Protein name:
Sclerostin;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling.
Function:
Negative regulator of bone growth.
Subcellular Location:
Secreted
Protein Attributes:
50:
MQPSLAPCLI | CLLVHAAFCA | VEGQGWQAFR | NDATEVIPGL | GEYPEPPPEN |
100:
NQTMNRAENG | GRPPHHPYDA | KGVSEYSCRE | LHYTRFLTDG | PCRSAKPVTE |
150:
LVCSGQCGPA | RLLPNAIGRV | KWWRPNGPDF | RCIPDRYRAQ | RVQLLCPGGA |
200:
APRSRKVRLV | ASCKCKRLTR | FHNQSELKDF | GPETARPQKG | RKPRPGARGA |

Vaild Sequence:
Related Databases
Uniprot:
FOR
ELISA Kit for Mouse Sclerostin
ELISA Kit for Mouse Sclerostin
ELISA Kit for Mouse Sclerostin
ELISA Kit for Mouse Sclerostin
CLIA Kit for Mouse Sclerostin
CLIA Kit for Mouse Sclerostin
CLIA Kit for Mouse Sclerostin
CLIA Kit for Mouse Sclerostin
Polyclonal Antibody for Mouse Sclerostin
Polyclonal Antibody for Mouse Sclerostin
Polyclonal Antibody for Mouse Sclerostin
Polyclonal Antibody for Mouse Sclerostin
Monoclonal Antibody for Mouse Sclerostin
Monoclonal Antibody for Mouse Sclerostin
Monoclonal Antibody for Mouse Sclerostin
Monoclonal Antibody for Mouse Sclerostin
Protein for Mouse Sclerostin
Protein for Mouse Sclerostin
Protein for Mouse Sclerostin
Protein for Mouse Sclerostin

R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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1.
"Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein."
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Am. J. Hum. Genet.68:577-589(2001)
[
PubMed]
[
Europe PMC]
[
Abstract]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
strain:
129/SvJ.
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2.
"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed]
[
Europe PMC]
[
Abstract]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain:
C57BL/6J.
tissue:
Head.
-
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: INTERACTION WITH LRP5 AND LRP6
-
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: FUNCTION;DISRUPTION PHENOTYPE
-
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: STRUCTURE BY NMR OF 59-167;DISULFIDE BONDS