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Index > Protein center > Trim32(Gene name) > Mouse
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  • Trim32 (Gene name),
  • E3 ubiquitin-protein ligase TRIM32 (Protein name ),  TRI32_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Trim32;
    Protein name:
    E3 ubiquitin-protein ligase TRIM32;
    Alternative:
    Tripartite motif-containing protein 32;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with DTNBP1 (By similarity). It self-associates (By similarity). Interacts with PIAS4/PIASY upon treatement with UVB and TNF-alpha.
    Function:
    Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) (By similarity). Ubiquitinates PIAS4/PIASY and promotes its degradation in keratinocytes treated with UVB and TNF-alpha.
    Subcellular Location:
    Cytoplasm Localized in cytoplasmic bodies, usually concentrated around the nucleus.
    Protein Attributes:
    Sequence length:
    655
    Sequence:
    50:
    MAAAAAASHL | NLDALREVLE | CPICMESFTE | EQLRPKLLHC | GHTICRQCLE | 
    100:
    KLLASSINGV | RCPFCSKITR | ITSLTQLTDN | LTVLKIIDTA | GLSEAVGLLM | 
    150:
    CRGCGRRLPR | QFCRSCGVVL | CEPCREADHQ | PPGHCTLPVK | EAAEERRRDF | 
    200:
    GEKLTRLREL | TGELQRRKAA | LEGVSRDLQA | RYKAVLQEYG | HEERRIQEEL | 
    250:
    ARSRKFFTGS | LAEVEKSNSQ | VVEEQSYLLN | IAEVQAVSRC | DYFLAKIKQA | 
    300:
    DVALLEETAD | EEEPELTASL | PRELTLQDVE | LLKVGHVGPL | QIGQAVKKPR | 
    350:
    TVNMEDSWAG | EEGAASSASA | SVTFREMDMS | PEEVAPSPRA | SPAKQRSSEA | 
    400:
    ASGIQQCLFL | KKMGAKGSTP | GMFNLPVSLY | VTSQSEVLVA | DRGNYRIQVF | 
    450:
    NRKGFLKEIR | RSPSGIDSFV | LSFLGADLPN | LTPLSVAMNC | HGLIGVTDSY | 
    500:
    DNSLKVYTMD | GHCVACHRSQ | LSKPWGITAL | PSGQFVVTDV | EGGKLWCFTV | 
    550:
    DRGAGVVKYS | CLCSAVRPKF | VTCDAEGTVY | FTQGLGLNVE | NRQNEHHLEG | 
    600:
    GFSIGSVGPD | GQLGRQISHF | FSENEDFRCI | AGMCVDARGD | LIVADSSRKE | 
    650:
    ILHFPKGGGY | SVLIREGLTC | PVGIALTPKG | QLLVLDCWDH | CVKIYSYHLR | 
    655:
    RYSTP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse E3 ubiquitin-protein ligase TRIM32
    ELISA Kit for Mouse E3 ubiquitin-protein ligase TRIM32
    CLIA Kit for Mouse E3 ubiquitin-protein ligase TRIM32
    CLIA Kit for Mouse E3 ubiquitin-protein ligase TRIM32
    Polyclonal Antibody for Mouse E3 ubiquitin-protein ligase TRIM32
    Polyclonal Antibody for Mouse E3 ubiquitin-protein ligase TRIM32
    Monoclonal Antibody for Mouse E3 ubiquitin-protein ligase TRIM32
    Monoclonal Antibody for Mouse E3 ubiquitin-protein ligase TRIM32
    Protein for Mouse E3 ubiquitin-protein ligase TRIM32
    Protein for Mouse E3 ubiquitin-protein ligase TRIM32

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties."
      Horn E.J. , Albor A. , Liu Y. , El-Hizawi S. , Vanderbeek G.E. , Babcock M. , Bowden G.T. , Hennings H. , Lozano G. , Weinberg W.C. , Kulesz-Martin M.
      Carcinogenesis25:157-167(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;SUBCELLULAR LOCATION;UBIQUITINATION
      tissue: Testis.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Retina.
    4. 4.
      "The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB."
      Albor A. , El-Hizawi S. , Horn E.J. , Laederich M. , Frosk P. , Wrogemann K. , Kulesz-Martin M.
      J. Biol. Chem.281:25850-25866(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH PIAS4
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