Gene name:
Tyrp1 (Tyrp-1) ;
Protein name:
5,6-dihydroxyindole-2-carboxylic acid oxidase (DHICA oxidase) ;
Alternative:
Catalase B ;Brown locus protein ;Tyrosinase-related protein 1 (TRP;TRP-1;TRP1) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.
Subcellular Location:
Melanosome membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MKSYNVLPLA | YISLFLMLFY | QVWAQFPREC | ANIEALRRGV | CCPDLLPSSG |
100:
PGTDPCGSSS | GRGRCVAVIA | DSRPHSRHYP | HDGKDDREAW | PLRFFNRTCQ |
150:
CNDNFSGHNC | GTCRPGWRGA | ACNQKILTVR | RNLLDLSPEE | KSHFVRALDM |
200:
AKRTTHPQFV | IATRRLEDIL | GPDGNTPQFE | NISVYNYFVW | THYYSVKKTF |
250:
LGTGQESFGD | VDFSHEGPAF | LTWHRYHLLQ | LERDMQEMLQ | EPSFSLPYWN |
300:
FATGKNVCDV | CTDDLMGSRS | NFDSTLISPN | SVFSQWRVVC | ESLEEYDTLG |
350:
TLCNSTEGGP | IRRNPAGNVG | RPAVQRLPEP | QDVTQCLEVR | VFDTPPFYSN |
400:
STDSFRNTVE | GYSAPTGKYD | PAVRSLHNLA | HLFLNGTGGQ | THLSPNDPIF |
450:
VLLHTFTDAV | FDEWLRRYNA | DISTFPLENA | PIGHNRQYNM | VPFWPPVTNT |
500:
EMFVTAPDNL | GYAYEVQWPG | QEFTVSEIIT | IAVVAALLLV | AAIFGVASCL |
537:
IRSRSTKNEA | NQPLLTDHYQ | RYAEDYEELP | NPNHSMV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Bovine
Chicken
ELISA Kit for Mouse DHICA oxidase
ELISA Kit for Mouse DHICA oxidase
ELISA Kit for Mouse DHICA oxidase
ELISA Kit for Mouse DHICA oxidase
CLIA Kit for Mouse DHICA oxidase
CLIA Kit for Mouse DHICA oxidase
CLIA Kit for Mouse DHICA oxidase
CLIA Kit for Mouse DHICA oxidase
Polyclonal Antibody for Mouse DHICA oxidase
Polyclonal Antibody for Mouse DHICA oxidase
Polyclonal Antibody for Mouse DHICA oxidase
Polyclonal Antibody for Mouse DHICA oxidase
Monoclonal Antibody for Mouse DHICA oxidase
Monoclonal Antibody for Mouse DHICA oxidase
Monoclonal Antibody for Mouse DHICA oxidase
Monoclonal Antibody for Mouse DHICA oxidase
Protein for Mouse DHICA oxidase
Protein for Mouse DHICA oxidase
Protein for Mouse DHICA oxidase
Protein for Mouse DHICA oxidase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Melanoma .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
tissue :
Eye .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION OF PROTEIN
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : POSSIBLE FUNCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : POSSIBLE FUNCTION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
7.
"BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles."
Setty S.R.
,
Tenza D.
,
Truschel S.T.
,
Chou E.
,
Sviderskaya E.V.
,
Theos A.C.
,
Lamoreux M.L.
,
Di Pietro S.M.
,
Starcevic M.
,
Bennett D.C.
,
Dell'Angelica E.C.
,
Raposo G.
,
Marks M.S.
Mol. Biol. Cell18:768-780(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS BROWN TYR-110 AND HIS-326