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Index > Protein center > TUBA1A(Gene name) > Human
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  • TUBA1A (Gene name),
  • Tubulin alpha-1A chain (Protein name ),  TBA1A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TUBA1A(TUBA3);
    Protein name:
    Tubulin alpha-1A chain;
    Alternative:
    Tubulin B-alpha-1;Alpha-tubulin 3;Tubulin alpha-3 chain;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Dimer of alpha and beta chains.
    Function:
    Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    451
    Sequence:
    50:
    MRECISIHVG | QAGVQIGNAC | WELYCLEHGI | QPDGQMPSDK | TIGGGDDSFN | 
    100:
    TFFSETGAGK | HVPRAVFVDL | EPTVIDEVRT | GTYRQLFHPE | QLITGKEDAA | 
    150:
    NNYARGHYTI | GKEIIDLVLD | RIRKLADQCT | GLQGFLVFHS | FGGGTGSGFT | 
    200:
    SLLMERLSVD | YGKKSKLEFS | IYPAPQVSTA | VVEPYNSILT | THTTLEHSDC | 
    250:
    AFMVDNEAIY | DICRRNLDIE | RPTYTNLNRL | IGQIVSSITA | SLRFDGALNV | 
    300:
    DLTEFQTNLV | PYPRIHFPLA | TYAPVISAEK | AYHEQLSVAE | ITNACFEPAN | 
    350:
    QMVKCDPRHG | KYMACCLLYR | GDVVPKDVNA | AIATIKTKRT | IQFVDWCPTG | 
    400:
    FKVGINYQPP | TVVPGGDLAK | VQRAVCMLSN | TTAIAEAWAR | LDHKFDLMYA | 
    450:
    KRAFVHWYVG | EGMEEGEFSE | AREDMAALEK | DYEEVGVDSV | EGEGEEEGEE | 
    451:
    Y
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    MIM:
    UniGene:
    KEGG:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tubulin alpha-1A chain
    Cat.:
    E11226h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Tubulin alpha-1A chain
    Cat.:
    E11226r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Tubulin alpha-1A chain
    Cat.:
    E11226p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Tubulin alpha-1A chain
    Cat.:
    E11226m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tubulin alpha-1A chain
    Cat.:
    U11226h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tubulin alpha-1A chain
    Cat.:
    U11226m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tubulin alpha-1A chain
    Cat.:
    U11226r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tubulin alpha-1A chain
    Cat.:
    U11226p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Tubulin alpha-1A chain
    Cat.:
    P11226Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tubulin alpha-1A chain
    Polyclonal Antibody for Human Tubulin alpha-1A chain
    Cat.:
    P11226Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tubulin alpha-1A chain
    Cat.:
    P11226Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tubulin alpha-1A chain
    Monoclonal Antibody for Human Tubulin alpha-1A chain
    Monoclonal Antibody for Human Tubulin alpha-1A chain
    Monoclonal Antibody for Human Tubulin alpha-1A chain
    Protein for Human Tubulin alpha-1A chain
    Protein for Human Tubulin alpha-1A chain
    Protein for Human Tubulin alpha-1A chain
    Protein for Human Tubulin alpha-1A chain

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    Precision
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    Linearity
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    References
    1. 1.
      "Structural features and restricted expression of a human alpha-tubulin gene."
      Hall J.L. , Cowan N.J.
      Nucleic Acids Res.13:207-223(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Tubulins in the primate retina: evidence that xanthophylls may be endogenous ligands for the paclitaxel-binding site."
      Crabtree D.V. , Ojima I. , Geng X. , Adler A.J.
      Bioorg. Med. Chem.9:1967-1976(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Retina.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Cerebellum.
    4. 4.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Muscle.
      tissue: Skin.
    7. 7.
      Lubec G. , Afjehi-Sadat L. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 41-60; 65-79; 85-105; 113-121; 157-163; 216-304; 312-320; 327-336; 340-352; 374-390; 395-401 AND 403-430;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
      tissue: Fetal brain cortex.
    8. 8.
      "Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions."
      Cowan N.J. , Dobner P. , Fuchs E.V. , Cleveland D.W.
      Mol. Cell. Biol.3:1738-1745(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 110-451
      tissue: Fetal brain.
    9. 9.
      "Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A)."
      Poirier K. , Keays D.A. , Francis F. , Saillour Y. , Bahi N. , Manouvrier S. , Fallet-Bianco C. , Pasquier L. , Toutain A. , Tuy F.P. , Bienvenu T. , Joriot S. , Odent S. , Ville D. , Desguerre I. , Goldenberg A. , Moutard M.L. , Fryns J.-P. , more...
      Hum. Mutat.28:1055-1064(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;VARIANTS LIS3 LEU-188; THR-263; CYS-264; PHE-286; HIS-402; CYS-402 AND LEU-419
    10. 10.
      "Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation."
      Rogowski K. , Juge F. , van Dijk J. , Wloga D. , Strub J.-M. , Levilliers N. , Thomas D. , Bre M.-H. , Van Dorsselaer A. , Gaertig J. , Janke C.
      Cell137:1076-1087(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCYLATION
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