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Index > Protein center > UGT2B7(Gene name) > Human
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  • UGT2B7 (Gene name),
  • UDP-glucuronosyltransferase 2B7 (Protein name ),  UD2B7_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    UGT2B7(UGTB2B9);
    Protein name:
    UDP-glucuronosyltransferase 2B7(UDPGT 2B7);
    Alternative:
    UDP-glucuronosyltransferase 2B9(UDPGT 2B9);3,4-catechol estrogen-specific UDPGT;UDPGTh-2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Its unique specificity for 3,4-catechol estrogens and estriol suggests it may play an important role in regulating the level and activity of these potent and active estrogen metabolites.
    Subcellular Location:
    Microsome membrane Single-pass membrane protein Endoplasmic reticulum membrane Single-pass membrane protein
    Protein Attributes:
    Sequence length:
    529
    Sequence:
    50:
    MSVKWTSVIL | LIQLSFCFSS | GNCGKVLVWA | AEYSHWMNIK | TILDELIQRG | 
    100:
    HEVTVLASSA | SILFDPNNSS | ALKIEIYPTS | LTKTELENFI | MQQIKRWSDL | 
    150:
    PKDTFWLYFS | QVQEIMSIFG | DITRKFCKDV | VSNKKFMKKV | QESRFDVIFA | 
    200:
    DAIFPCSELL | AELFNIPFVY | SLSFSPGYTF | EKHSGGFIFP | PSYVPVVMSE | 
    250:
    LTDQMTFMER | VKNMIYVLYF | DFWFEIFDMK | KWDQFYSEVL | GRPTTLSETM | 
    300:
    GKADVWLIRN | SWNFQFPHPL | LPNVDFVGGL | HCKPAKPLPK | EMEDFVQSSG | 
    350:
    ENGVVVFSLG | SMVSNMTEER | ANVIASALAQ | IPQKVLWRFD | GNKPDTLGLN | 
    400:
    TRLYKWIPQN | DLLGHPKTRA | FITHGGANGI | YEAIYHGIPM | VGIPLFADQP | 
    450:
    DNIAHMKARG | AAVRVDFNTM | SSTDLLNALK | RVINDPSYKE | NVMKLSRIQH | 
    500:
    DQPVKPLDRA | VFWIEFVMRH | KGAKHLRVAA | HDLTWFQYHS | LDVIGFLLVC | 
    529:
    VATVIFIVTK | CCLFCFWKFA | RKAKKGKND
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    SMR:
    UniGene:
    Pfam:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human UDPGT 2B7
    ELISA Kit for Human UDPGT 2B7
    CLIA Kit for Human UDPGT 2B7
    CLIA Kit for Human UDPGT 2B7
    Polyclonal Antibody for Human UDPGT 2B7
    Polyclonal Antibody for Human UDPGT 2B7
    Monoclonal Antibody for Human UDPGT 2B7
    Monoclonal Antibody for Human UDPGT 2B7
    Protein for Human UDPGT 2B7
    Protein for Human UDPGT 2B7

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells. 3,4-catechol estrogens and estriol as primary substrates."
      Ritter J.K. , Sheen Y.Y. , Owens I.S.
      J. Biol. Chem.265:7900-7906(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Liver.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT TYR-268
      tissue: Kidney.
    3. 3.
      Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT TYR-268
      tissue: Kidney.
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT TYR-268
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT TYR-268
      tissue: Kidney.
    6. 6.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-68
      tissue: Liver.
    7. 7.
      "Crystal structure of the cofactor-binding domain of the human phase II drug-metabolism enzyme UDP-glucuronosyltransferase 2B7."
      Miley M.J. , Zielinska A.K. , Keenan J.E. , Bratton S.M. , Radominska-Pandya A. , Redinbo M.R.
      J. Mol. Biol.369:498-511(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 285-451;CATALYTIC ACTIVITY;FUNCTION TOWARDS STEROIDS;MUTAGENESIS OF SER-15; HIS-35; ASP-151; THR-373; HIS-374; ASN-378; GLY-379; ASP-398 AND GLN-399
    8. 8.
      "Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance."
      Bhasker C.R. , McKinnon W. , Stone A. , Lo A.C. , Kubota T. , Ishizaki T. , Miners J.O.
      Pharmacogenetics10:679-685(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT UGT2B7*2 TYR-268
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