Gene name:
VARS2 (KIAA1885;VARS2L;VARSL) ;
Protein name:
Valyl-tRNA synthetase, mitochondrial ;
Alternative:
Valyl-tRNA synthetase-like ;Valine--tRNA ligase (ValRS) ;
Organism:
Human (Homo sapiens).
General Annotation
Subcellular Location:
Mitochondrion
Protein Attributes:
50:
MPHLPLASFR | PPFWGLRHSR | GLPRFHSVST | QSEPHGSPIS | RRNREAKQKR |
100:
LREKQATLEA | EIAGESKSPA | ESIKAWRPKE | LVLYEIPTKP | GEKKDVSGPL |
150:
PPAYSPRYVE | AAWYPWWVRE | GFFKPEYQAR | LPQATGETFS | MCIPPPNVTG |
200:
SLHIGHALTV | AIQDALVRWH | RMRGDQVLWV | PGSDHAGIAT | QAVVEKQLWK |
250:
ERGVRRHELS | REAFLREVWQ | WKEAKGGEIC | EQLRALGASL | DWDRECFTMD |
300:
VGSSVAVTEA | FVRLYKAGLL | YRNHQLVNWS | CALRSAISDI | EVENRPLPGH |
350:
TQLRLPGCPT | PVSFGLLFSV | AFPVDGEPDA | EVVVGTTRPE | TLPGDVAVAV |
400:
HPDDSRYTHL | HGRQLRHPLM | GQPLPLITDY | AVQPHVGTGA | VKVTPAHSPA |
450:
DAEMGARHGL | SPLNVIAEDG | TMTSLCGDWL | QGLHRFVARE | KIMSVLSEWG |
500:
LFRGLQNHPM | VLPICSRSGD | VIEYLLKNQW | FVRCQEMGAR | AAKAVESGAL |
550:
ELSPSFHQKN | WQHWFSHIGD | WCVSRQLWWG | HQIPAYLVVE | DHAQGEEDCW |
600:
VVGRSEAEAR | EVAAELTGRP | GAELTLERDP | DVLDTWFSSA | LFPFSALGWP |
650:
QETPDLARFY | PLSLLETGSD | LLLFWVGRMV | MLGTQLTGQL | PFSKVLLHPM |
700:
VRDRQGRKMS | KSLGNVLDPR | DIISGVEMQV | LQEKLRSGNL | DPAELAIVAA |
750:
AQKKDFPHGI | PECGTDALRF | TLCSHGVQAG | DLHLSVSEVQ | SCRHFCNKIW |
800:
NALRFILNAL | GEKFVPQPAE | ELSPSSPMDA | WILSRLALAA | QECERGFLTR |
850:
ELSLVTHALH | HFWLHNLCDV | YLEAVKPVLW | HSPRPLGPPQ | VLFSCADLGL |
900:
RLLAPLMPFL | AEELWQRLPP | RPGCPPAPSI | SVAPYPSACS | LEHWRQPELE |
950:
RRFSRVQEVV | QVLRALRATY | QLTKARPRVL | LQSSEPGDQG | LFEAFLEPLG |
1000:
TLGYCGAVGL | LPPGAAAPSG | WAQAPLSDTA | QVYMELQGLV | DPQIQLPLLA |
1050:
ARRYKLQKQL | DSLTARTPSE | GEAGTQRQQK | LSSLQLELSK | LDKAASHLRQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Pig
Human
Mouse
ELISA Kit for Human Valyl-tRNA synthetase, mitochondrial
ELISA Kit for Human Valyl-tRNA synthetase, mitochondrial
ELISA Kit for Human Valyl-tRNA synthetase, mitochondrial
ELISA Kit for Human Valyl-tRNA synthetase, mitochondrial
CLIA Kit for Human Valyl-tRNA synthetase, mitochondrial
CLIA Kit for Human Valyl-tRNA synthetase, mitochondrial
CLIA Kit for Human Valyl-tRNA synthetase, mitochondrial
CLIA Kit for Human Valyl-tRNA synthetase, mitochondrial
Polyclonal Antibody for Human Valyl-tRNA synthetase, mitochondrial
Polyclonal Antibody for Human Valyl-tRNA synthetase, mitochondrial
Polyclonal Antibody for Human Valyl-tRNA synthetase, mitochondrial
Polyclonal Antibody for Human Valyl-tRNA synthetase, mitochondrial
Monoclonal Antibody for Human Valyl-tRNA synthetase, mitochondrial
Monoclonal Antibody for Human Valyl-tRNA synthetase, mitochondrial
Monoclonal Antibody for Human Valyl-tRNA synthetase, mitochondrial
Monoclonal Antibody for Human Valyl-tRNA synthetase, mitochondrial
Protein for Human Valyl-tRNA synthetase, mitochondrial
Protein for Human Valyl-tRNA synthetase, mitochondrial
Protein for Human Valyl-tRNA synthetase, mitochondrial
Protein for Human Valyl-tRNA synthetase, mitochondrial
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT GLN-1049
tissue :
Brain .
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3 AND 4);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 416-1063 (ISOFORM 1);VARIANTS ARG-449; LEU-680; GLN-917 AND THR-965
tissue :
Cerebellum .
tissue :
Thalamus .
tissue :
Uterus .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS ARG-449; LEU-680 AND THR-965
tissue :
Brain .
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[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANTS ARG-449; LEU-680; GLN-917; THR-965 AND GLN-1049
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS ARG-449; LEU-680; GLN-917; THR-965 AND GLN-1049
tissue :
Brain .
tissue :
Eye .
tissue :
Skin .
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more...
BMC Genomics8:399-399(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 748-1063 (ISOFORM 1);VARIANT THR-965
tissue :
Testis .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.
"VARS2 and TARS2 mutations in patients with mitochondrial encephalomyopathies."
Diodato D.
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more...
Hum. Mutat.35:983-989(2014)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : INVOLVEMENT IN COXPD20;VARIANT COXPD20 ILE-337;CHARACTERIZATION OF VARIANT COXPD20 ILE-337
9.
"Use of whole-exome sequencing to determine the genetic basis of multiple mitochondrial respiratory chain complex deficiencies."
Taylor R.W.
,
Pyle A.
,
Griffin H.
,
Blakely E.L.
,
Duff J.
,
He L.
,
Smertenko T.
,
Alston C.L.
,
Neeve V.C.
,
Best A.
,
Yarham J.W.
,
Kirschner J.
,
Schara U.
,
Talim B.
,
Topaloglu H.
,
Baric I.
,
Holinski-Feder E.
,
Abicht A.
,
Czermin B.
,
Kleinle S.
,
Morris A.A.
,
Vassallo G.
,
Gorman G.S.
,
Ramesh V.
,
Turnbull D.M.
,
Santibanez-Koref M.
,
McFarland R.
,
Horvath R.
,
Chinnery P.F.
more...
JAMA312:68-77(2014)
[
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Europe PMC ]
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Abstract ]
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Cited for : VARIANTS COXPD20 THR-349 AND ASP-596