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Index > Protein center > Snf8(Gene name) > Mouse
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  • Snf8 (Gene name),
  • Vacuolar-sorting protein SNF8 (Protein name ),  SNF8_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Snf8(D11Moh34);
    Protein name:
    Vacuolar-sorting protein SNF8;
    Alternative:
    ESCRT-II complex subunit VPS22;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the endosomal sorting complex required for transport II (ESCRT-II), composed of SNF8, VPS25 and VPS36. SNF8 is essential for the stability of the ESCRT-II complex. ESCRT-II interacts with ELL. Interacts with TSG101 (via the C-terminal domain). Interacts with RILPL1 (via the N-terminal domain); which recruits ESCRT-II to the endosome membranes. Interacts with 14-3-3 proteins.
    Function:
    Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization.
    Subcellular Location:
    Cytoplasm Endosome membrane Nucleus Late endosome membrane Recruited to the endosome membrane to participate in vesicle formation.
    Protein Attributes:
    Sequence length:
    258
    Sequence:
    50:
    MHRRGVGAGA | IAKKKLAEAK | YKERGTVLAE | DQLAQMSKQL | DMFKTNLEEF | 
    100:
    ASKHKQEIRK | NPEFRVQFQD | MCATIGVDPL | ASGKGFWSEM | LGVGDFYYEL | 
    150:
    GVQIIEVCLA | LKHRNGGLIT | LEELHQQVLK | GRGKFAQDVS | QDDLIRAIKK | 
    200:
    LKALGTGFGI | IPVGGTYLIQ | SVPAELNMDH | TVVLQLAEKN | GYVTVSEIKT | 
    250:
    SLKWETERAR | QVLEHLLKEG | LAWLDLQAPG | EAHYWLPALF | TDLYSQEISA | 
    258:
    EEAKEAFP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Vacuolar-sorting protein SNF8
    ELISA Kit for Mouse Vacuolar-sorting protein SNF8
    ELISA Kit for Mouse Vacuolar-sorting protein SNF8
    CLIA Kit for Mouse Vacuolar-sorting protein SNF8
    CLIA Kit for Mouse Vacuolar-sorting protein SNF8
    CLIA Kit for Mouse Vacuolar-sorting protein SNF8
    Polyclonal Antibody for Mouse Vacuolar-sorting protein SNF8
    Polyclonal Antibody for Mouse Vacuolar-sorting protein SNF8
    Polyclonal Antibody for Mouse Vacuolar-sorting protein SNF8
    Monoclonal Antibody for Mouse Vacuolar-sorting protein SNF8
    Monoclonal Antibody for Mouse Vacuolar-sorting protein SNF8
    Monoclonal Antibody for Mouse Vacuolar-sorting protein SNF8
    Protein for Mouse Vacuolar-sorting protein SNF8
    Protein for Mouse Vacuolar-sorting protein SNF8
    Protein for Mouse Vacuolar-sorting protein SNF8

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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary tumor.
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