USP2 ELISA Kit for Bovine(Bos taurus) | EIAab.comUSP2 ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > USP2(Gene name) > Bovine

USP2 (Gene name),

Ubiquitin carboxyl-terminal hydrolase 2 (Protein name ), UBP2_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

USP2(UBP41);

Protein name:

Ubiquitin carboxyl-terminal hydrolase 2;

Alternative:

Deubiquitinating enzyme 2;41 kDa ubiquitin-specific protease;Ubiquitin-specific-processing protease 2;Ubiquitin thiolesterase 2;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Homooligomer (By similarity). Found in trimeric complex with MDM2 and MDM4 and UPB2. Interacts with CCND1; the interaction is direct and promotes its stabilization by antagonizing ubiquitin-dependent degradation. Interacts (via N-terminus and C-terminus) with MDM2. Interacts with MDM4.

Function:

Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Possesses both ubiquitin-specific peptidase and isopeptidase activities. Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4. Plays a role in the G1/S cell-cycle progression in normal and cancer cells. Plays a role in the regulation of myogenic differentiation of embryonic muscle cells.

Subcellular Location:

Cytoplasm Cytoplasm perinuclear region Localizes in the spermatid head in late-elongating spermatids in the thin area between the outer acrosomal membrane and the plasma membrane.

Protein Attributes:

Sequence length:

606

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

606:

SPPSRM

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9913.ENSBTAP00000012857

KEGG:

bta:522980

SMR:

Q2KHV7

Pfam:

PF00443

UniGene:

Bt.21721

Uniprot:

Q2KHV7

FOR

ELISA Kit for Bovine Ubiquitin carboxyl-terminal hydrolase 2

CLIA Kit for Bovine Ubiquitin carboxyl-terminal hydrolase 2

Polyclonal Antibody for Bovine Ubiquitin carboxyl-terminal hydrolase 2

Monoclonal Antibody for Bovine Ubiquitin carboxyl-terminal hydrolase 2

Protein for Bovine Ubiquitin carboxyl-terminal hydrolase 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2006-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Heart ventricle.

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