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Index > Protein center > TRIM56(Gene name) > Human
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  • TRIM56 (Gene name),
  • E3 ubiquitin-protein ligase TRIM56 (Protein name ),  TRI56_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    TRIM56(RNF109);
    Protein name:
    E3 ubiquitin-protein ligase TRIM56;
    Alternative:
    Tripartite motif-containing protein 56;RING finger protein 109;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with TMEM173/STING.
    Function:
    E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked polyubiquitination of TMEM173/STING, thereby playing a key role in innate immunity. TMEM173/STING 'Lys-63'-linked ubiquitination activates the production of type I interferon IFN-beta following detection of pathogen- and host-derived double-stranded DNA.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    755
    Sequence:
    50:
    MVSHGSSPSL | LEALSSDFLA | CKICLEQLRA | PKTLPCLHTY | CQDCLAQLAD | 
    100:
    GGRVRCPECR | ETVPVPPEGV | ASFKTNFFVN | GLLDLVKARA | CGDLRAGKPA | 
    150:
    CALCPLVGGT | STGGPATARC | LDCADDLCQA | CADGHRCTRQ | THTHRVVDLV | 
    200:
    GYRAGWYDEE | ARERQAAQCP | QHPGEALRFL | CQPCSQLLCR | ECRLDPHLDH | 
    250:
    PCLPLAEAVR | ARRPGLEGLL | AGVDNNLVEL | EAARRVEKEA | LARLREQAAR | 
    300:
    VGTQVEEAAE | GVLRALLAQK | QEVLGQLRAH | VEAAEEAARE | RLAELEGREQ | 
    350:
    VARAAAAFAR | RVLSLGREAE | ILSLEGAIAQ | RLRQLQGCPW | APGPAPCLLP | 
    400:
    QLELHPGLLD | KNCHLLRLSF | EEQQPQKDGG | KDGAGTQGGE | ESQSRREDEP | 
    450:
    KTERQGGVQP | QAGDGAQTPK | EEKAQTTREE | GAQTLEEDRA | QTPHEDGGPQ | 
    500:
    PHRGGRPNKK | KKFKGRLKSI | SREPSPALGP | NLDGSGLLPR | PIFYCSFPTR | 
    550:
    MPGDKRSPRI | TGLCPFGPRE | ILVADEQNRA | LKRFSLNGDY | KGTVPVPEGC | 
    600:
    SPCSVAALQS | AVAFSASARL | YLINPNGEVQ | WRRALSLSQA | SHAVAALPSG | 
    650:
    DRVAVSVAGH | VEVYNMEGSL | ATRFIPGGKA | SRGLRALVFL | TTSPQGHFVG | 
    700:
    SDWQQNSVVI | CDGLGQVVGE | YKGPGLHGCQ | PGSVSVDKKG | YIFLTLREVN | 
    750:
    KVVILDPKGS | LLGDFLTAYH | GLEKPRVTTM | VDGRYLVVSL | SNGTIHIFRV | 
    755:
    RSPDS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    Pfam:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human E3 ubiquitin-protein ligase TRIM56
    ELISA Kit for Human E3 ubiquitin-protein ligase TRIM56
    ELISA Kit for Human E3 ubiquitin-protein ligase TRIM56
    CLIA Kit for Human E3 ubiquitin-protein ligase TRIM56
    CLIA Kit for Human E3 ubiquitin-protein ligase TRIM56
    CLIA Kit for Human E3 ubiquitin-protein ligase TRIM56
    Polyclonal Antibody for Human E3 ubiquitin-protein ligase TRIM56
    Polyclonal Antibody for Human E3 ubiquitin-protein ligase TRIM56
    Polyclonal Antibody for Human E3 ubiquitin-protein ligase TRIM56
    Monoclonal Antibody for Human E3 ubiquitin-protein ligase TRIM56
    Monoclonal Antibody for Human E3 ubiquitin-protein ligase TRIM56
    Monoclonal Antibody for Human E3 ubiquitin-protein ligase TRIM56
    Protein for Human E3 ubiquitin-protein ligase TRIM56
    Protein for Human E3 ubiquitin-protein ligase TRIM56
    Protein for Human E3 ubiquitin-protein ligase TRIM56

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 429-755 (ISOFORM 1)
      tissue: Spleen.
      tissue: Thyroid.
    2. 2.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Lymph.
      tissue: Placenta.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 572-755 (ISOFORM 1)
      tissue: Lymph node.
    5. 5.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-475;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    6. 6.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-418; THR-442 AND SER-475;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
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