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Index > Protein center > Usp16(Gene name) > Mouse
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  • Usp16 (Gene name),
  • Ubiquitin carboxyl-terminal hydrolase 16 (Protein name ),  UBP16_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Usp16;
    Protein name:
    Ubiquitin carboxyl-terminal hydrolase 16;
    Alternative:
    Ubiquitin thiolesterase 16;Deubiquitinating enzyme 16;Ubiquitin-specific-processing protease 16;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Specifically deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-10' of histone H3, and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    825
    Sequence:
    50:
    MGKKRTKGRS | APDTVASESA | EPVCRHLRKG | LEQGNLKKAL | VNVEWNICQD | 
    100:
    CKTDNKVKDK | PEEEAEDPSV | WLCLKCGHQG | CGRDSQEQHA | LKHYTTPRSE | 
    150:
    PHYLVLSLDN | WSVWCYKCDE | EVKYCSSNRL | GQVVDYVRKQ | AGVRTSKPAE | 
    200:
    KNNGHIELEN | KKLEKESKNE | QEKEKSENLA | KETIPMDSAS | QITVKGLSNL | 
    250:
    GNTCFFNAVM | QNLSQTPVLR | ELLKEVKMSG | TIVKIEPPDL | ALTEPLEVNL | 
    300:
    EPPGPLTLAM | SQFLSEMQEN | KKRVVTPKEL | FSQVCKKATR | FKGYQQQDSQ | 
    350:
    ELLRYLLDGM | RAEEHQRVSK | GILKAFGNST | EKLDEEVKNK | VKDYEKKKAI | 
    400:
    PSFVDRIFGG | ELTSTIMCDE | CRTVSLVHES | FLDLSLPVLD | DQSGKKSIND | 
    450:
    KNVKMTMEEE | DKDSEEEKDD | SYMKSRSDLP | SGTSKHLQKK | AKKQAKKQAK | 
    500:
    NQRRQQKIQE | RFLHFNELCA | TDYTEDNERE | ADTALAGEVE | VDTDSTHGSQ | 
    550:
    EEATQIELSV | NQKDLDGQES | MIERTPDVQE | SPEDLGVKSA | NTESDLGIVT | 
    600:
    PAPECPRDFN | GAFLEERTSG | ELDIINGLKN | LNLNAAVDPD | EINIEIPNDS | 
    650:
    HSAPKVYEVM | NEDPETAFCT | LANREAFSTD | ECSIQHCLYQ | FTRNEKLQDA | 
    700:
    NKLLCEVCSR | RQCNGPKANI | KGDRRHVYTN | AKKQMLVSLA | PPVLTLHLKR | 
    750:
    FQQAGFNLRK | VNKHIKFPEI | LDLAPFCTLK | CKNVAEESTR | VLYSLYGVVE | 
    800:
    HSGTMRSGHY | TAYAKERTAS | CHLSNLVLHG | DIPQDCEMES | TKGQWFHISD | 
    825:
    THVQAVPITK | VLNSQAYLLF | YERIL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    SMR:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Ubiquitin carboxyl-terminal hydrolase 16
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    ELISA Kit for Mouse Ubiquitin carboxyl-terminal hydrolase 16
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    Packing:
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    ELISA Kit for Mouse Ubiquitin carboxyl-terminal hydrolase 16
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    ELISA Kit for Mouse Ubiquitin carboxyl-terminal hydrolase 16
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    Packing:
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    CLIA Kit for Mouse Ubiquitin carboxyl-terminal hydrolase 16
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    U11580m
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    Packing:
    96T
    CLIA Kit for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Cat.:
    U11580b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Cat.:
    U11580h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Cat.:
    U11580r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Ubiquitin carboxyl-terminal hydrolase 16
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    Packing:
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    Polyclonal Antibody for Mouse Ubiquitin carboxyl-terminal hydrolase 16
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    P11580Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Ubiquitin carboxyl-terminal hydrolase 16
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    P11580Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Monoclonal Antibody for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Monoclonal Antibody for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Monoclonal Antibody for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Monoclonal Antibody for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Protein for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Protein for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Protein for Mouse Ubiquitin carboxyl-terminal hydrolase 16
    Protein for Mouse Ubiquitin carboxyl-terminal hydrolase 16

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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Czech II.
      strain: FVB/N.
      tissue: Mammary tumor.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-520;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    6. 6.
      "The Aurora B kinase and the Polycomb protein Ring1B combine to regulate active promoters in quiescent lymphocytes."
      Frangini A. , Sjoberg M. , Roman-Trufero M. , Dharmalingam G. , Haberle V. , Bartke T. , Lenhard B. , Malumbres M. , Vidal M. , Dillon N.
      Mol. Cell51:647-661(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: UP-REGULATION IN DOWN SYNDROME MODELS
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