Gene name:
UBA5 (UBE1DC1) ;
Protein name:
Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) ;
Alternative:
UFM1-activating enzyme ;ThiFP1 ;Ubiquitin-activating enzyme E1 domain-containing protein 1 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
E1-like enzyme which activates UFM1 and SUMO2.
Subcellular Location:
Cytoplasm
Nucleus
Localizes mainly in cytoplasm, while it mainly localizes to the nucleus in presence of SUMO2.
Protein Attributes:
50:
MAESVERLQQ | RVQELERELA | QERSLQVPRS | GDGGGGRVRI | EKMSSEVVDS |
100:
NPYSRLMALK | RMGIVSDYEK | IRTFAVAIVG | VGGVGSVTAE | MLTRCGIGKL |
150:
LLFDYDKVEL | ANMNRLFFQP | HQAGLSKVQA | AEHTLRNINP | DVLFEVHNYN |
200:
ITTVENFQHF | MDRISNGGLE | EGKPVDLVLS | CVDNFEARMT | INTACNELGQ |
250:
TWMESGVSEN | AVSGHIQLII | PGESACFACA | PPLVVAANID | EKTLKREGVC |
300:
AASLPTTMGV | VAGILVQNVL | KFLLNFGTVS | FYLGYNAMQD | FFPTMSMKPN |
350:
PQCDDRNCRK | QQEEYKKKVA | ALPKQEVIQE | EEEIIHEDNE | WGIELVSEVS |
400:
EEELKNFSGP | VPDLPEGITV | AYTIPKKQED | SVTELTVEDS | GESLEDLMAK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Bovine
Chicken
ELISA Kit for Human Ubiquitin-activating enzyme 5
ELISA Kit for Human Ubiquitin-activating enzyme 5
ELISA Kit for Human Ubiquitin-activating enzyme 5
ELISA Kit for Human Ubiquitin-activating enzyme 5
ELISA Kit for Human Ubiquitin-activating enzyme 5
CLIA Kit for Human Ubiquitin-activating enzyme 5
CLIA Kit for Human Ubiquitin-activating enzyme 5
CLIA Kit for Human Ubiquitin-activating enzyme 5
CLIA Kit for Human Ubiquitin-activating enzyme 5
CLIA Kit for Human Ubiquitin-activating enzyme 5
Polyclonal Antibody for Human Ubiquitin-activating enzyme 5
Polyclonal Antibody for Human Ubiquitin-activating enzyme 5
Polyclonal Antibody for Human Ubiquitin-activating enzyme 5
Polyclonal Antibody for Human Ubiquitin-activating enzyme 5
Polyclonal Antibody for Human Ubiquitin-activating enzyme 5
Monoclonal Antibody for Human Ubiquitin-activating enzyme 5
Monoclonal Antibody for Human Ubiquitin-activating enzyme 5
Monoclonal Antibody for Human Ubiquitin-activating enzyme 5
Monoclonal Antibody for Human Ubiquitin-activating enzyme 5
Monoclonal Antibody for Human Ubiquitin-activating enzyme 5
Protein for Human Ubiquitin-activating enzyme 5
Protein for Human Ubiquitin-activating enzyme 5
Protein for Human Ubiquitin-activating enzyme 5
Protein for Human Ubiquitin-activating enzyme 5
Protein for Human Ubiquitin-activating enzyme 5
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;MUTAGENESIS OF CYS-250
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Testis .
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[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Colon .
tissue :
Teratocarcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
Mural R.J.
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Lung .
8.
"UBE1DC1, an ubiquitin-activating enzyme, activates two different ubiquitin-like proteins."
Zheng M.
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Gu X.
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J. Cell. Biochem.104:2324-2334(2008)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;ALTERNATIVE SPLICING (ISOFORMS 1 AND 2);SUBCELLULAR LOCATION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-45;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .
11.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V.
,
Vermeulen M.
,
Santamaria A.
,
Kumar C.
,
Miller M.L.
,
Jensen L.J.
,
Gnad F.
,
Cox J.
,
Jensen T.S.
,
Nigg E.A.
,
Brunak S.
,
Mann M.
Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-358;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 57-329 IN COMPLEX WITH ATP AND ZINC;FUNCTION;ACTIVE SITE