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Index > Protein center > TUBA8(Gene name) > Human
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  • TUBA8 (Gene name),
  • Tubulin alpha-8 chain (Protein name ),  TBA8_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    TUBA8(TUBAL2);
    Protein name:
    Tubulin alpha-8 chain;
    Alternative:
    Tubulin alpha chain-like 2;Alpha-tubulin 8;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Dimer of alpha and beta chains.
    Function:
    Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    449
    Sequence:
    50:
    MRECISVHVG | QAGVQIGNAC | WELFCLEHGI | QADGTFDAQA | SKINDDDSFT | 
    100:
    TFFSETGNGK | HVPRAVMIDL | EPTVVDEVRA | GTYRQLFHPE | QLITGKEDAA | 
    150:
    NNYARGHYTV | GKESIDLVLD | RIRKLTDACS | GLQGFLIFHS | FGGGTGSGFT | 
    200:
    SLLMERLSLD | YGKKSKLEFA | IYPAPQVSTA | VVEPYNSILT | THTTLEHSDC | 
    250:
    AFMVDNEAIY | DICRRNLDIE | RPTYTNLNRL | ISQIVSSITA | SLRFDGALNV | 
    300:
    DLTEFQTNLV | PYPRIHFPLV | TYAPIISAEK | AYHEQLSVAE | ITSSCFEPNS | 
    350:
    QMVKCDPRHG | KYMACCMLYR | GDVVPKDVNV | AIAAIKTKRT | IQFVDWCPTG | 
    400:
    FKVGINYQPP | TVVPGGDLAK | VQRAVCMLSN | TTAIAEAWAR | LDHKFDLMYA | 
    449:
    KRAFVHWYVG | EGMEEGEFSE | AREDLAALEK | DYEEVGTDSF | EEENEGEEF
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    UniGene:
    KEGG:
    SMR:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tubulin alpha-8 chain
    Cat.:
    E11228h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Tubulin alpha-8 chain
    Cat.:
    E11228b
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    Packing:
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    ELISA Kit for Human Tubulin alpha-8 chain
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    E11228m
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    96T
    ELISA Kit for Human Tubulin alpha-8 chain
    Cat.:
    E11228r
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    Packing:
    96T
    CLIA Kit for Human Tubulin alpha-8 chain
    Cat.:
    U11228b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Tubulin alpha-8 chain
    Cat.:
    U11228h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tubulin alpha-8 chain
    Cat.:
    U11228m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Tubulin alpha-8 chain
    Cat.:
    U11228r
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Tubulin alpha-8 chain
    Cat.:
    P11228Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tubulin alpha-8 chain
    Cat.:
    P11228Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tubulin alpha-8 chain
    Polyclonal Antibody for Human Tubulin alpha-8 chain
    Cat.:
    P11228Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tubulin alpha-8 chain
    Monoclonal Antibody for Human Tubulin alpha-8 chain
    Monoclonal Antibody for Human Tubulin alpha-8 chain
    Monoclonal Antibody for Human Tubulin alpha-8 chain
    Protein for Human Tubulin alpha-8 chain
    Protein for Human Tubulin alpha-8 chain
    Protein for Human Tubulin alpha-8 chain
    Protein for Human Tubulin alpha-8 chain

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    References
    1. 1.
      "TUBA8: a new tissue-specific isoform of alpha-tubulin that is highly conserved in human and mouse."
      Stanchi F. , Corso V. , Scannapieco P. , Ievolella C. , Negrisolo E. , Tiso N. , Lanfranchi G. , Valle G.
      Biochem. Biophys. Res. Commun.270:1111-1118(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Skeletal muscle.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Caudate nucleus.
      tissue: Skeletal muscle.
    4. 4.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (ISOFORM 1)
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    7. 7.
      "Mutation of the variant alpha-tubulin TUBA8 results in polymicrogyria with optic nerve hypoplasia."
      Abdollahi M.R. , Morrison E. , Sirey T. , Molnar Z. , Hayward B.E. , Carr I.M. , Springell K. , Woods C.G. , Ahmed M. , Hattingh L. , Corry P. , Pilz D.T. , Stoodley N. , Crow Y. , Taylor G.R. , Bonthron D.T. , Sheridan E.
      Am. J. Hum. Genet.85:737-744(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN PMGONH
    8. 8.
      "Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation."
      Rogowski K. , Juge F. , van Dijk J. , Wloga D. , Strub J.-M. , Levilliers N. , Thomas D. , Bre M.-H. , Van Dorsselaer A. , Gaertig J. , Janke C.
      Cell137:1076-1087(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCYLATION
    9. 9.
      "Tuba8 is expressed at low levels in the developing mouse and human brain."
      Braun A. , Breuss M. , Salzer M.C. , Flint J. , Cowan N.J. , Keays D.A.
      Am. J. Hum. Genet.86:819-822(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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