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Index > Protein center > ZFP36L2(Gene name) > Human
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  • ZFP36L2 (Gene name),
  • Zinc finger protein 36, C3H1 type-like 2 (Protein name ),  TISD_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ZFP36L2(BRF2;ERF2;RNF162C;TIS11D);
    Protein name:
    Zinc finger protein 36, C3H1 type-like 2(ZFP36-like 2);
    Alternative:
    EGF-response factor 2(ERF-2);Butyrate response factor 2;Protein TIS11D;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    494
    Sequence:
    50:
    MSTTLLSAFY | DVDFLCKTEK | SLANLNLNNM | LDKKAVGTPV | AAAPSSGFAP | 
    100:
    GFLRRHSASN | LHALAHPAPS | PGSCSPKFPG | AANGSSCGSA | AAGGPTSYGT | 
    150:
    LKEPSGGGGT | ALLNKENKFR | DRSFSENGDR | SQHLLHLQQQ | QKGGGGSQIN | 
    200:
    STRYKTELCR | PFEESGTCKY | GEKCQFAHGF | HELRSLTRHP | KYKTELCRTF | 
    250:
    HTIGFCPYGP | RCHFIHNADE | RRPAPSGGAS | GDLRAFGTRD | ALHLGFPREP | 
    300:
    RPKLHHSLSF | SGFPSGHHQP | PGGLESPLLL | DSPTSRTPPP | PSCSSASSCS | 
    350:
    SSASSCSSAS | AASTPSGAPT | CCASAAAAAA | AALLYGTGGA | EDLLAPGAPC | 
    400:
    AACSSASCAN | NAFAFGPELS | SLITPLAIQT | HNFAAVAAAA | YYRSQQQQQQ | 
    450:
    QGLAPPAQPP | APPSATLPAG | AAAPPSPPFS | FQLPRRLSDS | PVFDAPPSPP | 
    494:
    DSLSDRDSYL | SGSLSSGSLS | GSESPSLDPG | RRLPIFSRLS | ISDD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    MIM:
    KEGG:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human ZFP36-like 2
    Cat.:
    E5956h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human ZFP36-like 2
    Cat.:
    E5956m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human ZFP36-like 2
    Cat.:
    U5956m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ZFP36-like 2
    Cat.:
    U5956h
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human ZFP36-like 2
    Cat.:
    P5956Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ZFP36-like 2
    Cat.:
    P5956Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human ZFP36-like 2
    Monoclonal Antibody for Human ZFP36-like 2
    Protein for Human ZFP36-like 2
    Protein for Human ZFP36-like 2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification of a member of the TIS11 early response gene family at the insertion point of a DNA fragment containing a gene for the T-cell receptor beta chain in an acute T-cell leukemia."
      Ino T. , Yasui H. , Hirano M. , Kurosawa Y.
      Oncogene11:2705-2710(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "ERF-2, the human homologue of the murine Tis11d early response gene."
      Nie X.F. , Maclean K.N. , Kumar V. , McKay I.A. , Bustin S.A.
      Gene152:285-286(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Pancreas.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-57;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      "A computational study of RNA binding and specificity in the tandem zinc finger domain of TIS11d."
      Morgan B.R. , Massi F.
      Protein Sci.19:1222-1234(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RNA-BINDING;MUTAGENESIS OF GLU-157 AND GLU-195
    8. 8.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "Mutation in the RNA binding protein TIS11D/ZFP36L2 is associated with the pathogenesis of acute leukemia."
      Iwanaga E. , Nanri T. , Mitsuya H. , Asou N.
      Int. J. Oncol.38:25-31(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE INVOLVEMENT IN LEUKEMIAS
    10. 10.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-125;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d."
      Hudson B.P. , Martinez-Yamout M.A. , Dyson H.J. , Wright P.E.
      Nat. Struct. Mol. Biol.11:257-264(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 151-220 IN COMPLEX WITH RNA;FUNCTION;RNA-BINDING
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