Gene name:
Tbl1xr1 (Ira1;Tblr1) ;
Protein name:
F-box-like/WD repeat-containing protein TBL1XR1 ;
Alternative:
TBL1-related protein 1 ;Nuclear receptor corepressor/HDAC3 complex subunit TBLR1 ;Transducin beta-like 1X-related protein 1 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1XR1, CORO2A and GPS2. Probable component of some E3 ubiquitin ligase complex. Interacts with histones H2B and H4.
Function:
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MSISSDEVNF | LVYRYLQESG | FSHSAFTFGI | ESHISQSNIN | GALVPPAALI |
100:
SIIQKGLQYV | EAEVSINEDG | TLFDGRPIES | LSLIDAVMPD | VVQTRQQAYR |
150:
DKLAQQHAAA | AAAAAAATNQ | QGSAKNGENT | ANGEENGAHT | IANNHTDMME |
200:
VDGDVEIPSN | KAVVLRGHES | EVFICAWNPV | SDLLASGSGD | STARIWNLSE |
250:
NSTSGPTQLV | LRHCIREGGQ | DVPSNKDVTS | LDWNSEGTLL | ATGSYDGFAR |
300:
IWTKDGNLAS | TLGQHKGPIF | ALKWNKKGNF | ILSAGVDKTT | IIWDAHTGEA |
350:
KQQFPFHSAP | ALDVDWQSNN | TFASCSTDMC | IHVCKLGQDR | PIKTFQGHTN |
400:
EVNAIKWDPT | GNLLASCSDD | MTLKIWSMKQ | DNCVHDLQAH | NKEIYTIKWS |
450:
PTGPGTNNPN | ANLMLASASF | DSTVRLWDVD | RGICIHTLTK | HQEPVYSVAF |
500:
SPDGRYLASG | SFDKCVHIWN | TQTGALVHSY | RGTGGIFEVC | WNAAGDKVGA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse F-box-like/WD repeat-containing protein TBL1XR1
ELISA Kit for Mouse F-box-like/WD repeat-containing protein TBL1XR1
CLIA Kit for Mouse F-box-like/WD repeat-containing protein TBL1XR1
CLIA Kit for Mouse F-box-like/WD repeat-containing protein TBL1XR1
Polyclonal Antibody for Mouse F-box-like/WD repeat-containing protein TBL1XR1
Polyclonal Antibody for Mouse F-box-like/WD repeat-containing protein TBL1XR1
Monoclonal Antibody for Mouse F-box-like/WD repeat-containing protein TBL1XR1
Monoclonal Antibody for Mouse F-box-like/WD repeat-containing protein TBL1XR1
Protein for Mouse F-box-like/WD repeat-containing protein TBL1XR1
Protein for Mouse F-box-like/WD repeat-containing protein TBL1XR1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
BALB/c .
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[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Cerebellum .
tissue :
Egg .
tissue :
Testis .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 314-514
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Mammary tumor .
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-102;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .