Protein name:
Splicing factor U2AF 35 kDa subunit ;
Alternative:
U2 snRNP auxiliary factor small subunit ;U2 auxiliary factor 35 kDa subunit ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Identified in the spliceosome C complex. Heterodimer with U2AF2. Interacts with ZRANB2 (By similarity). Interacts (via RS domain) with PHF5A (via N-terminus).
Function:
Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron.
Subcellular Location:
Nucleus
Nucleus speckle
Protein Attributes:
50:
MAEYLASIFG | TEKDKVNCSF | YFKIGACRHG | DRCSRLHNKP | TFSQTIALLN |
100:
IYRNPQNSSQ | SADGLRCAVS | DVEMQEHYDE | FFEEVFTEME | EKYGEVEEMN |
150:
VCDNLGDHLV | GNVYVKFRRE | EDAEKAVIDL | NNRWFNGQPI | HAELSPVTDF |
200:
REACCRQYEM | GECTRGGFCN | FMHLKPISRE | LRRELYGRRR | KKHRSRSRSR |
239:
ERRSRSRDRG | RGGGGGGGGG | GGRERDRRRS | RDRERSGRF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Pig
Mouse
ELISA Kit for Mouse Splicing factor U2AF 35 kDa subunit
ELISA Kit for Mouse Splicing factor U2AF 35 kDa subunit
ELISA Kit for Mouse Splicing factor U2AF 35 kDa subunit
ELISA Kit for Mouse Splicing factor U2AF 35 kDa subunit
CLIA Kit for Mouse Splicing factor U2AF 35 kDa subunit
CLIA Kit for Mouse Splicing factor U2AF 35 kDa subunit
CLIA Kit for Mouse Splicing factor U2AF 35 kDa subunit
CLIA Kit for Mouse Splicing factor U2AF 35 kDa subunit
Polyclonal Antibody for Mouse Splicing factor U2AF 35 kDa subunit
Polyclonal Antibody for Mouse Splicing factor U2AF 35 kDa subunit
Polyclonal Antibody for Mouse Splicing factor U2AF 35 kDa subunit
Polyclonal Antibody for Mouse Splicing factor U2AF 35 kDa subunit
Monoclonal Antibody for Mouse Splicing factor U2AF 35 kDa subunit
Monoclonal Antibody for Mouse Splicing factor U2AF 35 kDa subunit
Monoclonal Antibody for Mouse Splicing factor U2AF 35 kDa subunit
Monoclonal Antibody for Mouse Splicing factor U2AF 35 kDa subunit
Protein for Mouse Splicing factor U2AF 35 kDa subunit
Protein for Mouse Splicing factor U2AF 35 kDa subunit
Protein for Mouse Splicing factor U2AF 35 kDa subunit
Protein for Mouse Splicing factor U2AF 35 kDa subunit
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
strain :
NOD .
tissue :
Bone marrow .
tissue :
Small intestine .
tissue :
Thymus .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Mammary tumor .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH PHF5A;SUBCELLULAR LOCATION;TISSUE SPECIFICITY