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Index > Protein center > Slco1a4(Gene name) > Rat
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  • Slco1a4 (Gene name),
  • Solute carrier organic anion transporter family member 1A4 (Protein name ),  SO1A4_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slco1a4(Oatp1a4;Oatp2;Slc21a5);
    Protein name:
    Solute carrier organic anion transporter family member 1A4;
    Alternative:
    Brain-specific organic anion transporter;Brain digoxin carrier protein;Sodium-independent organic anion-transporting polypeptide 2;OATP-B1;Solute carrier family 21 member 5;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Mediates the Na(+)-independent transport of organic anions such as taurocholate, cholate, 17-beta-glucuronosyl estradiol, estrone-3-sulfate, the cardiac glycosides ouabain and digoxin and thyroid hormones. May play an especially important role in the brain accumulation and toxicity of digoxin and in the hepatobiliary and renal excretion of cardiac glycosides.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    661
    Sequence:
    50:
    MGKSEKRVAT | HGVRCFAKIK | MFLLALTCAY | VSKSLSGTYM | NSMLTQIERQ | 
    100:
    FGIPTSIVGL | INGSFEIGNL | LLIIFVSYFG | TKLHRPIMIG | VGCAVMGLGC | 
    150:
    FLISLPHFLM | GQYEYETILP | TSNVSSNSFF | CVENRSQTLN | PTQDPSECVK | 
    200:
    EMKSLMWIYV | LVGNIIRGIG | ETPIMPLGIS | YIEDFAKSEN | SPLYIGILET | 
    250:
    GMTIGPLIGL | LLASSCANIY | VDIESVNTDD | LTITPTDTRW | VGAWWIGFLV | 
    300:
    CAGVNILTSF | PFFFFPKTLP | KEGLQENVDG | TENAKEKKHR | KKAKEEKRGI | 
    350:
    TKDFFVFMKS | LSCNPIYMLF | ILISVLQFNA | FINSFTFMPK | YLEQQYGKST | 
    400:
    AEVVFLMGLY | MLPPICLGYL | IGGLIMKKFK | VTVKKAAHLA | FWLCLSEYLL | 
    450:
    SFLSYVMTCD | NFPVAGLTTS | YEGVQHQLYV | ENKVLADCNT | RCNCSTNTWD | 
    500:
    PVCGDNGLAY | MSACLAGCEK | SVGTGTNMVF | QNCSCIQSSG | NSSAVLGLCN | 
    550:
    KGPDCANKLQ | YFLIIAIFGC | FIYSLAGIPG | YMVLLRCIKS | EEKSLGVGLH | 
    600:
    AFCIRILAGI | PAPIYFGALI | DRTCLHWGTL | KCGEPGACRM | YDINSFRRLY | 
    650:
    LGLPAALRGA | SFVPAFFILR | LTRTFQFPGD | IESSKTDHAE | MKLTLKESEC | 
    661:
    TEVLRSKVTE | D
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Solute carrier organic anion transporter family member 1A4
    ELISA Kit for Rat Solute carrier organic anion transporter family member 1A4
    CLIA Kit for Rat Solute carrier organic anion transporter family member 1A4
    CLIA Kit for Rat Solute carrier organic anion transporter family member 1A4
    Polyclonal Antibody for Rat Solute carrier organic anion transporter family member 1A4
    Polyclonal Antibody for Rat Solute carrier organic anion transporter family member 1A4
    Monoclonal Antibody for Rat Solute carrier organic anion transporter family member 1A4
    Monoclonal Antibody for Rat Solute carrier organic anion transporter family member 1A4
    Protein for Rat Solute carrier organic anion transporter family member 1A4
    Protein for Rat Solute carrier organic anion transporter family member 1A4

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain."
      Noe B. , Hagenbuch B. , Stieger B. , Meier P.J.
      Proc. Natl. Acad. Sci. U.S.A.94:10346-10350(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Brain.
    2. 2.
      "Molecular characterization and tissue distribution of a new organic anion transporter subtype (oatp3) that transports thyroid hormones and taurocholate and comparison with oatp2."
      Abe T. , Kakyo M. , Sakagami H. , Tokui T. , Nishio T. , Tanemoto M. , Nomura H. , Hebert S.C. , Matsuno S. , Kondo H. , Yawo H.
      J. Biol. Chem.273:22395-22401(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Retina.
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