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Index > Protein center > Tradd(Gene name) > Mouse
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  • Tradd (Gene name),
  • Tumor necrosis factor receptor type 1-associated DEATH domain protein (Protein name ),  TRADD_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Tradd;
    Protein name:
    Tumor necrosis factor receptor type 1-associated DEATH domain protein(TNFR1-associated DEATH domain protein);
    Alternative:
    TNFRSF1A-associated via death domain;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer with TNFRSF1A/TNFR1. Interacts with DAB2IP, FADD, HIPK2, KRT18, RIPK1, SQSTM1, TRAF1, TRAF2 and TRPC4AP (By similarity). Interacts with KRT14, KRT16 and KRT17.
    Function:
    Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    310
    Sequence:
    50:
    MAAGQNGHEE | WVGSAYLFLE | SAVDKVILSE | AYTDPKKKVA | IYKALQTALS | 
    100:
    ESGDSSDVLQ | ILKIHCSDPQ | LIVQLRFCGR | VLCGRFLQAY | REGALRTALQ | 
    150:
    RCMAPALAQE | ALRLQLELRA | GAEQLDSWLT | DEERCLNYIL | AQKPDRLRDE | 
    200:
    ELAELEDELC | KLTCDCTGQG | GAIQVASAGS | KFPVSSPTEE | KPLPAACQTF | 
    250:
    LFHGQLVVNR | PLTLQDQQTF | ARSVGLKWRR | VGRSLQRNCR | ALRDPALDSL | 
    300:
    AYEYERDGLY | EQAFQLLRRF | MQAEGRRATL | QRLVEALEEN | ELTSLAEDLL | 
    310:
    GQAEPDGGLA | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    KEGG:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse TNFR1-associated DEATH domain protein
    ELISA Kit for Mouse TNFR1-associated DEATH domain protein
    ELISA Kit for Mouse TNFR1-associated DEATH domain protein
    CLIA Kit for Mouse TNFR1-associated DEATH domain protein
    CLIA Kit for Mouse TNFR1-associated DEATH domain protein
    CLIA Kit for Mouse TNFR1-associated DEATH domain protein
    Polyclonal Antibody for Mouse TNFR1-associated DEATH domain protein
    Polyclonal Antibody for Mouse TNFR1-associated DEATH domain protein
    Polyclonal Antibody for Mouse TNFR1-associated DEATH domain protein
    Monoclonal Antibody for Mouse TNFR1-associated DEATH domain protein
    Monoclonal Antibody for Mouse TNFR1-associated DEATH domain protein
    Monoclonal Antibody for Mouse TNFR1-associated DEATH domain protein
    Protein for Mouse TNFR1-associated DEATH domain protein
    Protein for Mouse TNFR1-associated DEATH domain protein
    Protein for Mouse TNFR1-associated DEATH domain protein

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: NOD.
      tissue: Spleen.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    3. 3.
      "Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion."
      Tong X. , Coulombe P.A.
      Genes Dev.20:1353-1364(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KRT14; KRT16 AND KRT17;SUBCELLULAR LOCATION
    4. 4.
      "TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation."
      Chio I.I. , Sasaki M. , Ghazarian D. , Moreno J. , Done S. , Ueda T. , Inoue S. , Chang Y.L. , Chen N.J. , Mak T.W.
      Nat. Cell Biol.14:625-633(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;DISRUPTION PHENOTYPE;INTERACTION WITH TRIP12;MUTAGENESIS OF 297-GLU--LEU-299
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