UBXN6 ELISA Kit for Human(Homo sapiens) | EIAab.comUBXN6 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > UBXN6(Gene name) > Human

UBXN6 (Gene name),

UBX domain-containing protein 6 (Protein name ), UBXN6_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

UBXN6(UBXD1;UBXDC2);

Protein name:

UBX domain-containing protein 6;

Alternative:

UBX domain-containing protein 1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with VCP through the PUB domain. Interacts with SYVN1, HERPUD1, MDM2 and USP7.

Function:

Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation.

Subcellular Location:

Cytoplasm Nucleus Cytoplasm cytoskeleton centrosome Localizes at the centrosome both in interphase and during mitosis.

Protein Attributes:

Sequence length:

441

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

441:

VPSALLTFSW | DMAVLEDIKA | AGAEPDSILK | PELLSAIEKL | L

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9BZV1

MIM:

611946

KEGG:

hsa:80700

Pfam:

PF09409

SMR:

Q9BZV1

STRING:

9606.ENSP00000301281

UniGene:

Hs.435255

Uniprot:

Q9BZV1

FOR

ELISA Kit for Human UBX domain-containing protein 6

CLIA Kit for Human UBX domain-containing protein 6

Polyclonal Antibody for Human UBX domain-containing protein 6

Monoclonal Antibody for Human UBX domain-containing protein 6

Protein for Human UBX domain-containing protein 6

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Identification and characterization of UBXD1, a novel UBX domain-containing gene on human chromosome 19p13, and its mouse ortholog."
Carim-Todd L. , Escarceller M. , Estivill X. , Sumoy L.
Biochim. Biophys. Acta1517:298-301(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
2.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Skin.
tissue: Uterus.
4.

"Ubxd1 is a novel co-factor of the human p97 ATPase."
Madsen L. , Andersen K.M. , Prag S. , Moos T. , Semple C.A. , Seeger M. , Hartmann-Petersen R.
Int. J. Biochem. Cell Biol.40:2927-2942(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH VCP; SYVN1 AND HERPUD1;SUBCELLULAR LOCATION
5.

"AAA ATPase p97 and adaptor UBXD1 suppress MDM2 ubiquitination and degradation and promote constitutive p53 turnover."
Zweitzig D.R. , Shcherbik N. , Haines D.S.
Mol. Biol. Cell19:5029-5029(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH VCP; MDM2 AND USP7
6.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-96;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
7.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
8.

"The general definition of the p97/valosin-containing protein (VCP)-interacting motif (VIM) delineates a new family of p97 cofactors."
Stapf C. , Cartwright E. , Bycroft M. , Hofmann K. , Buchberger A.
J. Biol. Chem.286:38670-38678(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH VCP;VIM MOTIF
9.

"A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity."
Cloutier P. , Lavallee-Adam M. , Faubert D. , Blanchette M. , Coulombe B.
PLoS Genet.9:E1003210-E1003210(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH VCPKMT

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