SNIP1 ELISA Kit for Human(Homo sapiens) | EIAab.comSNIP1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > SNIP1(Gene name) > Human

SNIP1 (Gene name),

Smad nuclear-interacting protein 1 (Protein name ), SNIP1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SNIP1;

Protein name:

Smad nuclear-interacting protein 1;

Alternative:

FHA domain-containing protein SNIP1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds SMAD4 and CREBBP/EP300. Binds the SMAD1/OAZ1/PSMB4 complex. Interacts with DROSHA.

Function:

Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

396

Sequence:

50:

100:

150:

200:

250:

300:

350:

396:

ELKEKDVLKF | GFSSREYVLL | HESSDTSEID | RKDDEDEEEE | EEVSDS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000296215

String:

Q8TAD8

MIM:

608241

SMR:

Q8TAD8

Pfam:

PF00498

KEGG:

hsa:79753

UniGene:

Hs.471951

UniGene:

Hs.47232

Uniprot:

Q8TAD8

FOR

ELISA Kit for Human Smad nuclear-interacting protein 1

CLIA Kit for Human Smad nuclear-interacting protein 1

Polyclonal Antibody for Human Smad nuclear-interacting protein 1

Monoclonal Antibody for Human Smad nuclear-interacting protein 1

Protein for Human Smad nuclear-interacting protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A novel Smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction."
Kim R.H. , Wang D. , Tsang M. , Martin J. , Huff C. , de Caestecker M.P. , Parks T.W. , Meng X. , Lechleider R.J. , Wang T. , Roberts A.B.
Genes Dev.14:1605-1616(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH SMAD4 AND CREBBP/EP300;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue: Embryonic kidney.
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Teratocarcinoma.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.
4.

"SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators."
Kim R.H. , Flanders K.C. , Birkey Reffey S. , Anderson L.A. , Duckett C.S. , Perkins N.D. , Roberts A.B.
J. Biol. Chem.276:46297-46304(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CREBBP AND EP300
5.

"A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs)."
Lin Y. , Martin J. , Gruendler C. , Farley J. , Meng X. , Li B.-Y. , Lechleider R. , Huff C. , Kim R.H. , Grasser W.A. , Paralkar V. , Wang T.
BMC Cell Biol.3:15-15(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH THE SMAD1/OAZ1/PSMB4 COMPLEX;DEGRADATION BY THE PROTEASOME
6.

"The FHA domain protein SNIP1 is a regulator of the cell cycle and cyclin D1 expression."
Roche K.C. , Wiechens N. , Owen-Hughes T. , Perkins N.D.
Oncogene23:8185-8195(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SMARCA4
7.

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-35;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
8.

"PDSM, a motif for phosphorylation-dependent SUMO modification."
Hietakangas V. , Anckar J. , Blomster H.A. , Fujimoto M. , Palvimo J.J. , Nakai A. , Sistonen L.
Proc. Natl. Acad. Sci. U.S.A.103:45-50(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-30;MUTAGENESIS OF LYS-30
9.

"Regulation of cyclin D1 RNA stability by SNIP1."
Bracken C.P. , Wall S.J. , Barre B. , Panov K.I. , Ajuh P.M. , Perkins N.D.
Cancer Res.68:7621-7628(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE SNARP COMPLEX
10.

"The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis."
Yu B. , Bi L. , Zheng B. , Ji L. , Chevalier D. , Agarwal M. , Ramachandran V. , Li W. , Lagrange T. , Walker J.C. , Chen X.
Proc. Natl. Acad. Sci. U.S.A.105:10073-10078(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH DROSHA
11.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-49; SER-52 AND SER-54;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
12.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-52;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
13.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-35 AND SER-394;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
14.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-35 AND SER-54;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
15.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
16.

"Genetic mapping and exome sequencing identify variants associated with five novel diseases."
Puffenberger E.G. , Jinks R.N. , Sougnez C. , Cibulskis K. , Willert R.A. , Achilly N.P. , Cassidy R.P. , Fiorentini C.J. , Heiken K.F. , Lawrence J.J. , Mahoney M.H. , Miller C.J. , Nair D.T. , Politi K.A. , Worcester K.N. , Setton R.A. , Dipiazza R. , Sherman E.A. , more...
PLoS ONE7:E28936-E28936(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PMRED GLY-366

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