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Index > Protein center > UCHL3(Gene name) > Pig
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  • UCHL3 (Gene name),
  • Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Protein name ),  UCHL3_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    UCHL3;
    Protein name:
    Ubiquitin carboxyl-terminal hydrolase isozyme L3(UCH-L3);
    Alternative:
    Ubiquitin thioesterase L3;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    Preferentially binds diubiquitin; the interaction does not hydrolyze diubiquitin but, in vitro, inhibits the hydrolyzing activity on other substrates.
    Function:
    Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3". Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory. Can hydrolyze UBB(+1), a mutated form of ubiquitin which is not effectively degraded by the proteasome.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    230
    Sequence:
    50:
    MEGQRWLPLE | ANPEVTNQFL | KQLGLHPNWQ | FVDVYGMDPE | LLSMVPRPVC | 
    100:
    AVLLLFPITE | KYEVFRTEEE | EKIKSQGQDV | TPSVYFMKQT | ISNACGTIGL | 
    150:
    IHAIANNKNK | MHFESGSTLK | KFLEESASMS | PDERARYLES | YDAIPVTHET | 
    200:
    SAHEGQTEAP | NIDEKVDLHF | IALVHVDGHL | YELDGRKPFP | INHGETSDET | 
    230:
    LLEDAIEVCK | KFMERDPDEL | RFNAIALSAA | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Pig UCH-L3
    ELISA Kit for Pig UCH-L3
    ELISA Kit for Pig UCH-L3
    ELISA Kit for Pig UCH-L3
    ELISA Kit for Pig UCH-L3
    CLIA Kit for Pig UCH-L3
    CLIA Kit for Pig UCH-L3
    CLIA Kit for Pig UCH-L3
    CLIA Kit for Pig UCH-L3
    CLIA Kit for Pig UCH-L3
    Polyclonal Antibody for Pig UCH-L3
    Polyclonal Antibody for Pig UCH-L3
    Polyclonal Antibody for Pig UCH-L3
    Polyclonal Antibody for Pig UCH-L3
    Polyclonal Antibody for Pig UCH-L3
    Monoclonal Antibody for Pig UCH-L3
    Monoclonal Antibody for Pig UCH-L3
    Monoclonal Antibody for Pig UCH-L3
    Monoclonal Antibody for Pig UCH-L3
    Monoclonal Antibody for Pig UCH-L3
    Protein for Pig UCH-L3
    Protein for Pig UCH-L3
    Protein for Pig UCH-L3
    Protein for Pig UCH-L3
    Protein for Pig UCH-L3

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    Precision
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    References
    1. 1.
      Liu G.Y.
      Submitted (2006-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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