Protein name:
Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2;TNF alpha-induced protein 8-like protein 2;TNFAIP8-like protein 2) ;
Alternative:
Inflammation factor protein 20 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
May interact with CASP8; however, such result is unclear since PubMed:19079267 could not reproduce the interaction with CASP8.
Function:
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis.
Subcellular Location:
N/A
Protein Attributes:
50:
MESFSSKSLA | LQAEKKLLSK | MAGRSVAHLF | IDETSSEVLD | ELYRVSKEYT |
100:
HSRPQAQRVI | KDLIKVAIKV | AVLHRNGSFG | PSELALATRF | RQKLRQGAMT |
150:
ALSFGEVDFT | FEAAVLAGLL | TECRDVLLEL | VEHHLTPKSH | GRIRHVFDHF |
184:
SDPGLLTALY | GPDFTQHLGK | ICDGLRKLLD | EGKL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rabbit
Mouse
Human
Rat
Bovine
ELISA Kit for Human TIPE2
ELISA Kit for Human TIPE2
ELISA Kit for Human TIPE2
ELISA Kit for Human TIPE2
ELISA Kit for Human TIPE2
Polyclonal Antibody for Human TIPE2
Polyclonal Antibody for Human TIPE2
Polyclonal Antibody for Human TIPE2
Polyclonal Antibody for Human TIPE2
Polyclonal Antibody for Human TIPE2
Monoclonal Antibody for Human TIPE2
Monoclonal Antibody for Human TIPE2
Monoclonal Antibody for Human TIPE2
Monoclonal Antibody for Human TIPE2
Monoclonal Antibody for Human TIPE2
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Small intestine .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Pancreas .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS);LACK OF INTERACTION WITH CASP8