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Index > Protein center > Tap2(Gene name) > Rat
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  • Tap2 (Gene name),
  • Antigen peptide transporter 2 (Protein name ),  TAP2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Tap2(Abcb3;Mtp2);
    Protein name:
    Antigen peptide transporter 2(APT2);
    Alternative:
    ATP-binding cassette sub-family B member 3;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Heterodimer of TAP1 and TAP2.
    Function:
    Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein The transmembrane segments seem to form a pore in the membrane.
    Protein Attributes:
    Sequence length:
    703
    Sequence:
    50:
    MALSHPRPWA | SLLLVDLALL | GLLQSSLGTL | LPPGLPGLWL | EGTLRLGVLW | 
    100:
    GLLKVGGLLR | LVGTFLPLLC | LTNPLFFSLR | ALVGSTMSTS | VVRVASASWG | 
    150:
    WLLADYGAVA | LSLAVWAVLS | PAGAQEKEPG | QENNRALMIR | LLRLSKPDLP | 
    200:
    FLIVAFIFLA | MAVWWEMFIP | HYSGRVIDIL | GGDFDPDAFA | SAIFFMCLFS | 
    250:
    VGSSLSAGCR | GGSFLFAESR | INLRIREQLF | SSLLRQDLAF | FQETKTGELN | 
    300:
    SRLSSDTSLM | SQWLSLNANI | LLRSLVKVVG | LYYFMLQVSP | RLTFLSLLDL | 
    350:
    PLTIAAEKVY | NPRHQAVLKE | IQDAVAKAGQ | VVREAVGGLQ | TVRSFGAEEQ | 
    400:
    EVRRYKEALE | RCRQLWWRRD | LEKSLYLVIQ | RVMALGMQVL | ILNVGVQQIL | 
    450:
    AGEVTRGGLL | SFLLYQEEVG | HHVQNLVYMY | GDMLSNVGAA | EKVFSYLDRR | 
    500:
    PNLPNPGTLA | PPRLEGRVEF | QDVSFSYPSR | PEKPVLQGLT | FTLHPGKVTA | 
    550:
    LVGPNGSGKS | TVAALLQNLY | QPTGGQLLLD | GEPLVQYDHH | YLHRQVVLVG | 
    600:
    QEPVLFSGSV | KDNIAYGLRD | CEDAQVMAAA | QAACADDFIG | EMTNGINTEI | 
    650:
    GEKGSQLAVG | QKQRLAIARA | LVRNPRVLIL | DEATSALDAE | CEQALQTWRS | 
    700:
    QEDRTMLVIA | HRLHTVQNAD | QVLVLKQGQL | VEHDQLRDEQ | DVYAHLVQQR | 
    703:
    LEA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat APT2
    Cat.:
    E10018h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat APT2
    Cat.:
    E10018m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat APT2
    Cat.:
    E10018r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat APT2
    Cat.:
    U10018h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat APT2
    Cat.:
    U10018m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat APT2
    Cat.:
    U10018r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat APT2
    Cat.:
    P10018Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat APT2
    Cat.:
    P10018Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat APT2
    Cat.:
    P10018Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat APT2
    Monoclonal Antibody for Rat APT2
    Monoclonal Antibody for Rat APT2
    Protein for Rat APT2
    Protein for Rat APT2
    Protein for Rat APT2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter."
      Powis S.J. , Townsend A.R.M. , Deverson E.V. , Bastin J. , Butcher G.W. , Howard J.C.
      Nature354:528-531(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule."
      Powis S.J. , Deverson E.V. , Coadwell W.J. , Ciruela A. , Huskisson N.S. , Smith H. , Butcher G.W. , Howard J.C.
      Nature357:211-215(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS TAP2L PHE-352 AND ARG-603
    3. 3.
      "The distribution of Tap2 alleles among laboratory rat RT1 haplotypes."
      Joly E. , Deverson E.V. , Coadwell W.L. , Guenther E. , Howard J.C. , Butcher G.W.
      Immunogenetics40:45-53(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: PVG-RT1L(LEW).
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