SLCO1A2 ELISA Kit for Human(Homo sapiens) | EIAab.comSLCO1A2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > SLCO1A2(Gene name) > Human

SLCO1A2 (Gene name),

Solute carrier organic anion transporter family member 1A2 (Protein name ), SO1A2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

SLCO1A2(OATP;OATP1;OATP1A2;SLC21A3);

Protein name:

Solute carrier organic anion transporter family member 1A2;

Alternative:

Organic anion-transporting polypeptide 1(OATP-1);OATP-A;Solute carrier family 21 member 3;Sodium-independent organic anion transporter;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

670

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

670:

CKDIYQKSTV | LKDDELKTKL |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P46721

Pfam:

PF07648

STRING:

9606.ENSP00000305974

KEGG:

hsa:6579

String:

P46721

UniGene:

Hs.46440

MIM:

602883

Uniprot:

P46721

FOR

ELISA Kit for Human Solute carrier organic anion transporter family member 1A2

CLIA Kit for Human Solute carrier organic anion transporter family member 1A2

Polyclonal Antibody for Human Solute carrier organic anion transporter family member 1A2

Monoclonal Antibody for Human Solute carrier organic anion transporter family member 1A2

Protein for Human Solute carrier organic anion transporter family member 1A2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular and functional characterization of an organic anion transporting polypeptide cloned from human liver."
Kullak-Ublick G.-A. , Hagenbuch B. , Stieger B. , Schteingart C.D. , Hofmann A.F. , Wolkoff A.W. , Meier P.J.
Gastroenterology109:1274-1282(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM OATP1A)
tissue: Liver.
2.

"Isolation of human neural alternative form of organic anion transporter subtype."
Abe T. , Kakyo M. , Yawo H.
Submitted (1998-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORM OATP1B)
3.

"Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide."
Koenig J. , Cui Y. , Nies A.T. , Keppler D.
J. Biol. Chem.275:23161-23168(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORM OATP1A)
4.

"Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes."
Speek M.
Mol. Cell. Biol.21:1973-1985(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORM OATP1A)
tissue: Teratocarcinoma.
5.

"Upstream region of the human organic anion transporting polypeptide A (OATP-A) gene."
Kullak-Ublick G.-A.
Submitted (1999-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 1-20
6.

"Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice."
Bailey D.G. , Dresser G.K. , Leake B.F. , Kim R.B.
Clin. Pharmacol. Ther.81:495-502(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
7.

"Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry."
Lee W. , Glaeser H. , Smith L.H. , Roberts R.L. , Moeckel G.W. , Gervasini G. , Leake B.F. , Kim R.B.
J. Biol. Chem.280:9610-9617(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS THR-13; TYR-128; ILE-135; ASP-172; THR-187 AND SER-668
8.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ILE-220

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