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Index > Protein center > Unc13d(Gene name) > Rat
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  • Unc13d (Gene name),
  • Protein unc-13 homolog D (Protein name ),  UN13D_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Unc13d(Unc13h4);
    Protein name:
    Protein unc-13 homolog D;
    Alternative:
    Munc13-4;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with RAB27A and DOC2A.
    Function:
    Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse. Regulates assembly of recycling and late endosomal structures, leading to the formation of an endosomal exocytic compartment that fuses with perforin-containing granules at the immunologic synapse and licences them for exocytosis. Regulates Ca(2+)-dependent secretory lysosome exocytosis in mast cells.
    Subcellular Location:
    Cytoplasm Membrane Peripheral membrane protein Late endosome Recycling endosome Lysosome Colocalizes with cytotoxic granules at the plasma membrane (By similarity). Localizes to endosomal exocytic vesicles.
    Protein Attributes:
    Sequence length:
    1088
    Sequence:
    50:
    MATHLSHPQR | RPPLLRQAVK | IRRRRVRDLQ | DPPPQATPEV | QVQSHHFSPE | 
    100:
    ERDLLYEEAL | YTVLHRLGQP | EPNHVKEASE | LLCYLQEAFQ | VQPEEHQQML | 
    150:
    QRVRELEKPI | FCLKATVKQA | KGILGKDVSG | FSDPYCLLGI | EQKVGVPEGS | 
    200:
    PVSRRRQKAV | VRHTIPEEET | HRTQVKTQTL | NPVWDETFIL | EFEDITNASF | 
    250:
    HLDMWDLDTV | ESVRHKLGEL | TDLHGLRRIF | KEARKDKGQD | DFLGNVMLRL | 
    300:
    QDLRCREDQW | FPLEPCTETY | PDRGQCHLQF | QFIHKRRATV | ASRSQPSYTV | 
    350:
    HFHLLQQLVS | HEVTQHQAGG | TSWGRIAESQ | AVTILFLHAT | QKDLSDFHQS | 
    400:
    MAQWLAYSRL | YQSLEFPSSC | LLHPITSIEY | QWIQGRLKAE | QREELATSFT | 
    450:
    SLLAYGLSLI | RKFRSVFPLS | VSDSPSRLQS | LLRVLVQMCK | MKAFGELCPD | 
    500:
    SAPLPQLVSE | ALRMGTVEWF | HLMQQHHQPM | VQGILEAGKA | LLSLVQDVMG | 
    550:
    DLYQCRRTWN | KIFHNVLKID | LFTMAFLELQ | WLVAKRVQDH | TAAVGDLVSP | 
    600:
    DVGESLFQLY | VSLREFCQLG | PSDSHEVLAL | DGFHRWFQSA | IPSWLQRTYS | 
    650:
    VALERVQRAV | QMDSLVPLGE | LTKHSTSAVD | LSTCFAQISH | TARQLDWPDP | 
    700:
    EEAFMITVKF | VEDTCRLALV | YCSLIKARAR | ELSAVQKDQS | QAADMLCVVV | 
    750:
    NNVERLRLII | DKLPTQLAWE | ALEQRVGAVL | EQGQLQNTLH | TQLQGALAGL | 
    800:
    GHEIRTGVRT | LAEQLEVGIA | THIQKLIDAK | GSILPEDAIL | PLMKFLEVKL | 
    850:
    CYMNTNLVQE | NFSSLLTLLW | THTLTVLVEA | AASHRNSSLA | SSRLKVALQN | 
    900:
    LEICFHAEGC | GLPPEALHTD | TFLALQSDLE | LQAASSRELI | QKYFRSRIQQ | 
    950:
    QAETTSERLG | AVTVKASYRA | SEQKLHVELL | SASSLLPLDS | NGSSDPFVQL | 
    1000:
    TLEPRHEFPE | LAPRETQKHK | KELHPLFDET | FEFLVPAEPC | QKDGACLLLT | 
    1050:
    VLDHDRLGAD | DLEGEAFLPL | CRVPGLTGCV | EPGEAPQMRL | PLTYPAPNGD | 
    1088:
    PILRLLESRK | GDREAQAFVK | LRRQRAKQAS | QHAPATEP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Protein unc-13 homolog D
    Cat.:
    E4438r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Rat Protein unc-13 homolog D
    Cat.:
    E4438h
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Rat Protein unc-13 homolog D
    Cat.:
    E4438m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Protein unc-13 homolog D
    Cat.:
    U4438r
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Protein unc-13 homolog D
    Cat.:
    U4438h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Protein unc-13 homolog D
    Cat.:
    U4438m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Protein unc-13 homolog D
    Cat.:
    P4438Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Protein unc-13 homolog D
    Cat.:
    P4438Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Protein unc-13 homolog D
    Cat.:
    P4438Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Protein unc-13 homolog D
    Monoclonal Antibody for Rat Protein unc-13 homolog D
    Monoclonal Antibody for Rat Protein unc-13 homolog D
    Protein for Rat Protein unc-13 homolog D
    Protein for Rat Protein unc-13 homolog D
    Protein for Rat Protein unc-13 homolog D

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    References
    1. 1.
      "Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13-isoform."
      Koch H. , Hofmann K. , Brose N.
      Biochem. J.349:247-253(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      strain: Sprague-Dawley.
      tissue: Lung.
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