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Index > Protein center > Unc45a(Gene name) > Mouse
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  • Unc45a (Gene name),
  • Protein unc-45 homolog A (Protein name ),  UN45A_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Unc45a(Smap1);
    Protein name:
    Protein unc-45 homolog A(Unc-45A);
    Alternative:
    Stromal membrane-associated protein 1(SMAP-1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with PGR isoforms A and B as well as with NR3C1 in the absence of ligand, and with HSP90AB1. Binding to HSP90AB1 involves 2 UNC45A monomers per HSP90AB1 dimer.
    Function:
    May act as co-chaperone for HSP90 (Potential). Prevents the stimulation of HSP90AB1 ATPase activity by AHSA1. Positive factor in promoting PGR function in the cell (By similarity). May be necessary for proper folding of myosin (Potential). Necessary for normal cell proliferation. Necessary for normal myotube formation and myosin accumulation during muscle cell development. May play a role in erythropoiesis in stroma cells in the spleen.
    Subcellular Location:
    Cytoplasm Cytoplasm perinuclear region Nucleus Predominant in the perinuclear region. Little protein in the nucleus.
    Protein Attributes:
    Sequence length:
    944
    Sequence:
    50:
    MTVSGPETPE | PRPSDPGASS | AEQLRKEGNE | LFKCGDYEGA | LTAYTQALSL | 
    100:
    GATPQDQAIL | HRNRAACHLK | LEDYSKAESE | ASKAIEKDGG | DVKALYRRSQ | 
    150:
    ALEKLGRLDQ | AVLDLKRCVS | LEPKNKVFQE | SLRNIGGQIQ | EKVRYMSSTD | 
    200:
    AKVEQMFQIL | LDPKEKGTEK | KQKASQNLVV | LAREDAGAEK | IFRSNGVQLL | 
    250:
    QRLLDTEETD | LMLAALRTLV | GICSEHQSRT | VATLSVLGTR | RVVSILGVEN | 
    300:
    QAVSLAACHL | LQVIFDALKE | GVKKGFRGKE | GAIIVDPARE | LKVLINSLLE | 
    350:
    LLTEVGVSGQ | GRDNALTLLI | KMVPRKSPKD | PNNSLTLWVI | DQGLKKILEV | 
    400:
    GGSLQDAAGE | LTVTANSRMS | ASILLSKLFD | DLKCDAEREN | FHRLCENYIR | 
    450:
    NWFEGHGLAG | KLRAIQTVSC | LLQGPCDAGN | RALELSGVME | SVIALCASER | 
    500:
    EEEQLVAVEA | LIHAAGKAKR | ASFITANGVS | LLKDLYKGSE | RDSIRIRALV | 
    550:
    GLCKLGSAGG | TDFSMKQFAE | GSTLKLAKQC | RKWLCNDQID | AGTRRWAVEG | 
    600:
    LAYLTFDADV | KEEFVEDEAA | LKALFQLSRS | EERSVLFAVG | SALVNCTNSY | 
    650:
    DYEEPDPKMV | ELAKYAKQHV | PEQHPKDKPS | FVRARVKKLL | AAGVVSAMTC | 
    700:
    MVKTESPVLT | NSCRELLSRV | FLALVEEVED | RGTVVAQGGG | KALLPLALEG | 
    750:
    TDVGQTKAAQ | ALAKLTITSN | PEMTFPGERI | YEVVRPLVSL | LHLSCSGLQN | 
    800:
    FEALMALTNL | AGISERLRQK | ILKEKAVPMI | EGYMFEEHEM | IRRAATECMC | 
    850:
    NLAMSKEVQD | LFEAQGNDRL | KLLVLYSGED | DELLRRAAAG | GLAMLTSMRP | 
    900:
    ALCSRIPQVT | THWLEILQAL | LLSPNQELQH | RGTVVVLNMM | QSSKEIAGTL | 
    944:
    MESEVLEILS | VLAKGEESPV | TRAAAACLEK | AVEYRLIQPN | QDGE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Unc-45A
    Cat.:
    E14842h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Unc-45A
    Cat.:
    E14842m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Unc-45A
    Cat.:
    E14842r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Unc-45A
    Cat.:
    U14842r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Unc-45A
    Cat.:
    U14842h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Unc-45A
    Cat.:
    U14842m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Unc-45A
    Cat.:
    P14842Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Unc-45A
    Cat.:
    P14842Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Unc-45A
    Cat.:
    P14842Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Unc-45A
    Monoclonal Antibody for Mouse Unc-45A
    Monoclonal Antibody for Mouse Unc-45A
    Protein for Mouse Unc-45A
    Protein for Mouse Unc-45A
    Protein for Mouse Unc-45A

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Blastocyst.
      tissue: Cerebellum.
      tissue: Skin.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary tumor.
    3. 3.
      "A new type-II membrane protein in erythropoietic organs enhances erythropoiesis."
      Yanai N. , Sato Y. , Obinata M.
      Leukemia11:484-485(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    4. 4.
      "Two mammalian UNC-45 isoforms are related to distinct cytoskeletal and muscle-specific functions."
      Price M.G. , Landsverk M.L. , Barral J.M. , Epstein H.F.
      J. Cell Sci.115:4013-4023(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
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