UGT1A7 ELISA Kit for Human(Homo sapiens) | EIAab.comUGT1A7 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > UGT1A7(Gene name) > Human

UGT1A7 (Gene name),

UDP-glucuronosyltransferase 1-7 (Protein name ), UD17_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

UGT1A7(GNT1;UGT1);

Protein name:

UDP-glucuronosyltransferase 1-7(UDPGT 1-7;UGT1*7;UGT1-07;UGT1.7);

Alternative:

UDP-glucuronosyltransferase 1A7;UDP-glucuronosyltransferase 1-G(UGT-1G;UGT1G);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.

Subcellular Location:

Microsome Endoplasmic reticulum membrane Single-pass membrane protein

Protein Attributes:

Sequence length:

530

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

530:

FITFKCCAYG | YRKCLGKKGR | VKKAHKSKTH |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.554822

MIM:

191740

SMR:

Q9HAW7

KEGG:

hsa:54577

Pfam:

PF00201

STRING:

9606.ENSP00000362525

String:

Q9HAW7

Uniprot:

Q9HAW7

FOR

ELISA Kit for Human UDPGT 1-7

CLIA Kit for Human UDPGT 1-7

Polyclonal Antibody for Human UDPGT 1-7

Monoclonal Antibody for Human UDPGT 1-7

Protein for Human UDPGT 1-7

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue."
Strassburg C.P. , Oldhafer K. , Manns M.P. , Tukey R.H.
Mol. Pharmacol.52:212-220(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
2.

"Thirteen UDP-glucuronosyltransferase genes are encoded at the human UGT1 gene complex locus."
Gong Q.H. , Cho J.W. , Huang T. , Potter C. , Gholami N. , Basu N.K. , Kubota S. , Carvalho S. , Pennington M.W. , Owens I.S. , Popescu N.C.
Pharmacogenetics11:357-368(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS LYS-129; LYS-131 AND ARG-208
3.

Guillemette C. , Levesque E. , Girard H. , Bernard O.
Submitted (2006-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);VARIANTS LYS-129 AND LYS-131
4.

"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Genetic diversity at the UGT1 locus is amplified by a novel 3' alternative splicing mechanism leading to nine additional UGT1A proteins that act as regulators of glucuronidation activity."
Girard H. , Levesque E. , Bellemare J. , Journault K. , Caillier B. , Guillemette C.
Pharmacogenet. Genomics17:1077-1089(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;ALTERNATIVE SPLICING;FUNCTION (ISOFORM 2);TISSUE SPECIFICITY
6.

"Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro."
Bellemare J. , Rouleau M. , Girard H. , Harvey M. , Guillemette C.
Drug Metab. Dispos.38:1785-1789(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;FUNCTION (ISOFORM 2);SUBUNIT
7.

"The relative protein abundance of UGT1A alternative splice variants as a key determinant of glucuronidation activity in vitro."
Rouleau M. , Roberge J. , Falardeau S.A. , Villeneuve L. , Guillemette C.
Drug Metab. Dispos.41:694-697(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
8.

"Structural heterogeneity at the UDP-glucuronosyltransferase 1 locus: functional consequences of three novel missense mutations in the human UGT1A7 gene."
Guillemette C. , Ritter J.K. , Auyeung D.J. , Kessler F.K. , Housman D.E.
Pharmacogenetics10:629-644(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LYS-129; LYS-131 AND ARG-208;CHARACTERIZATION OF ALLELES
9.

"Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population."
Menard V. , Girard H. , Harvey M. , Perusse L. , Guillemette C.
Hum. Mutat.30:677-687(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LYS-129; LYS-131 AND ARG-208

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