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Index > Protein center > TLR2(Gene name) > Bovine
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  • TLR2 (Gene name),
  • Toll-like receptor 2 (Protein name ),  TLR2_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TLR2;
    Protein name:
    Toll-like receptor 2;
    Alternative:

    CD:
    CD282;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Interacts with LY96, TLR1 and TLR6 (via extracellular domain). Binds MYD88 (via TIR domain). Interacts with TICAM1. Ligand binding induces the formation of a heterodimer with TLR1 (By similarity). Interacts with CNPY3.
    Function:
    Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    784
    Sequence:
    50:
    MPRALWTAWV | WAVIILSTEG | ASDQASSLSC | DPTGVCDGHS | RSLNSIPSGL | 
    100:
    TAGVKSLDLS | NNDITYVGNR | DLQRCVNLKT | LRLGANEIHT | VEEDSFFHLR | 
    150:
    NLEYLDLSYN | RLSNLSSSWF | RSLYVLKFLN | LLGNLYKTLG | ETSLFSHLPN | 
    200:
    LRTLKVGNSN | SFTEIHEKDF | TGLTFLEELE | ISAQNLQIYV | PKSLKSIQNI | 
    250:
    SHLILHLKQP | ILLVDILVDI | VSSLDCFELR | DTNLHTFHFS | EASISEMSTS | 
    300:
    VKKLIFRNVQ | FTDESFVEVV | KLFNYVSGIL | EVEFDDCTHD | GIGDFRALSL | 
    350:
    DRIRHLGNVE | TLTIRKLHIP | QFFLFHDLSS | IYPLTGRVKR | VTIENSKVFL | 
    400:
    VPCLLSQHLK | SLEYLDLSEN | LMSEETLKNS | ACKDAWPFLQ | TLVLRQNRLK | 
    450:
    SLEKTGELLL | TLENLNNLDI | SKNNFLSMPE | TCQWPGKMKQ | LNLSSTRIHS | 
    500:
    LTQCLPQTLE | ILDVSNNNLD | SFSLILPQLK | ELYISRNKLK | TLPDASFLPV | 
    550:
    LSVMRISRNI | INTFSKEQLD | SFQQLKTLEA | GGNNFICSCD | FLSFTQGQQA | 
    600:
    LGRVLVDWPD | DYRCDSPSHV | RGQRVQDARL | SLSECHRAAV | VSAACCALFL | 
    650:
    LLLLTGVLCH | RFHGLWYMKM | MWAWLQAKRK | PRKAPRRDIC | YDAFVSYSER | 
    700:
    DSYWVENLMV | QELEHFNPPF | KLCLHKRDFI | PGKWIIDNII | DSIEKSHKTI | 
    750:
    FVLSENFVKS | EWCKYELDFS | HFRLFDENND | AAILILLEPI | DKKAIPQRFC | 
    784:
    KLRKIMNTKT | YLEWPVDETQ | QEGFWLNLRA | AIRS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    Pfam:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Toll-like receptor 2
    Cat.:
    E0663h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Bovine Toll-like receptor 2
    Cat.:
    E0663m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Toll-like receptor 2
    Cat.:
    E0663d
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine Toll-like receptor 2
    Cat.:
    E0663b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Toll-like receptor 2
    Cat.:
    U0663b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Toll-like receptor 2
    Cat.:
    U0663d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Toll-like receptor 2
    Cat.:
    U0663m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Toll-like receptor 2
    Cat.:
    U0663h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Toll-like receptor 2
    Polyclonal Antibody for Bovine Toll-like receptor 2
    Cat.:
    P0663Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Toll-like receptor 2
    Cat.:
    P0663Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Toll-like receptor 2
    Monoclonal Antibody for Bovine Toll-like receptor 2
    Monoclonal Antibody for Bovine Toll-like receptor 2
    Monoclonal Antibody for Bovine Toll-like receptor 2
    Monoclonal Antibody for Bovine Toll-like receptor 2
    Protein for Bovine Toll-like receptor 2
    Protein for Bovine Toll-like receptor 2
    Protein for Bovine Toll-like receptor 2
    Protein for Bovine Toll-like receptor 2

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    Precision
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    Linearity
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    Citations
    [1].
    References
    1. 1.
      "Role of bovine TLR2, TLR4 and CD14 in the recognition of bacterial constituents."
      Guionaud C.T. , Dubey C. , Zumkehr J.R. , Sonstegard T.S. , Jungi T.W.
      Submitted (2001-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Role of bovine TLRs in antigen presentation."
      Werling D. , McGuire K. , Glass E.
      Submitted (2004-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Analysis of sequence variability and protein domain architectures for bovine peptidoglycan recognition protein 1 and Toll-like receptors 2 and 6."
      Seabury C.M. , Womack J.E.
      Genomics92:235-245(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLU-290 AND LYS-783
      strain: Isolate 44.
      strain: Isolate 74.
      strain: Isolate 80.
      strain: Isolate JEW38.
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