Protein name:
Tryptophanyl-tRNA synthetase, cytoplasmic ;
Alternative:
Tryptophan--tRNA ligase (TrpRS) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homodimer. Interacts with oxidized form of GAPDH.
Function:
T1-TrpRS has aminoacylation activity while T2-TrpRS lacks it. T1-TrpRS and T2-TrpRS possess angiostatic activity. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MADMPSGESC | TSPLELFNSI | AAQGELVRSL | KAGNAPKDEI | ESAVKMLLSL |
100:
KMNYKTAMGE | EYKAGCPPGN | STAGSNGDPD | ATKASEDFVD | PWTVRTSSAK |
150:
GIDYDKLIVQ | FGSSKIDKEL | INRIERATGQ | RPHRFLRRGI | FFSHRDMNQI |
200:
LDAYENKKPF | YLYTGRGPSS | EAMHLGHLVP | FIFTKWLQDV | FDVPLVIQMS |
250:
DDEKYLWKDL | TLEQAYSYTV | ENAKDIIACG | FDVNKTFIFS | DLEYMGQSPG |
300:
FYKNVVKIQK | HVTFNQVKGI | FGFTDSDCIG | KISFPAVQAA | PSFSNSFPKI |
350:
FRDRTDIQCL | IPCAIDQDPY | FRMTRDVAPR | IGHPKPALLH | STFFPALQGA |
400:
QTKMSASDPN | SSIFLTDTAK | QIKSKVNKHA | FSGGRDTVEE | HRQFGGNCEV |
450:
DVSFMYLTFF | LEDDDSLEQI | RKDYTSGAML | TGELKKTLID | VLQPLIAEHQ |
481:
ARRKAVTEET | VKEFMAPRQL | SFHFQCFCFD | T
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Human
Rat
Rabbit
ELISA Kit for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
ELISA Kit for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
ELISA Kit for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
ELISA Kit for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
ELISA Kit for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
CLIA Kit for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
CLIA Kit for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
CLIA Kit for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
CLIA Kit for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
CLIA Kit for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Polyclonal Antibody for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Polyclonal Antibody for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Polyclonal Antibody for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Polyclonal Antibody for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Polyclonal Antibody for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Monoclonal Antibody for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Monoclonal Antibody for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Monoclonal Antibody for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Monoclonal Antibody for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Monoclonal Antibody for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Protein for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Protein for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Protein for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Protein for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
Protein for Rat Tryptophanyl-tRNA synthetase, cytoplasmic
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
Soares M.B.
,
Casavant T.L.
,
Sheffield V.C.
,
Bonaldo M.F.
,
Bair T.B.
,
Scheetz T.E.
,
Snir E.
,
Akabogu I.
,
Bair J.L.
,
Berger B.
,
Crouch K.
,
Davis A.
,
Eystone M.E.
,
Keppel C.
,
Kucaba T.A.
,
Lebeck M.
,
Lin J.L.
,
de Melo A.I.R.
,
Rehmann J.
,
Reiter R.S.
,
Schaefer K.
,
Smith C.
,
Tack D.
,
Trout K.
,
Lin J.J.-C.
more...
Submitted (2004-08) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-473
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 38-424
tissue :
Prostate .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 429-481
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 269-299 AND 331-353;IDENTIFICATION BY MASS SPECTROMETRY
strain :
Sprague-Dawley .
tissue :
Spinal cord .