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Index > Protein center > Tyrp1(Gene name) > Mouse
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  • Tyrp1 (Gene name),
  • 5,6-dihydroxyindole-2-carboxylic acid oxidase (Protein name ),  TYRP1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Tyrp1(Tyrp-1);
    Protein name:
    5,6-dihydroxyindole-2-carboxylic acid oxidase(DHICA oxidase);
    Alternative:
    Catalase B;Brown locus protein;Tyrosinase-related protein 1(TRP;TRP-1;TRP1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized.
    Subcellular Location:
    Melanosome membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    537
    Sequence:
    50:
    MKSYNVLPLA | YISLFLMLFY | QVWAQFPREC | ANIEALRRGV | CCPDLLPSSG | 
    100:
    PGTDPCGSSS | GRGRCVAVIA | DSRPHSRHYP | HDGKDDREAW | PLRFFNRTCQ | 
    150:
    CNDNFSGHNC | GTCRPGWRGA | ACNQKILTVR | RNLLDLSPEE | KSHFVRALDM | 
    200:
    AKRTTHPQFV | IATRRLEDIL | GPDGNTPQFE | NISVYNYFVW | THYYSVKKTF | 
    250:
    LGTGQESFGD | VDFSHEGPAF | LTWHRYHLLQ | LERDMQEMLQ | EPSFSLPYWN | 
    300:
    FATGKNVCDV | CTDDLMGSRS | NFDSTLISPN | SVFSQWRVVC | ESLEEYDTLG | 
    350:
    TLCNSTEGGP | IRRNPAGNVG | RPAVQRLPEP | QDVTQCLEVR | VFDTPPFYSN | 
    400:
    STDSFRNTVE | GYSAPTGKYD | PAVRSLHNLA | HLFLNGTGGQ | THLSPNDPIF | 
    450:
    VLLHTFTDAV | FDEWLRRYNA | DISTFPLENA | PIGHNRQYNM | VPFWPPVTNT | 
    500:
    EMFVTAPDNL | GYAYEVQWPG | QEFTVSEIIT | IAVVAALLLV | AAIFGVASCL | 
    537:
    IRSRSTKNEA | NQPLLTDHYQ | RYAEDYEELP | NPNHSMV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    SMR:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse DHICA oxidase
    Cat.:
    E9854m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse DHICA oxidase
    Cat.:
    E9854h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse DHICA oxidase
    Cat.:
    E9854b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse DHICA oxidase
    Cat.:
    E9854c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse DHICA oxidase
    Cat.:
    U9854c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse DHICA oxidase
    Cat.:
    U9854h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse DHICA oxidase
    Cat.:
    U9854m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse DHICA oxidase
    Cat.:
    U9854b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse DHICA oxidase
    Cat.:
    P9854Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse DHICA oxidase
    Polyclonal Antibody for Mouse DHICA oxidase
    Polyclonal Antibody for Mouse DHICA oxidase
    Cat.:
    P9854Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse DHICA oxidase
    Monoclonal Antibody for Mouse DHICA oxidase
    Monoclonal Antibody for Mouse DHICA oxidase
    Monoclonal Antibody for Mouse DHICA oxidase
    Protein for Mouse DHICA oxidase
    Protein for Mouse DHICA oxidase
    Protein for Mouse DHICA oxidase
    Protein for Mouse DHICA oxidase

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and expression of cDNA encoding mouse tyrosinase."
      Shibahara S. , Tomita Y. , Sakakura T. , Nager C. , Chaudhuri B. , Mueller R.
      Nucleic Acids Res.14:2413-2427(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Melanoma.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Eye.
    3. 3.
      "A cDNA encoding tyrosinase-related protein maps to the brown locus in mouse."
      Jackson I.J.
      Proc. Natl. Acad. Sci. U.S.A.85:4392-4396(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF PROTEIN
    4. 4.
      "Murine and human b locus pigmentation genes encode a glycoprotein (gp75) with catalase activity."
      Halaban R. , Moellmann G.
      Proc. Natl. Acad. Sci. U.S.A.87:4809-4813(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE FUNCTION
    5. 5.
      "The mouse brown (b) locus protein has dopachrome tautomerase activity and is located in lysosomes in transfected fibroblasts."
      Winder A.J. , Wittbjer A. , Rosengren E. , Rorsman H.
      J. Cell Sci.106:153-166(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE FUNCTION
    6. 6.
      "Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis."
      Kobayashi T. , Urabe K. , Winder A. , Jimenez-Cervantes C. , Imokawa G. , Brewington T. , Solano F. , Garcia-Borron J.C. , Hearing V.J.
      EMBO J.13:5818-5825(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organelles."
      Setty S.R. , Tenza D. , Truschel S.T. , Chou E. , Sviderskaya E.V. , Theos A.C. , Lamoreux M.L. , Di Pietro S.M. , Starcevic M. , Bennett D.C. , Dell'Angelica E.C. , Raposo G. , Marks M.S.
      Mol. Biol. Cell18:768-780(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    8. 8.
      "The molecular basis of brown, an old mouse mutation, and of an induced revertant to wild type."
      Zdarsky E. , Favor J. , Jackson I.J.
      Genetics126:443-449(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS BROWN TYR-110 AND HIS-326
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