SNW1 ELISA Kit for Human(Homo sapiens) | EIAab.comSNW1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > SNW1(Gene name) > Human

SNW1 (Gene name),

SNW domain-containing protein 1 (Protein name ), SNW1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SNW1(SKIIP;SKIP);

Protein name:

SNW domain-containing protein 1;

Alternative:

Nuclear receptor coactivator NCoA-62;Nuclear protein SkiP;Ski-interacting protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with ATP1B4 (By similarity). Interacts with the SKI oncogene and with CHES1/FOXN3. Identified in the spliceosome C complex. Also associates with non-spliceosomal proteins.

Function:

Involved in vitamin D-mediated transcription. Can function as a splicing factor in pre-mRNA splicing.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

536

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

536:

LDKFLEEAKQ | HGGSKRPSDS | SRPKEHEHEG | KKRRKE

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

603055

Pfam:

PF02731

STRING:

9606.ENSP00000261531

String:

Q13573

UniGene:

Hs.445498

KEGG:

hsa:22938

Uniprot:

Q13573

FOR

ELISA Kit for Human SNW domain-containing protein 1

CLIA Kit for Human SNW domain-containing protein 1

Polyclonal Antibody for Human SNW domain-containing protein 1

Monoclonal Antibody for Human SNW domain-containing protein 1

Protein for Human SNW domain-containing protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription."
Baudino T.A. , Kraichely D.M. , Jefcoat S.C. Jr. , Winchester S.K. , Partridge N.C. , Macdonald P.N.
J. Biol. Chem.273:16434-16441(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH VDR
2.

"The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42."
Dahl R. , Wani B. , Hayman M.J.
Oncogene16:1579-1586(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBUNIT
3.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2004-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Testis.
5.

"The DNA sequence and analysis of human chromosome 14."
Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Cervix.
8.

Bienvenut W.V. , Dozynkiewicz M. , Norman J.C.
Submitted (2009-06) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-23; 82-95; 179-193 AND 401-410;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Ovarian carcinoma.
9.

"The homolog of chromatin binding protein Bx42 identified in Dictyostelium."
Folk P. , Puta F. , Krpejsova L. , Blahuskova A. , Markos A. , Rabino M. , Dottin R.P.
Gene181:229-231(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 282-536
10.

"A role for SKIP in EBNA2 activation of CBF1-repressed promoters."
Zhou S. , Fujimuro M. , Hsieh J.J. , Chen L. , Hayward S.D.
J. Virol.74:1939-1947(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH RBPJ; CIR1; HDAC2 AND EPSTEIN-BARR VIRUS EBNA2 PROTEIN
11.

"SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function."
Zhou S. , Fujimuro M. , Hsieh J.J. , Chen L. , Miyamoto A. , Weinmaster G. , Hayward S.D.
Mol. Cell. Biol.20:2400-2410(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NOTCH1
12.

"The product of an oculopharyngeal muscular dystrophy gene, poly(A)-binding protein 2, interacts with SKIP and stimulates muscle-specific gene expression."
Kim Y.-J. , Noguchi S. , Hayashi Y.K. , Tsukahara T. , Shimizu T. , Arahata K.
Hum. Mol. Genet.10:1129-1139(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PABPN1
13.

"Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription."
Leong G.M. , Subramaniam N. , Figueroa J. , Flanagan J.L. , Hayman M.J. , Eisman J.A. , Kouzmenko A.P.
J. Biol. Chem.276:18243-18248(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH SMAD2 AND SMAD3
14.

"Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription."
Zhang C. , Baudino T.A. , Dowd D.R. , Tokumaru H. , Wang W. , MacDonald P.N.
J. Biol. Chem.276:40614-40620(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
15.

"The HPV-16 E7 oncoprotein binds Skip and suppresses its transcriptional activity."
Prathapam T. , Kuhne C. , Banks L.
Oncogene20:7677-7685(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HPV16 PROTEIN E7
16.

"Skip interacts with the retinoblastoma tumor suppressor and inhibits its transcriptional repression activity."
Prathapam T. , Kuhne C. , Banks L.
Nucleic Acids Res.30:5261-5268(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RB1
17.

"Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis."
Jurica M.S. , Licklider L.J. , Gygi S.P. , Grigorieff N. , Moore M.J.
RNA8:426-439(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN THE SPLICEOSOMAL C COMPLEX
18.

"Interactions of SKIP/NCoA-62, TFIIB, and retinoid X receptor with vitamin D receptor helix H10 residues."
Barry J.B. , Leong G.M. , Church W.B. , Issa L.L. , Eisman J.A. , Gardiner E.M.
J. Biol. Chem.278:8224-8228(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH VDR
19.

"Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing."
Zhang C. , Dowd D.R. , Staal A. , Gu C. , Lian J.B. , van Wijnen A.J. , Stein G.S. , MacDonald P.N.
J. Biol. Chem.278:35325-35336(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;SUBCELLULAR LOCATION
20.

"Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300."
Leong G.M. , Subramaniam N. , Issa L.L. , Barry J.B. , Kino T. , Driggers P.H. , Hayman M.J. , Eisman J.A. , Gardiner E.M.
Biochem. Biophys. Res. Commun.315:1070-1076(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
21.

"MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription."
Laduron S. , Deplus R. , Zhou S. , Kholmanskikh O. , Godelaine D. , De Smet C. , Hayward S.D. , Fuks F. , Boon T. , De Plaen E.
Nucleic Acids Res.32:4340-4350(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MAGEA1
22.

"The human Ski-interacting protein functionally substitutes for the yeast PRP45 gene."
Figueroa J.D. , Hayman M.J.
Biochem. Biophys. Res. Commun.319:1105-1109(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
23.

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
24.

"Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP."
Xu C. , Zhang J. , Huang X. , Sun J. , Xu Y. , Tang Y. , Wu J. , Shi Y. , Huang Q. , Zhang Q.
J. Biol. Chem.281:15900-15908(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PPIL1
25.

"CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor."
Scott K.L. , Plon S.E.
Gene359:119-126(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FOXN3
26.

"A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat."
Bres V. , Gomes N. , Pickle L. , Jones K.A.
Genes Dev.19:1211-1226(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
27.

"Regulation of cyclin D1 RNA stability by SNIP1."
Bracken C.P. , Wall S.J. , Barre B. , Panov K.I. , Ajuh P.M. , Perkins N.D.
Cancer Res.68:7621-7628(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE SNARP COMPLEX
28.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-224 AND SER-232;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
29.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
30.

"SKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivation."
Bres V. , Yoshida T. , Pickle L. , Jones K.A.
Mol. Cell36:75-87(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
31.

"A large intrinsically disordered region in SKIP and its disorder- order transition induced by PPIL1 binding revealed by NMR."
Wang X. , Zhang S. , Zhang J. , Huang X. , Xu C. , Wang W. , Liu Z. , Wu J. , Shi Y.
J. Biol. Chem.285:4951-4963(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PPIL;MUTAGENESIS OF GLU-66 AND MET-76
32.

"The crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP protein."
Stegmann C.M. , Luhrmann R. , Wahl M.C.
PLoS ONE5:E10013-E10013(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PPIL
33.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-224; SER-232 AND SER-234;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
34.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
35.

"SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing."
Chen Y. , Zhang L. , Jones K.A.
Genes Dev.25:701-716(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH U2AF2
36.

"Assembly of a Notch transcriptional activation complex requires multimerization."
Vasquez-Del Carpio R. , Kaplan F.M. , Weaver K.L. , VanWye J.D. , Alves-Guerra M.C. , Robbins D.J. , Capobianco A.J.
Mol. Cell. Biol.31:1396-1408(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH NOTCH1 AND MAML1
37.

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-224 AND SER-234;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
38.

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
39.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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