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Index > Protein center > Snca(Gene name) > Rat
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  • Snca (Gene name),
  • Alpha-synuclein (Protein name ),  SYUA_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Snca;
    Protein name:
    Alpha-synuclein;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with UCHL1.
    Function:
    May be involved in the regulation of dopamine release and transport.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    140
    Sequence:
    50:
    MDVFMKGLSK | AKEGVVAAAE | KTKQGVAEAA | GKTKEGVLYV | GSKTKEGVVH | 
    100:
    GVTTVAEKTK | EQVTNVGGAV | VTGVTAVAQK | TVEGAGNIAA | ATGFVKKDQM | 
    140:
    GKGEEGYPQE | GILEDMPVDP | SSEAYEMPSE | EGYQDYEPEA | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    SMR:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Alpha-synuclein
    Cat.:
    E1222m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Alpha-synuclein
    Cat.:
    E1222r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Alpha-synuclein
    Cat.:
    E1222h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Alpha-synuclein
    Cat.:
    E1222b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Alpha-synuclein
    Cat.:
    E1222p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Alpha-synuclein
    Cat.:
    U1222b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Alpha-synuclein
    Cat.:
    U1222h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Alpha-synuclein
    Cat.:
    U1222r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Alpha-synuclein
    Cat.:
    U1222p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Alpha-synuclein
    Cat.:
    U1222m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Alpha-synuclein
    Cat.:
    P1222Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Alpha-synuclein
    Cat.:
    P1222Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Alpha-synuclein
    Cat.:
    P1222Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Alpha-synuclein
    Polyclonal Antibody for Rat Alpha-synuclein
    Monoclonal Antibody for Rat Alpha-synuclein
    Monoclonal Antibody for Rat Alpha-synuclein
    Monoclonal Antibody for Rat Alpha-synuclein
    Monoclonal Antibody for Rat Alpha-synuclein
    Monoclonal Antibody for Rat Alpha-synuclein
    Protein for Rat Alpha-synuclein
    Protein for Rat Alpha-synuclein
    Protein for Rat Alpha-synuclein
    Protein for Rat Alpha-synuclein
    Protein for Rat Alpha-synuclein

    R&D Technical Data
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         12% SDS-PAGE Analysis

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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤ 3.7%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤ 6.1%

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    Recovery
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    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    94

    91-98

    Plasma

    93

    93-99

     

     

     

     

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    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    92-96%

    90-99%

    91-101%

    92-104%

    EDTA plasma(n=5)

    89-95%

    93-101%

    89-94%

    90-102%

    heparin plasma(n=5)

    93-102%

     

    94-103%

    96-102%

    91-101%

     

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    References
    1. 1.
      "The rat brain synucleins; family of proteins transiently associated with neuronal membrane."
      Maroteaux L. , Scheller R.H.
      Brain Res. Mol. Brain Res.11:335-343(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING
      tissue: Brain.
    2. 2.
      "Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal."
      Maroteaux L. , Campanelli J.T. , Scheller R.H.
      J. Neurosci.8:2804-2815(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SYN2)
    3. 3.
      "Increased expression of rat synuclein in the substantia nigra pars compacta identified by mRNA differential display in a model of developmental target injury."
      Kholodilov N.G. , Neystat M. , Oo T.F. , Lo S.E. , Larsen K.E. , Sulzer D. , Burke R.E.
      J. Neurochem.73:2586-2599(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SYN1)
    4. 4.
      "Alpha-synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats."
      Liang T. , Spence J. , Liu L. , Strother W.N. , Chang H.W. , Ellison J.A. , Lumeng L. , Li T.K. , Foroud T. , Carr L.G.
      Proc. Natl. Acad. Sci. U.S.A.100:4690-4695(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SYN1)
      strain: Wistar.
      tissue: Brain.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM SYN1)
      tissue: Brain.
    6. 6.
      Lubec G. , Chen W.-Q.
      Submitted (2007-04) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 33-97;IDENTIFICATION BY MASS SPECTROMETRY
      strain: Sprague-Dawley.
      tissue: Hippocampus.
    7. 7.
      "The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility."
      Liu Y. , Fallon L. , Lashuel H.A. , Liu Z. , Lansbury P.T. Jr.
      Cell111:209-218(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UBIQUITINATION;INTERACTION WITH UCHL1
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