Tlr6 ELISA Kit for Mouse(Mus musculus) | EIAab.comTlr6 ELISA Kit for Mouse(Mus musculus)

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Tlr6 (Gene name),

Toll-like receptor 6 (Protein name ), TLR6_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Tlr6;

Protein name:

Toll-like receptor 6;

Alternative:

CD:

CD286;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Binds TLR2 via their respective extracellular domains. Binds MYD88 via their respective TIR domains.

Function:

Participates in the innate immune response to Gram-positive bacteria and fungi. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Cooperates with TLR2 for the cellular activation.

Subcellular Location:

Cell membrane Single-pass type I membrane protein Cytoplasmic vesicle phagosome membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

795

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

795:

LRALMAQRTY | LEWPTEKGKR | GLFWANLRAS | FIMKLALVNE | DDVKT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.42146

String:

Q9EPW9

KEGG:

mmu:21899

SMR:

Q9EPW9

Pfam:

PF00560

Uniprot:

Q9EPW9

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ELISA Kit for Mouse Toll-like receptor 6

Cat.:

E0683m

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96T

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ELISA Kit for Mouse Toll-like receptor 6

Cat.:

E0683h

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96T

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ELISA Kit for Mouse Toll-like receptor 6

Cat.:

E0683b

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Packing:

96T

CLIA Kit for Mouse Toll-like receptor 6

Cat.:

U0683m

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Packing:

96T

CLIA Kit for Mouse Toll-like receptor 6

Cat.:

U0683h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Toll-like receptor 6

Cat.:

U0683b

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96T

Polyclonal Antibody for Mouse Toll-like receptor 6

Cat.:

P0683Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Toll-like receptor 6

Cat.:

P0683Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Toll-like receptor 6

Protein for Mouse Toll-like receptor 6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"TLR6: a novel member of an expanding Toll-like receptor family."
Takeuchi O. , Kawai T. , Sanjo H. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Takeda K. , Akira S.
Gene231:59-65(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Embryo.
2.

"The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors."
Ozinsky A. , Underhill D.M. , Fontenot J.D. , Hajjar A.M. , Smith K.D. , Wilson C.B. , Schroeder L. , Aderem A.
Proc. Natl. Acad. Sci. U.S.A.97:13766-13771(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];MUTAGENESIS OF PRO-680
strain: BALB/c.
tissue: Macrophage.
3.

"CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer."
Stewart C.R. , Stuart L.M. , Wilkinson K. , van Gils J.M. , Deng J. , Halle A. , Rayner K.J. , Boyer L. , Zhong R. , Frazier W.A. , Lacy-Hulbert A. , El Khoury J. , Golenbock D.T. , Moore K.J.
Nat. Immunol.11:155-161(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
4.

"Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer."
Kang J.Y. , Nan X. , Jin M.S. , Youn S.J. , Ryu Y.H. , Mah S. , Han S.H. , Lee H. , Paik S.G. , Lee J.O.
Immunity31:873-884(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) OF 1-483 IN COMPLEX WITH TLR2 AND LIPOPEPTIDE;DISULFIDE BONDS;GLYCOSYLATION AT ASN-144; ASN-195; ASN-214; ASN-253; ASN-359; ASN-401 AND ASN-434;FUNCTION;LRR REPEATS;SUBUNIT

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