "Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis."
      Gottlieb P.D. , Pierce S.A. , Sims R.J. III , Yamagishi H. , Weihe E.K. , Harriss J.V. , Maika S.D. , Kuziel W.A. , King H.L. , Olson E.N. , Nakagawa O. , Srivastava D.
      Nat. Genet.31:25-32(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH HDAC1; HDAC2 AND HDAC3
    7. 7.
      "Crystal structure of cardiac-specific histone methyltransferase SmyD1 reveals unusual active site architecture."
      Sirinupong N. , Brunzelle J. , Ye J. , Pirzada A. , Nico L. , Yang Z.
      J. Biol. Chem.285:40635-40644(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) IN COMPLEX WITH S-ADENOSYL-ORNITHINE;CATALYTIC ACTIVITY;ZINC-BINDING SITES;FUNCTION;INTERACTION WITH NACA ISOFORM SKNAC
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