Gene name:
Faslg (Apt1Lg1;Cd95l;Fasl;Tnfsf6) ;
Protein name:
Tumor necrosis factor ligand superfamily member 6 ;
Alternative:
Fas antigen ligand (Fas ligand) ;CD95 ligand (CD95-L) ;
CD:
CD178 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Homotrimer (Probable). Interacts with ARHGAP9, BAIAP2L1, BTK, CACNB3, CACNB4, CRK, DLG2, DNMBP, DOCK4, EPS8L3, FGR, FYB, FYN, HCK, ITK, ITSN2, KALRN, LYN, MACC1, MIA, MPP4, MYO15A, NCF1, NCK1, NCK2, NCKIPSD, OSTF1, PIK3R1, PSTPIP1, RIMBP3C, SAMSN1, SH3GL3, SH3PXD2B, SH3PXD2A, SH3RF2, SKAP2, SNX33, SNX9, SORBS3, SPTA1, SRC, SRGAP1, SRGAP2, SRGAP3, TEC, TJP3 and YES1.
Function:
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
Subcellular Location:
Tumor necrosis factor ligand superfamily member 6, soluble form
Secreted
May be released into the extracellular fluid, probably by cleavage form the cell surface.
Protein Attributes:
50:
MQQPVNYPCP | QIYWVDSSAT | SPWAPPGSVF | SCPSSGPRGP | GQRRPPPPPP |
100:
PPSPLPPPSQ | PPPLPPLSPL | KKKDNIELWL | PVIFFMVLVA | LVGMGLGMYQ |
150:
LFHLQKELAE | LREFTNHSLR | VSSFEKQIAN | PSTPSETKKP | RSVAHLTGNP |
200:
RSRSIPLEWE | DTYGTALISG | VKYKKGGLVI | NEAGLYFVYS | KVYFRGQSCN |
250:
SQPLSHKVYM | RNFKYPGDLV | LMEEKKLNYC | TTGQIWAHSS | YLGAVFNLTV |
278:
ADHLYVNISQ | LSLINFEESK | TFFGLYKL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
Pig
ELISA Kit for Rat Tumor necrosis factor ligand superfamily member 6
ELISA Kit for Rat Tumor necrosis factor ligand superfamily member 6
ELISA Kit for Rat Tumor necrosis factor ligand superfamily member 6
ELISA Kit for Rat Tumor necrosis factor ligand superfamily member 6
CLIA Kit for Rat Tumor necrosis factor ligand superfamily member 6
CLIA Kit for Rat Tumor necrosis factor ligand superfamily member 6
CLIA Kit for Rat Tumor necrosis factor ligand superfamily member 6
CLIA Kit for Rat Tumor necrosis factor ligand superfamily member 6
Polyclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 6
Polyclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 6
Polyclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 6
Polyclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 6
Monoclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 6
Monoclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 6
Monoclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 6
Monoclonal Antibody for Rat Tumor necrosis factor ligand superfamily member 6
Protein for Rat Tumor necrosis factor ligand superfamily member 6
Protein for Rat Tumor necrosis factor ligand superfamily member 6
Protein for Rat Tumor necrosis factor ligand superfamily member 6
Protein for Rat Tumor necrosis factor ligand superfamily member 6
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]