USP20 ELISA Kit for Bovine(Bos taurus) | EIAab.comUSP20 ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > USP20(Gene name) > Bovine

USP20 (Gene name),

Ubiquitin carboxyl-terminal hydrolase 20 (Protein name ), UBP20_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

USP20;

Protein name:

Ubiquitin carboxyl-terminal hydrolase 20;

Alternative:

Ubiquitin thiolesterase 20;Deubiquitinating enzyme 20;Ubiquitin-specific-processing protease 20;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Interacts with VHL, leading to its ubiquitination and subsequent degradation. Interacts with DIO2 and HIF1A.

Function:

Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Subcellular Location:

Cytoplasm perinuclear region

Protein Attributes:

Sequence length:

912

Sequence:

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912:

GEQKIEAETR | AL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

A7Z056

KEGG:

bta:505839

Pfam:

PF06337

UniGene:

Bt.26746

SMR:

A7Z056

STRING:

9913.ENSBTAP00000027070

Uniprot:

A7Z056

FOR

ELISA Kit for Bovine Ubiquitin carboxyl-terminal hydrolase 20

CLIA Kit for Bovine Ubiquitin carboxyl-terminal hydrolase 20

Polyclonal Antibody for Bovine Ubiquitin carboxyl-terminal hydrolase 20

Monoclonal Antibody for Bovine Ubiquitin carboxyl-terminal hydrolase 20

Protein for Bovine Ubiquitin carboxyl-terminal hydrolase 20

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2007-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Uterus.

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