Gene name:
SV2A (PSEC0174;KIAA0736) ;
Protein name:
Synaptic vesicle glycoprotein 2A ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with SYT1/synaptotagmin-1 in a calcium-dependent manner. Binds the adapter protein complex AP-2.
Function:
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles.
Subcellular Location:
Cytoplasmic vesicle
secretory vesicle
synaptic vesicle membrane
Multi-pass membrane protein
Enriched in chromaffin granules, not present in adrenal microsomes. Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas.
Protein Attributes:
50:
MEEGFRDRAA | FIRGAKDIAK | EVKKHAAKKV | VKGLDRVQDE | YSRRSYSRFE |
100:
EEDDDDDFPA | PSDGYYRGEG | TQDEEEGGAS | SDATEGHDED | DEIYEGEYQG |
150:
IPRAESGGKG | ERMADGAPLA | GVRGGLSDGE | GPPGGRGEAQ | RRKEREELAQ |
200:
QYEAILRECG | HGRFQWTLYF | VLGLALMADG | VEVFVVGFVL | PSAEKDMCLS |
250:
DSNKGMLGLI | VYLGMMVGAF | LWGGLADRLG | RRQCLLISLS | VNSVFAFFSS |
300:
FVQGYGTFLF | CRLLSGVGIG | GSIPIVFSYF | SEFLAQEKRG | EHLSWLCMFW |
350:
MIGGVYAAAM | AWAIIPHYGW | SFQMGSAYQF | HSWRVFVLVC | AFPSVFAIGA |
400:
LTTQPESPRF | FLENGKHDEA | WMVLKQVHDT | NMRAKGHPER | VFSVTHIKTI |
450:
HQEDELIEIQ | SDTGTWYQRW | GVRALSLGGQ | VWGNFLSCFG | PEYRRITLMM |
500:
MGVWFTMSFS | YYGLTVWFPD | MIRHLQAVDY | ASRTKVFPGE | RVEHVTFNFT |
550:
LENQIHRGGQ | YFNDKFIGLR | LKSVSFEDSL | FEECYFEDVT | SSNTFFRNCT |
600:
FINTVFYNTD | LFEYKFVNSR | LINSTFLHNK | EGCPLDVTGT | GEGAYMVYFV |
650:
SFLGTLAVLP | GNIVSALLMD | KIGRLRMLAG | SSVMSCVSCF | FLSFGNSESA |
700:
MIALLCLFGG | VSIASWNALD | VLTVELYPSD | KRTTAFGFLN | ALCKLAAVLG |
742:
ISIFTSFVGI | TKAAPILFAS | AALALGSSLA | LKLPETRGQV | LQ
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Bovine
Mouse
ELISA Kit for Human Synaptic vesicle glycoprotein 2A
ELISA Kit for Human Synaptic vesicle glycoprotein 2A
ELISA Kit for Human Synaptic vesicle glycoprotein 2A
ELISA Kit for Human Synaptic vesicle glycoprotein 2A
CLIA Kit for Human Synaptic vesicle glycoprotein 2A
CLIA Kit for Human Synaptic vesicle glycoprotein 2A
CLIA Kit for Human Synaptic vesicle glycoprotein 2A
CLIA Kit for Human Synaptic vesicle glycoprotein 2A
Polyclonal Antibody for Human Synaptic vesicle glycoprotein 2A
Polyclonal Antibody for Human Synaptic vesicle glycoprotein 2A
Polyclonal Antibody for Human Synaptic vesicle glycoprotein 2A
Polyclonal Antibody for Human Synaptic vesicle glycoprotein 2A
Monoclonal Antibody for Human Synaptic vesicle glycoprotein 2A
Monoclonal Antibody for Human Synaptic vesicle glycoprotein 2A
Monoclonal Antibody for Human Synaptic vesicle glycoprotein 2A
Monoclonal Antibody for Human Synaptic vesicle glycoprotein 2A
Protein for Human Synaptic vesicle glycoprotein 2A
Protein for Human Synaptic vesicle glycoprotein 2A
Protein for Human Synaptic vesicle glycoprotein 2A
Protein for Human Synaptic vesicle glycoprotein 2A
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Brain .
tissue :
Ovary .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION AS BINDING-SITE FOR ANTIEPILEPTIC DRUG LEVETIRACETAM
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-80; SER-81 AND THR-84;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .