E3 ubiquitin-protein ligase UHRF2 (Protein name
), UHRF2_MOUSE from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Gene name:
Uhrf2(Nirf);
Protein name:
E3 ubiquitin-protein ligase UHRF2;
Alternative:
Np95-like ring finger protein;NIRF;Nuclear zinc finger protein Np97;Nuclear protein 97;Ubiquitin-like-containing PHD and RING finger domains protein 2;Ubiquitin-like PHD and RING finger domain-containing protein 2;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Binds methylated CpG containing oligonucleotides. Interacts with PCNP, HDAC1 and inactive CDK2. Component of a complex at least composed of UHRF2, CDK2 and CCNE1.
Function:
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of PCNP. May participate in methylation-dependent transcriptional regulation. Important for G1/S transition. Overexpression causes G1 phase cell arrest.
ELISA Kit for Mouse E3 ubiquitin-protein ligase UHRF2
ELISA Kit for Mouse E3 ubiquitin-protein ligase UHRF2
CLIA Kit for Mouse E3 ubiquitin-protein ligase UHRF2
CLIA Kit for Mouse E3 ubiquitin-protein ligase UHRF2
Polyclonal Antibody for Mouse E3 ubiquitin-protein ligase UHRF2
Polyclonal Antibody for Mouse E3 ubiquitin-protein ligase UHRF2
Monoclonal Antibody for Mouse E3 ubiquitin-protein ligase UHRF2
Monoclonal Antibody for Mouse E3 ubiquitin-protein ligase UHRF2
Protein for Mouse E3 ubiquitin-protein ligase UHRF2
Protein for Mouse E3 ubiquitin-protein ligase UHRF2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"LMO2-induced T cell leukemias overexpress a novel gene, Uhr1, containing RING and PHD zinc fingers and an ubiquitin-like domain." Davenport J.W.
,
Fernandes E.R.
,
Neale G.A.M.
,
Goorha R.M.
Submitted (2000-06) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-195
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: FUNCTION;DNA-BINDING;INTERACTION WITH H3;SUBCELLULAR LOCATION;INDUCTION;MUTAGENESIS OF TYR-214 AND TYR-217