Ulk3 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comUlk3 ELISA Kit for Rat(Rattus norvegicus)

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Ulk3 (Gene name),

Serine/threonine-protein kinase ULK3 (Protein name ), ULK3_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ulk3;

Protein name:

Serine/threonine-protein kinase ULK3;

Alternative:

Unc-51-like kinase 3;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts (via protein kinase domain) with SUFU.

Function:

Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.

Subcellular Location:

Cytoplasm Localizes to pre-autophagosomal structure during cellular senescence.

Protein Attributes:

Sequence length:

472

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

472:

WEAESLDKEG | LSESVRSSCT | LQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

rno:691171

Pfam:

PF04212

UniGene:

Rn.198816

Uniprot:

D3ZHP7

FOR

ELISA Kit for Rat Serine/threonine-protein kinase ULK3

CLIA Kit for Rat Serine/threonine-protein kinase ULK3

Polyclonal Antibody for Rat Serine/threonine-protein kinase ULK3

Monoclonal Antibody for Rat Serine/threonine-protein kinase ULK3

Protein for Rat Serine/threonine-protein kinase ULK3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]

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