TRIM13 ELISA Kit for Bovine(Bos taurus) | EIAab.comTRIM13 ELISA Kit for Bovine(Bos taurus)

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TRIM13 (Gene name),

E3 ubiquitin-protein ligase TRIM13 (Protein name ), TRI13_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TRIM13(RFP2);

Protein name:

E3 ubiquitin-protein ligase TRIM13;

Alternative:

Ret finger protein 2;Putative tumor suppressor RFP2;Tripartite motif-containing protein 13;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Interacts (via C-terminal domain) with VCP. Interacts with AKT1; the interaction ubiquitinates AKT1 and leads to its proteasomal degradation. Interacts with MDM2; the interaction ubiquitinates AKT1 and leads to its proteasomal degradation. Interacts with p62/SQSTM1.

Function:

E3 ubiquitin ligase involved in the retrotranslocation and turnover of membrane and secretory proteins from the ER through a set of processes named ER-associated degradation (ERAD). This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins. Enhances ionizing radiation-induced p53/TP53 stability and apoptosis via ubiquitinating MDM2 and AKT1 and decreasing AKT1 kinase activity through MDM2 and AKT1 proteasomal degradation. Regulates ER stress-induced autophagy, and may act as a tumor suppressor.

Subcellular Location:

Endoplasmic reticulum membrane Single-pass membrane protein Concentrates and colocalizes with p62/SQSTM1 and ZFYVE1 at the perinuclear endoplasmic reticulum.

Protein Attributes:

Sequence length:

407

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

407:

VCKYKLL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9913.ENSBTAP00000010745

Pfam:

PF00643

KEGG:

bta:535190

UniGene:

Bt.5644

Uniprot:

Q32L60

FOR

ELISA Kit for Bovine E3 ubiquitin-protein ligase TRIM13

CLIA Kit for Bovine E3 ubiquitin-protein ligase TRIM13

Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM13

Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM13

Protein for Bovine E3 ubiquitin-protein ligase TRIM13

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A whole-genome assembly of the domestic cow, Bos taurus."
Zimin A.V. , Delcher A.L. , Florea L. , Kelley D.R. , Schatz M.C. , Puiu D. , Hanrahan F. , Pertea G. , Van Tassell C.P. , Sonstegard T.S. , Marcais G. , Roberts M. , Subramanian P. , Yorke J.A. , Salzberg S.L.
Genome Biol.10:R42.01-R42.10(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: Hereford.
2.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2005-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]

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