Protein name:
Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2;TNF alpha-induced protein 8-like protein 2;TNFAIP8-like protein 2) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
May interact with CASP8; however, such result is unclear.
Function:
Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis.
Subcellular Location:
N/A
Protein Attributes:
50:
MESFSSKSLA | LQAEKKLLSK | MAGRSVAHLF | IDETSSEVLD | ELYRVSKEYT |
100:
HSRPKAQRVI | KDLIKVAVKV | AVLHRSGCFG | PGELALATRF | RQKLRQGAMT |
150:
ALSFGEVDFT | FEAAVLAGLL | VECRDILLEL | VEHHLTPKSH | DRIRHVFDHY |
184:
SDPDLLAALY | GPDFTQHLGK | ICDGLRKLLD | EGKL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rabbit
Mouse
Human
Rat
Bovine
ELISA Kit for Mouse TIPE2
ELISA Kit for Mouse TIPE2
ELISA Kit for Mouse TIPE2
ELISA Kit for Mouse TIPE2
ELISA Kit for Mouse TIPE2
Polyclonal Antibody for Mouse TIPE2
Polyclonal Antibody for Mouse TIPE2
Polyclonal Antibody for Mouse TIPE2
Polyclonal Antibody for Mouse TIPE2
Polyclonal Antibody for Mouse TIPE2
Monoclonal Antibody for Mouse TIPE2
Monoclonal Antibody for Mouse TIPE2
Monoclonal Antibody for Mouse TIPE2
Monoclonal Antibody for Mouse TIPE2
Monoclonal Antibody for Mouse TIPE2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis."
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Cell133:415-426(2008)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH CASP8;INDUCTION;TISSUE SPECIFICITY;DISRUPTION PHENOTYPE
strain :
C57BL/6J .
tissue :
Spinal cord .
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"The transcriptional landscape of the mammalian genome."
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Pancreas .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Mammary tumor .
tissue :
Thymus .