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Index > Protein center > Tet3(Gene name) > Mouse
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  • Tet3 (Gene name),
  • Methylcytosine dioxygenase TET3 (Protein name ),  TET3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Tet3;
    Protein name:
    Methylcytosine dioxygenase TET3;
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC).
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    1668
    Sequence:
    50:
    MDSGPVYHGD | SRQLSTSGAP | VNGAREPAGP | GLLGAAGPWR | VDQKPDWEAA | 
    100:
    SGPTHAARLE | DAHDLVAFSA | VAEAVSSYGA | LSTRLYETFN | REMSREAGSN | 
    150:
    GRGPRPESCS | EGSEDLDTLQ | TALALARHGM | KPPNCTCDGP | ECPDFLEWLE | 
    200:
    GKIKSMAMEG | GQGRPRLPGA | LPPSEAGLPA | PSTRPPLLSS | EVPQVPPLEG | 
    250:
    LPLSQSALSI | AKEKNISLQT | AIAIEALTQL | SSALPQPSHS | TSQASCPLPE | 
    300:
    ALSPSAPFRS | PQSYLRAPSW | PVVPPEEHPS | FAPDSPAFPP | ATPRPEFSEA | 
    350:
    WGTDTPPATP | RNSWPVPRPS | PDPMAELEQL | LGSASDYIQS | VFKRPEALPT | 
    400:
    KPKVKVEAPS | SSPAPVPSPI | SQREAPLLSS | EPDTHQKAQT | ALQQHLHHKR | 
    450:
    NLFLEQAQDA | SFPTSTEPQA | PGWWAPPGSP | APRPPDKPPK | EKKKKPPTPA | 
    500:
    GGPVGAEKTT | PGIKTSVRKP | IQIKKSRSRD | MQPLFLPVRQ | IVLEGLKPQA | 
    550:
    SEGQAPLPAQ | LSVPPPASQG | AASQSCATPL | TPEPSLALFA | PSPSGDSLLP | 
    600:
    PTQEMRSPSP | MVALQSGSTG | GPLPPADDKL | EELIRQFEAE | FGDSFGLPGP | 
    650:
    PSVPIQEPEN | QSTCLPAPES | PFATRSPKKI | KIESSGAVTV | LSTTCFHSEE | 
    700:
    GGQEATPTKA | ENPLTPTLSG | FLESPLKYLD | TPTKSLLDTP | AKKAQSEFPT | 
    750:
    CDCVEQIVEK | DEGPYYTHLG | SGPTVASIRE | LMEDRYGEKG | KAIRIEKVIY | 
    800:
    TGKEGKSSRG | CPIAKWVIRR | HTLEEKLLCL | VRHRAGHHCQ | NAVIVILILA | 
    850:
    WEGIPRSLGD | TLYQELTDTL | RKYGNPTSRR | CGLNDDRTCA | CQGKDPNTCG | 
    900:
    ASFSFGCSWS | MYFNGCKYAR | SKTPRKFRLT | GDNPKEEEVL | RNSFQDLATE | 
    950:
    VAPLYKRLAP | QAYQNQVTNE | DVAIDCRLGL | KEGRPFSGVT | ACMDFCAHAH | 
    1000:
    KDQHNLYNGC | TVVCTLTKED | NRCVGQIPED | EQLHVLPLYK | MASTDEFGSE | 
    1050:
    ENQNAKVSSG | AIQVLTAFPR | EVRRLPEPAK | SCRQRQLEAR | KAAAEKKKLQ | 
    1100:
    KEKLSTPEKI | KQEALELAGV | TTDPGLSLKG | GLSQQSLKPS | LKVEPQNHFS | 
    1150:
    SFKYSGNAVV | ESYSVLGSCR | PSDPYSMSSV | YSYHSRYAQP | GLASVNGFHS | 
    1200:
    KYTLPSFGYY | GFPSSNPVFP | SQFLGPSAWG | HGGSGGSFEK | KPDLHALHNS | 
    1250:
    LNPAYGGAEF | AELPGQAVAT | DNHHPIPHHQ | QPAYPGPKEY | LLPKVPQLHP | 
    1300:
    ASRDPSPFAQ | SSSCYNRSIK | QEPIDPLTQA | ESIPRDSAKM | SRTPLPEASQ | 
    1350:
    NGGPSHLWGQ | YSGGPSMSPK | RTNSVGGNWG | VFPPGESPTI | VPDKLNSFGA | 
    1400:
    SCLTPSHFPE | SQWGLFTGEG | QQSAPHAGAR | LRGKPWSPCK | FGNGTSALTG | 
    1450:
    PSLTEKPWGM | GTGDFNPALK | GGPGFQDKLW | NPVKVEEGRI | PTPGANPLDK | 
    1500:
    AWQAFGMPLS | SNEKLFGALK | SEEKLWDPFS | LEEGTAEEPP | SKGVVKEEKS | 
    1550:
    GPTVEEDEEE | LWSDSEHNFL | DENIGGVAVA | PAHCSILIEC | ARRELHATTP | 
    1600:
    LKKPNRCHPT | RISLVFYQHK | NLNQPNHGLA | LWEAKMKQLA | ERARQRQEEA | 
    1650:
    ARLGLGQQEA | KLYGKKRKWG | GAMVAEPQHK | EKKGAIPTRQ | ALAMPTDSAV | 
    1668:
    TVSSYAYTKV | TGPYSRWI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Methylcytosine dioxygenase TET3
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    ELISA Kit for Mouse Methylcytosine dioxygenase TET3
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    CLIA Kit for Mouse Methylcytosine dioxygenase TET3
    Cat.:
    U7456h
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    Packing:
    96T
    CLIA Kit for Mouse Methylcytosine dioxygenase TET3
    Cat.:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Methylcytosine dioxygenase TET3
    Cat.:
    P7456Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Methylcytosine dioxygenase TET3
    Cat.:
    P7456Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Methylcytosine dioxygenase TET3
    Monoclonal Antibody for Mouse Methylcytosine dioxygenase TET3
    Protein for Mouse Methylcytosine dioxygenase TET3
    Protein for Mouse Methylcytosine dioxygenase TET3

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Adipose tissue.
      tissue: Retina.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 757-1553 (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Egg.
    4. 4.
      "Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification."
      Ito S. , D'Alessio A.C. , Taranova O.V. , Hong K. , Sowers L.C. , Zhang Y.
      Nature466:1129-1133(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;TISSUE SPECIFICITY;MUTAGENESIS OF HIS-950 AND ASP-952
    5. 5.
      "The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes."
      Gu T.P. , Guo F. , Yang H. , Wu H.P. , Xu G.F. , Liu W. , Xie Z.G. , Shi L. , He X. , Jin S.G. , Iqbal K. , Shi Y.G. , Deng Z. , Szabo P.E. , Pfeifer G.P. , Li J. , Xu G.L.
      Nature477:606-610(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DISRUPTION PHENOTYPE
    6. 6.
      "5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming."
      Wossidlo M. , Nakamura T. , Lepikhov K. , Marques C.J. , Zakhartchenko V. , Boiani M. , Arand J. , Nakano T. , Reik W. , Walter J.
      Nat. Commun.2:241-241(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    7. 7.
      "Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine."
      Iqbal K. , Jin S.G. , Pfeifer G.P. , Szabo P.E.
      Proc. Natl. Acad. Sci. U.S.A.108:3642-3647(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    8. 8.
      "Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine."
      Ito S. , Shen L. , Dai Q. , Wu S.C. , Collins L.B. , Swenberg J.A. , He C. , Zhang Y.
      Science333:1300-1303(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;MUTAGENESIS OF HIS-950 AND ASP-952
    9. 9.
      "PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos."
      Nakamura T. , Liu Y.J. , Nakashima H. , Umehara H. , Inoue K. , Matoba S. , Tachibana M. , Ogura A. , Shinkai Y. , Nakano T.
      Nature486:415-419(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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