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Index > Protein center > Wars(Gene name) > Mouse
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  • Wars (Gene name),
  • Tryptophanyl-tRNA synthetase, cytoplasmic (Protein name ),  SYWC_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Wars(Wrs);
    Protein name:
    Tryptophanyl-tRNA synthetase, cytoplasmic;
    Alternative:
    Tryptophan--tRNA ligase(TrpRS);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with oxidized form of GAPDH.
    Function:
    T1-TrpRS has aminoacylation activity while T2-TrpRS lacks it. T1-TrpRS and T2-TrpRS possess angiostatic activity. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    481
    Sequence:
    50:
    MADMPSGESC | TSPLELFNSI | ATQGELVRSL | KAGNAPKDEI | DSAVKMLLSL | 
    100:
    KMSYKAAMGE | EYKAGCPPGN | PTAGRNCDSD | ATKASEDFVD | PWTVRTSSAK | 
    150:
    GIDYDKLIVQ | FGSSKIDKEL | INRIERATGQ | RPHRFLRRGI | FFSHRDMNQI | 
    200:
    LDAYENKKPF | YLYTGRGPSS | EAMHLGHLVP | FIFTKWLQDV | FNVPLVIQMS | 
    250:
    DDEKYLWKDL | TLEQAYSYTV | ENAKDIIACG | FDINKTFIFS | DLEYMGQSPG | 
    300:
    FYRNVVKIQK | HVTFNQVKGI | FGFTDSDCIG | KISFPAVQAA | PSFSNSFPKI | 
    350:
    FRDRTDIQCL | IPCAIDQDPY | FRMTRDVAPR | IGHPKPALLH | STFFPALQGA | 
    400:
    QTKMSASDPN | SSIFLTDTAK | QIKSKVNKHA | FSGGRDTVEE | HRQFGGNCEV | 
    450:
    DVSFMYLTFF | LEDDDRLEQI | RKDYTSGAML | TGELKKTLID | VLQPLIAEHQ | 
    481:
    ARRKAVTEET | VKEFMTPRQL | SFHFQCFCFD | T
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
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    E1748b
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    ELISA Kit for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
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    E1748m
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    ELISA Kit for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
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    E1748h
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    ELISA Kit for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Cat.:
    E1748r
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    Packing:
    96T
    ELISA Kit for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
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    CLIA Kit for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Cat.:
    U1748m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Cat.:
    U1748r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Cat.:
    U1748b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Cat.:
    U1748h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Cat.:
    P1748Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Cat.:
    P1748Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Polyclonal Antibody for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Cat.:
    P1748Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Monoclonal Antibody for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Monoclonal Antibody for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Monoclonal Antibody for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Monoclonal Antibody for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Monoclonal Antibody for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Protein for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Protein for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Protein for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Protein for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic
    Protein for Mouse Tryptophanyl-tRNA synthetase, cytoplasmic

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "An alternative splicing modifies the C-terminal end of tryptophanyl-tRNA synthetase in murine embryonic stem cells."
      Pajot B. , Sarger C. , Bonnet J. , Garret M.
      J. Mol. Biol.242:599-603(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Lung.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6.
      strain: NMRI.
      tissue: Brain.
      tissue: Mammary tumor.
    4. 4.
      Lubec G. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 38-45; 56-63; 84-95; 107-123; 146-166; 186-204; 209-253; 269-299; 331-370; 423-436 AND 437-452;IDENTIFICATION BY MASS SPECTROMETRY
      strain: OF1.
      tissue: Hippocampus.
    5. 5.
      "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
      Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-158;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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