MAPT ELISA Kit for Bovine(Bos taurus) | EIAab.comMAPT ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > MAPT(Gene name) > Bovine

MAPT (Gene name),

Microtubule-associated protein tau (Protein name ), TAU_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MAPT(TAU);

Protein name:

Microtubule-associated protein tau;

Alternative:

Paired helical filament-tau(PHF-tau);Neurofibrillary tangle protein;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Interacts with SQSTM1 when polyubiquitinated. Interacts with PSMC2 through SQSTM1 (By similarity). Interacts with FKBP4.

Function:

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Subcellular Location:

Cytoplasm cytosol Cell membrane Peripheral membrane protein Cytoplasmic side Cytoplasm cytoskeleton Cell projection axon Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.

Protein Attributes:

Sequence length:

448

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

448:

YKSPVVSGDT | SPRHLSNVSS | TGSIDMVDSP | QLATLADEVS | ASLAKQGL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00418

KEGG:

bta:281296

String:

P29172

UniGene:

Bt.34217

Uniprot:

P29172

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ELISA Kit for Bovine Microtubule-associated protein tau

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E1983h

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96T

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ELISA Kit for Bovine Microtubule-associated protein tau

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E1983r

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96T

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ELISA Kit for Bovine Microtubule-associated protein tau

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E1983m

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96T

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ELISA Kit for Bovine Microtubule-associated protein tau

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E1983b

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96T

CLIA Kit for Bovine Microtubule-associated protein tau

Cat.:

U1983h

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96T

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CLIA Kit for Bovine Microtubule-associated protein tau

Cat.:

U1983m

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96T

CLIA Kit for Bovine Microtubule-associated protein tau

Cat.:

U1983b

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96T

CLIA Kit for Bovine Microtubule-associated protein tau

Cat.:

U1983r

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96T

Polyclonal Antibody for Bovine Microtubule-associated protein tau

Cat.:

P1983Rb-r

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40ug/0.2ml

Polyclonal Antibody for Bovine Microtubule-associated protein tau

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P1983Rb-m

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40ug/0.2ml

Polyclonal Antibody for Bovine Microtubule-associated protein tau

Cat.:

P1983Rb-h

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40ug/0.2ml

Monoclonal Antibody for Bovine Microtubule-associated protein tau

Protein for Bovine Microtubule-associated protein tau

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains."
Himmler A. , Drechsel D. , Kirschner M.W. , Martin D.W. Jr.
Mol. Cell. Biol.9:1381-1388(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS TAU-A; TAU-B; TAU-G AND TAU-H)
tissue: Brain.
2.

"Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family."
Himmler A.
Mol. Cell. Biol.9:1389-1396(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS TAU-A; TAU-B; TAU-C; TAU-D; TAU-E; TAU-F; TAU-I; TAU-J; TAU-K; TAU-L; TAU-M; TAU-N; TAU-O; TAU-P; TAU-Q; TAU-R; TAU-S AND TAU-T)
tissue: Brain.
3.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2005-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM TAU-F)
strain: Crossbred X Angus.
tissue: Liver.
4.

"The microtubule-associated protein tau is extensively modified with O-linked N-acetylglucosamine."
Arnold C.S. , Johnson G.V.W. , Cole R.N. , Dong D.L.-Y. , Lee M. , Hart G.W.
J. Biol. Chem.271:28741-28744(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION

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