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Index > Protein center > Trim72(Gene name) > Rat
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  • Trim72 (Gene name),
  • Tripartite motif-containing protein 72 (Protein name ),  TRI72_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Trim72(Mg53);
    Protein name:
    Tripartite motif-containing protein 72;
    Alternative:
    Mitsugumin-53(Mg53);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homooligomer; disulfide-linked. Interacts with DYSF and CAV3.
    Function:
    Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.
    Subcellular Location:
    Cell membrane sarcolemma Cytoplasmic vesicle membrane Tethered to plasma membrane and cytoplasmic vesicles via its interaction with phosphatidylserine.
    Protein Attributes:
    Sequence length:
    477
    Sequence:
    50:
    MSTAPGLLRQ | ELSCPLCLQL | FDAPVTAECG | HSFCRACLIR | VAGEPADDGT | 
    100:
    VACPCCQAST | RPQALSTNLQ | LARLVEGLAQ | VPQGHCEEHL | DPLSIYCEQD | 
    150:
    RTLVCGVCAS | LGSHRGHRLL | PAAEAHARLK | TQLPQQKAQL | QEACMRKEKS | 
    200:
    VAVLEHQLVE | VEETVRQFRG | AVGEQLGKMR | MFLAALESSL | DREAERVRGE | 
    250:
    AGVALRRELS | SLNSYLEQLR | QMEKVLEEVA | DKPQTEFLMK | FCLVTSRLQK | 
    300:
    ILSESPPPAR | LDIQLPVISD | DFKFQVWKKM | FRALMPELEE | LTFDPSSAHP | 
    350:
    SLVVSASGRR | VECSEQKAPP | AGEDTCQFDK | TVAVVAKQLL | SQGEHYWEVE | 
    400:
    VGDKPRWALG | VMAADASRRG | RLHAVPSQGL | WLLGLRDGKI | LEAHVEAKEP | 
    450:
    RALRTPERPP | ARIGLYLSFA | DGVLTFYDAS | NTDALTPLFS | FHERLPGPVY | 
    477:
    PMFDVCWHDK | GKNSQPLLLV | GPDSEQA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Tripartite motif-containing protein 72
    Cat.:
    E3671r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Tripartite motif-containing protein 72
    Cat.:
    E3671h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Tripartite motif-containing protein 72
    Cat.:
    E3671m
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    MSDS:
    Please sign in first.
    Packing:
    96T
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    ELISA Kit for Rat Tripartite motif-containing protein 72
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Tripartite motif-containing protein 72
    Cat.:
    U3671r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Tripartite motif-containing protein 72
    Cat.:
    U3671h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Tripartite motif-containing protein 72
    Cat.:
    U3671m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Tripartite motif-containing protein 72
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Rat Tripartite motif-containing protein 72
    Cat.:
    P3671Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Tripartite motif-containing protein 72
    Cat.:
    P3671Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Tripartite motif-containing protein 72
    Polyclonal Antibody for Rat Tripartite motif-containing protein 72
    Cat.:
    P3671Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Tripartite motif-containing protein 72
    Monoclonal Antibody for Rat Tripartite motif-containing protein 72
    Monoclonal Antibody for Rat Tripartite motif-containing protein 72
    Monoclonal Antibody for Rat Tripartite motif-containing protein 72
    Protein for Rat Tripartite motif-containing protein 72
    Protein for Rat Tripartite motif-containing protein 72
    Protein for Rat Tripartite motif-containing protein 72
    Protein for Rat Tripartite motif-containing protein 72

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Heart.
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